2019
The relationship between off-hours admissions for primary percutaneous coronary intervention, door-to-balloon time and mortality for patients with ST-elevation myocardial infarction in England: a registry-based prospective national cohort study
Jayawardana S, Salas-Vega S, Cornehl F, Krumholz HM, Mossialos E. The relationship between off-hours admissions for primary percutaneous coronary intervention, door-to-balloon time and mortality for patients with ST-elevation myocardial infarction in England: a registry-based prospective national cohort study. BMJ Quality & Safety 2019, 29: 541-549. PMID: 31831635, PMCID: PMC7362773, DOI: 10.1136/bmjqs-2019-010067.Peer-Reviewed Original ResearchConceptsPrimary percutaneous coronary interventionOff-hours admissionPercutaneous coronary interventionDTB timeCoronary interventionBalloon timeST-elevation myocardial infarction (STEMI) patientsElevation myocardial infarction patientsProspective national cohort studyST-elevation myocardial infarctionCent of admissionsMedian DTB timeOff-hour effectPatient risk factorsProspective observational studyRecords of patientsPrimary outcome measureNational cohort studyTimeliness of careMyocardial infarction patientsHierarchical logistic regression modelsLogistic regression modelsHospital mortalityCohort studySecondary outcomesSex-Based Differences in Presentation, Treatment, and Complications Among Older Adults Hospitalized for Acute Myocardial Infarction
Nanna MG, Hajduk AM, Krumholz HM, Murphy TE, Dreyer RP, Alexander KP, Geda M, Tsang S, Welty FK, Safdar B, Lakshminarayan DK, Chaudhry SI, Dodson JA. Sex-Based Differences in Presentation, Treatment, and Complications Among Older Adults Hospitalized for Acute Myocardial Infarction. Circulation Cardiovascular Quality And Outcomes 2019, 12: e005691. PMID: 31607145, PMCID: PMC6913190, DOI: 10.1161/circoutcomes.119.005691.Peer-Reviewed Original ResearchMeSH KeywordsAge FactorsAgedAged, 80 and overComorbidityDisability EvaluationFemaleHealth Status DisparitiesHealthcare DisparitiesHumansLife StyleMaleMyocardial RevascularizationNon-ST Elevated Myocardial InfarctionPatient AdmissionPrevalenceProspective StudiesRisk AssessmentRisk FactorsSex FactorsSocial Determinants of HealthST Elevation Myocardial InfarctionTime FactorsTreatment OutcomeUnited StatesConceptsAcute myocardial infarctionSex-based differencesPercutaneous coronary interventionFunctional impairmentOlder adultsHospital complicationsCoronary interventionOlder patientsCoronary diseaseMyocardial infarctionAge-related functional impairmentsAge-associated functional impairmentsLower ratesPrior coronary diseaseObstructive coronary diseaseProspective observational studyNSTEMI subgroupSTEMI subgroupUnderwent revascularizationAcute myocardialChest painClinical presentationAMI subgroupRisk factorsHigh prevalence
1994
Clinical utility of transthoracic two-dimensional and Doppler echocardiography
Krumholz H, Douglas P, Goldman L, Waksmonski C. Clinical utility of transthoracic two-dimensional and Doppler echocardiography. Journal Of The American College Of Cardiology 1994, 24: 125-131. PMID: 8006255, DOI: 10.1016/0735-1097(94)90552-5.Peer-Reviewed Original ResearchConceptsNew diagnosisChart reviewEchocardiographic examinationMitral regurgitationClinical utilityLeft ventricular wall motion abnormalitiesTertiary care teaching hospitalVentricular wall motion abnormalitiesGreater mitral regurgitationProspective observational studyUse of echocardiographyWall motion abnormalitiesPharmacologic treatmentTransthoracic twoDoppler echocardiographyMotion abnormalitiesPhysician interviewsTeaching hospitalObservational studyEchocardiographyClinical practiceOutpatientsInpatientsPatient diagnosisContemporary echocardiography