2023
Racial/ethnic disparities in PM2.5-attributable cardiovascular mortality burden in the United States
Ma Y, Zang E, Opara I, Lu Y, Krumholz H, Chen K. Racial/ethnic disparities in PM2.5-attributable cardiovascular mortality burden in the United States. Nature Human Behaviour 2023, 7: 2074-2083. PMID: 37653149, PMCID: PMC10901568, DOI: 10.1038/s41562-023-01694-7.Peer-Reviewed Original ResearchMeSH KeywordsBlack or African AmericanCardiovascular DiseasesEthnicityHispanic or LatinoHumansParticulate MatterRacial GroupsUnited StatesWhiteConceptsNon-Hispanic White peopleCVD deathMortality burdenNon-Hispanic black peopleCardiovascular disease mortality ratesDisease mortality ratesNon-Hispanic blacksRace/ethnicityMortality rateLong-term exposureWhite peopleEthnic disparitiesHealth benefitsHispanic peopleSignificant differencesBurdenDeathUS countiesEthnic groupsAbsolute disparityAssociationExposureEthnic minoritiesDisparitiesAmbient fine particulate matter (PM2.5) concentrations
2022
Trends in Racial and Ethnic Disparities in Barriers to Timely Medical Care Among Adults in the US, 1999 to 2018
Caraballo C, Ndumele CD, Roy B, Lu Y, Riley C, Herrin J, Krumholz HM. Trends in Racial and Ethnic Disparities in Barriers to Timely Medical Care Among Adults in the US, 1999 to 2018. JAMA Health Forum 2022, 3: e223856. PMID: 36306118, PMCID: PMC9617175, DOI: 10.1001/jamahealthforum.2022.3856.Peer-Reviewed Original ResearchMeSH KeywordsAdultBlack PeopleCohort StudiesCross-Sectional StudiesEthnicityFemaleHispanic or LatinoHumansMaleMiddle AgedConceptsTimely medical careSerial cross-sectional studyNational Health Interview SurveyCross-sectional studyHealth Interview SurveyMedical careLack of transportationEthnic disparitiesHispanics/LatinosWhite individualsEthnicity groupsInterview SurveyCost of careSelf-reported raceStudy cohortClinic hoursMAIN OUTCOMEMedical officesCarePrevalenceLatino individualsBlack individualsSignificant differencesSignificant increasePopulation groupsEvaluation of Temporal Trends in Racial and Ethnic Disparities in Sleep Duration Among US Adults, 2004-2018
Caraballo C, Mahajan S, Valero-Elizondo J, Massey D, Lu Y, Roy B, Riley C, Annapureddy AR, Murugiah K, Elumn J, Nasir K, Nunez-Smith M, Forman HP, Jackson CL, Herrin J, Krumholz HM. Evaluation of Temporal Trends in Racial and Ethnic Disparities in Sleep Duration Among US Adults, 2004-2018. JAMA Network Open 2022, 5: e226385. PMID: 35389500, PMCID: PMC8990329, DOI: 10.1001/jamanetworkopen.2022.6385.Peer-Reviewed Original ResearchMeSH KeywordsAdultBlack PeopleCross-Sectional StudiesEthnicityFemaleHispanic or LatinoHumansMaleMiddle AgedSleepConceptsCross-sectional studyLong sleep durationSleep durationWhite individualsBlack individualsLatino individualsEthnic differencesSerial cross-sectional studyNational Health Interview Survey dataHealth Interview Survey dataSelf-reported sleep durationShort sleep durationInterview Survey dataMiddle-aged adultsSelf-reported raceEstimated prevalenceMAIN OUTCOMELong sleepSleep deficiencyHigher household incomeEthnic disparitiesAge groupsHealth disparitiesPrevalenceSleep disparities
2020
Transethnic Transferability of a Genome-Wide Polygenic Score for Coronary Artery Disease
Fahed AC, Aragam KG, Hindy G, Chen YI, Chaudhary K, Dobbyn A, Krumholz HM, Sheu WHH, Rich SS, Rotter JI, Chowdhury R, Cho J, Do R, Ellinor PT, Kathiresan S, Khera AV. Transethnic Transferability of a Genome-Wide Polygenic Score for Coronary Artery Disease. Circulation Genomic And Precision Medicine 2020, 14: e003092. PMID: 33284643, PMCID: PMC7887053, DOI: 10.1161/circgen.120.003092.Peer-Reviewed Original ResearchEvaluation of STEMI Regionalization on Access, Treatment, and Outcomes Among Adults Living in Nonminority and Minority Communities
