Absence of Coronary Artery Calcification in Middle-Aged Familial Hypercholesterolemia Patients Without Atherosclerotic Cardiovascular Disease
Mszar R, Grandhi GR, Valero-Elizondo J, Virani SS, Blankstein R, Blaha M, Mata P, Miname MH, Al Rasadi K, Krumholz HM, Santos RD, Nasir K. Absence of Coronary Artery Calcification in Middle-Aged Familial Hypercholesterolemia Patients Without Atherosclerotic Cardiovascular Disease. JACC Cardiovascular Imaging 2019, 13: 1090-1092. PMID: 31843585, DOI: 10.1016/j.jcmg.2019.11.001.Peer-Reviewed Original ResearchMeSH KeywordsCoronary Artery DiseaseFemaleHeart Disease Risk FactorsHumansHyperlipoproteinemia Type IIMaleMiddle AgedPrevalenceRisk AssessmentVascular CalcificationWhole Genome Sequencing to Characterize Monogenic and Polygenic Contributions in Patients Hospitalized with Early-Onset Myocardial Infarction
Khera AV, Chaffin M, Zekavat S, Collins RL, Roselli C, Natarajan P, Lichtman JH, D'Onofrio G, Mattera J, Dreyer R, Spertus JA, Taylor KD, Psaty BM, Rich SS, Post W, Gupta N, Gabriel S, Lander E, Ida Chen Y, Talkowski ME, Rotter JI, Krumholz HM, Kathiresan S. Whole Genome Sequencing to Characterize Monogenic and Polygenic Contributions in Patients Hospitalized with Early-Onset Myocardial Infarction. Circulation 2019, 139: 1593-1602. PMID: 30586733, PMCID: PMC6433484, DOI: 10.1161/circulationaha.118.035658.Peer-Reviewed Original Research