2023
Cortical GABA Levels Are Reduced in Post-Acute COVID-19 Syndrome
Marinkovic K, White D, Myers A, Parker K, Arienzo D, Mason G. Cortical GABA Levels Are Reduced in Post-Acute COVID-19 Syndrome. Brain Sciences 2023, 13: 1666. PMID: 38137114, PMCID: PMC10741691, DOI: 10.3390/brainsci13121666.Peer-Reviewed Original ResearchAcute COVID-19 illnessCOVID-19 illnessGABA levelsN-acetylaspartatePost-acute COVID-19 syndromeCortical GABA levelsPersistent cognitive dysfunctionPost-acute sequelaeCOVID-19 syndromeExcitation/inhibition imbalancePoor sleep qualityProton magnetic resonance spectroscopyDepression/anxietyQuality of lifePersistent neuroinflammationBrain fogCortical hyperexcitabilityLong COVIDAlcohol intakeCognitive dysfunctionNeuronal integrityNeurocognitive dysfunctionNeurochemical aspectsSleep qualityOccipital cortex
2010
Regional metabolite levels and turnover in the awake rat brain under the influence of nicotine
Wang J, Jiang L, Jiang Y, Ma X, Chowdhury GM, Mason GF. Regional metabolite levels and turnover in the awake rat brain under the influence of nicotine. Journal Of Neurochemistry 2010, 113: 1447-1458. PMID: 20345764, PMCID: PMC2903655, DOI: 10.1111/j.1471-4159.2010.06684.x.Peer-Reviewed Original ResearchConceptsRat brainN-acetylaspartateAcute nicotine treatmentBrain glucose oxidationAmino acid neurotransmittersInfluence of nicotineConcentration of glutamateRegional metabolite levelsAwake rat brainRelated neurochemicalsNicotine treatmentInhibitory neurotransmissionAcute effectsOlfactory bulbOccipital cortexNeurotransmitter cyclingGABA synthesisNicotineStriatumBrainMetabolite levelsWidespread drugGABACortexPotential interplay