Hsia RY, Krumholz H, Shen YC. Evaluation of STEMI Regionalization on Access, Treatment, and Outcomes Among Adults Living in Nonminority and Minority Communities. JAMA Network Open 2020, 3: e2025874. PMID: 33196809, PMCID: PMC7670311, DOI: 10.1001/jamanetworkopen.2020.25874.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedAged, 80 and overBlack or African AmericanCaliforniaCause of DeathCohort StudiesFemaleHealth Services AccessibilityHealthcare DisparitiesHispanic or LatinoHospitalizationHumansMaleMiddle AgedMinority GroupsMortalityNon-Randomized Controlled Trials as TopicPercutaneous Coronary InterventionRegional Medical ProgramsResidence CharacteristicsST Elevation Myocardial InfarctionTime-to-TreatmentWhite PeopleConceptsST-segment elevation myocardial infarctionElevation myocardial infarctionPercutaneous coronary interventionPCI-capable hospitalsZip codesNon-Hispanic whitesPatient's countyCause mortalityCohort studyCoronary interventionPCI hospitalsPCI treatmentWhite patientsCapable hospitalsMyocardial infarctionTop tertileInpatient dataMAIN OUTCOMEPatientsSTEMI regionalizationSmall improvementHospitalPotential mechanismsSame dayHispanic populationAssociation Between Sociodemographic Determinants and Disparities in Stroke Symptom Awareness Among US Young Adults
Mszar R, Mahajan S, Valero-Elizondo J, Yahya T, Sharma R, Grandhi GR, Khera R, Virani SS, Lichtman J, Khan SU, Cainzos-Achirica M, Vahidy FS, Krumholz HM, Nasir K. Association Between Sociodemographic Determinants and Disparities in Stroke Symptom Awareness Among US Young Adults. Stroke 2020, 51: 3552-3561. PMID: 33100188, DOI: 10.1161/strokeaha.120.031137.Peer-Reviewed Original ResearchConceptsNational Health Interview SurveyCommon stroke symptomsStroke symptomsHealth Interview SurveyYoung adultsUS young adultsSymptom awarenessFocused public health interventionsInterview SurveyStroke symptom awarenessHigh-risk characteristicsPublic health interventionsArms/legsCertain sociodemographic subgroupsLow education levelStroke incidenceSevere headacheSingle symptomStudy populationTimely diagnosisHigher oddsStroke rateHispanic ethnicityGeneral populationSociodemographic determinants
2010
Patterns of moderate and vigorous physical activity in obese and overweight compared with non‐overweight children
DORSEY KB, HERRIN J, KRUMHOLZ HM. Patterns of moderate and vigorous physical activity in obese and overweight compared with non‐overweight children. Pediatric Obesity 2010, 6: e547-e555. PMID: 20883127, PMCID: PMC3815589, DOI: 10.3109/17477166.2010.490586.Peer-Reviewed Original ResearchConceptsVigorous physical activityOW/OBNon-overweight childrenMVPA boutsPhysical activityGreater body mass index z-scoreVPA boutsOW/OB groupBody mass index z-scoreMean daily MVPANon-overweight groupLess physical activityIndex z-scoreMinutes of MVPANon-overweight peersObese childrenObese participantsOverweight childrenOB groupDaily MVPASustained MVPADistinct patternsOB participantsMVPAConsecutive bouts
2008
Factors Associated With Longer Time From Symptom Onset to Hospital Presentation for Patients With ST-Elevation Myocardial Infarction
Ting HH, Bradley EH, Wang Y, Lichtman JH, Nallamothu BK, Sullivan MD, Gersh BJ, Roger VL, Curtis JP, Krumholz HM. Factors Associated With Longer Time From Symptom Onset to Hospital Presentation for Patients With ST-Elevation Myocardial Infarction. JAMA Internal Medicine 2008, 168: 959-968. PMID: 18474760, PMCID: PMC4858313, DOI: 10.1001/archinte.168.9.959.Peer-Reviewed Original ResearchConceptsST-elevation myocardial infarctionMyocardial infarctionHospital presentationSymptom onsetPatient subgroupsRisk factorsOnset of symptomsQuality of careRace/ethnicityNational registryPatient responsivenessInfarctionPatientsReference groupSubgroupsWomenMenCareOnsetMinutesPresentationYearsHoursGeometric meanDiabetics
