2023
Mortality, incarceration and cost implications of fentanyl felonization laws: A modeling study
Savinkina A, Jurecka C, Gonsalves G, Barocas J. Mortality, incarceration and cost implications of fentanyl felonization laws: A modeling study. International Journal Of Drug Policy 2023, 121: 104175. PMID: 37729682, PMCID: PMC10840895, DOI: 10.1016/j.drugpo.2023.104175.Peer-Reviewed Original ResearchMeSH KeywordsAnalgesics, OpioidDrug OverdoseFentanylHumansOpiate OverdoseOpioid-Related DisordersUnited StatesEarly OxyContin Marketing Linked To Long-Term Spread Of Infectious Diseases Associated With Injection Drug Use
Dennett J, Gonsalves G. Early OxyContin Marketing Linked To Long-Term Spread Of Infectious Diseases Associated With Injection Drug Use. Health Affairs 2023, 42: 1081-1090. PMID: 37467441, PMCID: PMC10521060, DOI: 10.1377/hlthaff.2023.00146.Peer-Reviewed Original ResearchMeSH KeywordsAnalgesics, OpioidCommunicable DiseasesDrug OverdoseHumansMarketingOpioid-Related DisordersOxycodoneUnited StatesConceptsInjection drug useDrug useAdverse long-term outcomesInfectious diseasesReformulation of OxyContinAcute hepatitis ALong-term outcomesOpioid-related overdosesInitial marketingFatal drug overdosesBacterial complicationsHepatitis ADrug overdosesEffects of exposureOpioid epidemicViral infectionGreater burdenIllicit drugsLow exposureComplicationsHigh exposureOverdosesOutcomesDiseaseOxyContinPopulation-Level Health Effects of Involuntary Displacement of People Experiencing Unsheltered Homelessness Who Inject Drugs in US Cities
Barocas J, Nall S, Axelrath S, Pladsen C, Boyer A, Kral A, Meehan A, Savinkina A, Peery D, Bien M, Agnew-Brune C, Goldshear J, Chiang J, Linas B, Gonsalves G, Bluthenthal R, Mosites E, Wortley P, Todd J, Melton D, Flynn C, German D, Klevens M, Doherty R, O'Cleirigh C, Jimenez A, Clyde T, Poe J, Vaaler M, Deng J, Al-Tayyib A, Shodell D, Higgins E, Griffin V, Sanger C, Khuwaja S, Lopez Z, Padgett P, Kwa Sey E, Ma Y, Santacruz H, Brantley M, Mathews C, Marr J, Spencer E, Nixon W, Forrest D, Anderson B, Tate A, Abrego M, Robinson W, Barak N, Beckford J, Braunstein S, Rivera A, Carrillo S, Ibrahim A, Wogayehu A, Moraga L, Brady K, Shinefeld J, Nnumolu C, Menza T, Orellana E, Bhattari A, Flynn A, Chambers O, Ramos M, McFarland W, Lin J, Miller D, Miranda De Leon S, Rolon-Colon Y, Martinez M, Jaenicke T, Glick S, Kienzle J, Smith B, Reid T, Opoku J, Kuo I, Adams M, Baugher A, Broz D, Burnett J, Chambers S, Chapin-Bardales J, Denning P, Finlayson T, Handanagic S, Hickey T, Kanny D, Lee K, Lewis R, Morris E, Olansky E, Robbins T, Sionean C, Smith A, Teplinskaya A, Trujillo K, Wejnert C, Whiteman A, Xia M. Population-Level Health Effects of Involuntary Displacement of People Experiencing Unsheltered Homelessness Who Inject Drugs in US Cities. JAMA 2023, 329: 1478-1486. PMID: 37036716, PMCID: PMC10087093, DOI: 10.1001/jama.2023.4800.Peer-Reviewed Original ResearchConceptsNational HIV Behavioral Surveillance SystemInitiation of medicationInjection-related infectionsOpioid use disorderUse disordersHealth effectsInjection drug useLong-term health effectsDrug-related morbidityPopulation attributable fractionBehavioral Surveillance SystemSubstance use disordersMAIN OUTCOMEOverdose deathsRepresentative cohortAdditional deathsOverdose mortalityHealth outcomesDrug useNatural historyDisease controlMortalityDisorder outcomesDrugsHealth implicationsGeographic and temporal trends in fentanyl-detected deaths in Connecticut, 2009–2019
Lu H, Crawford F, Gonsalves G, Grau L. Geographic and temporal trends in fentanyl-detected deaths in Connecticut, 2009–2019. Annals Of Epidemiology 2023, 79: 32-38. PMID: 36669599, PMCID: PMC10163838, DOI: 10.1016/j.annepidem.2023.01.009.Peer-Reviewed Original Research
2022
Commentary Article: Opioid use Disorder Cascade of Care Framework Design: A Roadmap
Williams AR, Johnson KA, Thomas CP, Reif S, Socías ME, Henry BF, Neighbors C, Gordon AJ, Horgan C, Nosyk B, Drexler K, Krawczyk N, Gonsalves GS, Hadland SE, Stein BD, Fishman M, Kelley AT, Pincus HA, Olfson M. Commentary Article: Opioid use Disorder Cascade of Care Framework Design: A Roadmap. Substance Abuse 2022, 43: 1207-1214. PMID: 35657670, PMCID: PMC9577537, DOI: 10.1080/08897077.2022.2074604.Peer-Reviewed Original ResearchMeSH KeywordsAnalgesics, OpioidBuprenorphineDrug OverdoseHumansOpiate Substitution TreatmentOpioid-Related DisordersPublic HealthConceptsOpioid use disorderHealth systemGold standard treatmentUnintentional overdose deathsYears of ageSpread of HIVQuality improvement effortsTreatment initiationClinical outcomesStandard treatmentOverdose deathsUse disordersUS deathsCare frameworkEarly dropoutDeathTreatmentImprovement effortsMedicationsOpioidsHIVYearsAvailable dataIndividuals
2019
Suspected heroin-related overdoses incidents in Cincinnati, Ohio: A spatiotemporal analysis
Li ZR, Xie E, Crawford FW, Warren JL, McConnell K, Copple JT, Johnson T, Gonsalves GS. Suspected heroin-related overdoses incidents in Cincinnati, Ohio: A spatiotemporal analysis. PLOS Medicine 2019, 16: e1002956. PMID: 31714940, PMCID: PMC6850525, DOI: 10.1371/journal.pmed.1002956.Peer-Reviewed Original ResearchConceptsRisk of overdoseRisk of incidentBlock groupHarm reduction measuresPoisson regression modelsHighest overdose ratesOpioid misuseRisk factorsOpioid epidemicOpiate overdosesOverdose incidentsOpioid overdosesOverdose ratesNature of incidentsEmergency callsMale populationMedian household incomeTreatment programOverdose emergencyHealth policySpatiotemporal risk factorsLack of informationDemographic characteristicsHigher numberOverdoses