2005
Enrolling Older Persons in Cancer Trials: The Effect of Sociodemographic, Protocol, and Recruitment Center Characteristics
Gross CP, Herrin J, Wong N, Krumholz HM. Enrolling Older Persons in Cancer Trials: The Effect of Sociodemographic, Protocol, and Recruitment Center Characteristics. Journal Of Clinical Oncology 2005, 23: 4755-4763. PMID: 16034051, DOI: 10.1200/jco.2005.14.365.Peer-Reviewed Original ResearchConceptsCancer trialsOlder personsRecruitment centerElderly enrollmentProportion of patientsEffect of patientProstate cancer trialsPatient-level variationFinal study sampleNational Cancer InstituteCross-sectional analysisEffects of sociodemographicsNonwhite patientsTrial participantsOutlier centersCancer InstitutePatientsEnrollment centerMultivariate analysisLikelihood of participantsCancer typesLogistic multilevel modelsTrialsCenter characteristicsStudy sampleThe impact of socioeconomic status and race on trial participation for older women with breast cancer
Gross CP, Filardo G, Mayne ST, Krumholz HM. The impact of socioeconomic status and race on trial participation for older women with breast cancer. Cancer 2005, 103: 483-491. PMID: 15597407, DOI: 10.1002/cncr.20792.Peer-Reviewed Original ResearchMeSH KeywordsAgedAsianBlack or African AmericanBreast NeoplasmsCase-Control StudiesClinical Trials as TopicFemaleHispanic or LatinoHumansLogistic ModelsMedicaidMultivariate AnalysisNational Institutes of Health (U.S.)Odds RatioPatient SelectionPovertySEER ProgramUnemploymentUnited StatesWhite PeopleConceptsBreast cancer trialsTrial participationOlder womenBreast cancerSocioeconomic statusMedicaid insuranceTrial enrollmentCancer patientsCancer trialsMultivariable logistic regression modelBreast cancer patientsMedicaid insurance coverageAssociation of SESHigh-poverty zip codesCase-control studyPopulation-based sampleLow socioeconomic statusLogistic regression modelsImpact of SESWhite patientsBlack patientsSEER areasBlack raceElderly womenTrial participants
2004
Racial and Ethnic Differences in Time to Acute Reperfusion Therapy for Patients Hospitalized With Myocardial Infarction
Bradley EH, Herrin J, Wang Y, McNamara RL, Webster TR, Magid DJ, Blaney M, Peterson ED, Canto JG, Pollack CV, Krumholz HM. Racial and Ethnic Differences in Time to Acute Reperfusion Therapy for Patients Hospitalized With Myocardial Infarction. JAMA 2004, 292: 1563-1572. PMID: 15467058, DOI: 10.1001/jama.292.13.1563.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overAngioplasty, Balloon, CoronaryAsian PeopleBlack PeopleFemaleHispanic or LatinoHospitalsHumansInsurance, HospitalizationMaleMiddle AgedMyocardial InfarctionOutcome Assessment, Health CarePatient AdmissionRetrospective StudiesSocioeconomic FactorsThrombolytic TherapyTime and Motion StudiesTime FactorsUnited StatesWhite PeopleConceptsST-segment elevation myocardial infarctionAcute reperfusion therapyElevation myocardial infarctionMyocardial infarctionReperfusion therapyAfrican American/BlackBalloon timeInsurance statusAmerican/BlackEthnic differencesPercutaneous coronary interventionBundle branch blockAsian/Pacific IslandersHealth care disparitiesRace/ethnicity differencesRace/ethnicityClinical characteristicsCoronary interventionFibrinolytic therapyHospital arrivalNonwhite patientsPrimary reperfusionWhite patientsUS cohortHospital characteristics