2020
759. Where can we find active TB? Case finding at community sites and alcohol based venues (ABVs) in rural South Africa
Choi K, Shenoi S, Moll A, Friedland G. 759. Where can we find active TB? Case finding at community sites and alcohol based venues (ABVs) in rural South Africa. Open Forum Infectious Diseases 2020, 7: s426-s426. PMCID: PMC7778049, DOI: 10.1093/ofid/ofaa439.949.Peer-Reviewed Original ResearchAlcohol Use Disorders Identification TestHazardous alcohol useActive TBTB casesAlcohol useCase detectionOlder ageMean AUDITActive TB diseaseUseful adjunctive strategyPrimary care clinicsHIV rapid testsCommunity health workersTuberculosis case detectionResource limited settingsCases of TBDisorders Identification TestSubstance abuse servicesTB diseaseRandom glucoseBlood pressureMedian ageCare clinicsAdjunctive strategiesRisk factors
2012
Risk factors for mortality among MDR- and XDR-TB patients in a high HIV prevalence setting
Gandhi N, Andrews J, Brust J, Montreuil R, Weissman D, Heo M, Moll A, Friedland G, Shah N. Risk factors for mortality among MDR- and XDR-TB patients in a high HIV prevalence setting. The International Journal Of Tuberculosis And Lung Disease 2012, 16: 90-97. PMID: 22236852, PMCID: PMC3302205, DOI: 10.5588/ijtld.11.0153.Peer-Reviewed Original ResearchMeSH KeywordsAdultAIDS-Related Opportunistic InfectionsAnti-Retroviral AgentsAntitubercular AgentsCD4 Lymphocyte CountCoinfectionDrug Resistance, Multiple, BacterialExtensively Drug-Resistant TuberculosisFemaleHIV InfectionsHumansMaleMarkov ChainsMonte Carlo MethodPrevalencePrognosisProportional Hazards ModelsRetrospective StudiesRisk AssessmentRisk FactorsSouth AfricaSurvival AnalysisTime FactorsTuberculosis, Multidrug-ResistantTuberculosis, PulmonaryConceptsHuman immunodeficiency virusXDR-TB patientsRisk factorsAntiretroviral therapyXDR-TBDrug-resistant (XDR) TBImmunosuppressed human immunodeficiency virusStrong independent risk factorHigh HIV prevalence settingsMDR-TB patientsTB treatment programsIndependent risk factorYear of diagnosisDrug-resistant tuberculosisHIV prevalence settingsCells/Principal risk factorsCase-control studyAmplification of resistanceHigh mortality rateART initiationHIV testingImmunodeficiency virusPrevalence settingsMortality rate
2010
Predictors of Multidrug- and Extensively Drug-Resistant Tuberculosis in a High HIV Prevalence Community
Andrews JR, Shah NS, Weissman D, Moll AP, Friedland G, Gandhi NR. Predictors of Multidrug- and Extensively Drug-Resistant Tuberculosis in a High HIV Prevalence Community. PLOS ONE 2010, 5: e15735. PMID: 21209951, PMCID: PMC3012092, DOI: 10.1371/journal.pone.0015735.Peer-Reviewed Original ResearchConceptsDrug-resistant tuberculosisTB treatment failureXDR-TBHIV prevalence settingsRisk factorsTreatment failureOdds ratioMDR/XDR-TBOnly significant risk factorRetrospective case-control studyDrug resistanceMDR-TB patientsSignificant risk factorsStrong risk factorMultivariate logistic regressionTB drug resistanceCase-control studyHigh HIV prevalence communitiesDemographic risk factorsDrug susceptibility testing methodsHIV prevalence communitiesTB settingsClinical deteriorationMDR-TBTB treatmentBlood cultures for the diagnosis of multidrug-resistant and extensively drug-resistant tuberculosis among HIV-infected patients from rural South Africa: a cross-sectional study
Heysell SK, Thomas TA, Gandhi NR, Moll AP, Eksteen FJ, Coovadia Y, Roux L, Babaria P, Lalloo U, Friedland G, Shah S. Blood cultures for the diagnosis of multidrug-resistant and extensively drug-resistant tuberculosis among HIV-infected patients from rural South Africa: a cross-sectional study. BMC Infectious Diseases 2010, 10: 344. PMID: 21134279, PMCID: PMC3016377, DOI: 10.1186/1471-2334-10-344.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAIDS-Related Opportunistic InfectionsChildChild, PreschoolCross-Sectional StudiesExtensively Drug-Resistant TuberculosisFemaleHIV InfectionsHumansInfantInfant, NewbornMaleMiddle AgedMycobacterium tuberculosisRetrospective StudiesRisk FactorsRural PopulationSouth AfricaSputumYoung AdultConceptsDrug-resistant TBMycobacterial blood culturesDrug-resistant tuberculosisBlood culturesXDR-TBRural South AfricaMDR-TBM. tuberculosisMycobacterium tuberculosis bacteremiaCross-sectional studyPositive blood culturesDiagnosis of MDRCross-sectional analysisAntiretroviral therapySecondary outcomesSputum cultureTB suspectsRisk factorsPatientsHIVTuberculosisDiagnosisTBSimilar settingsBacteremia
2009
Multidrug-resistant and extensively drug-resistant tuberculosis: consequences for the global HIV community
Shenoi S, Heysell S, Moll A, Friedland G. Multidrug-resistant and extensively drug-resistant tuberculosis: consequences for the global HIV community. Current Opinion In Infectious Diseases 2009, 22: 11-17. PMID: 19532076, PMCID: PMC3013226, DOI: 10.1097/qco.0b013e3283210020.Peer-Reviewed Original ResearchConceptsDrug-resistant tuberculosisHIV patientsHIV communityIntegration of tuberculosisIndependent risk factorCourse of treatmentCommunity-based treatmentHIV careNew rapid diagnosticsRisk factorsClinical careNegative individualsTuberculosisPatientsMultidrugRapid diagnosticsCareTreatmentSusceptibility informationMorbidityHIVInfectionMortalityPhysicians
1996
Invasive Pneumococcal Disease: Clinical Features, Serotypes, and Antimicrobial Resistance Patterns in Cases Involving Patients with and Without Human Immunodeficiency Virus Infection
Frankel R, Virata M, Hardalo C, Altice F, Friedland G. Invasive Pneumococcal Disease: Clinical Features, Serotypes, and Antimicrobial Resistance Patterns in Cases Involving Patients with and Without Human Immunodeficiency Virus Infection. Clinical Infectious Diseases 1996, 23: 577-584. PMID: 8879783, DOI: 10.1093/clinids/23.3.577.Peer-Reviewed Original ResearchConceptsInvasive pneumococcal diseasePneumococcal diseaseClinical featuresPenicillin-resistant pneumococcal infectionsHuman immunodeficiency virus (HIV) diseaseHuman immunodeficiency virus (HIV) infectionCommon capsular typesSource of bacteremiaImmunodeficiency virus infectionOverall mortality rateAntibiotic susceptibility patternPolyvalent pneumococcal vaccineType 9VCommon risk factorsPenicillin-resistant isolatesAntimicrobial resistance patternsPneumococcal infectionPneumococcal vaccineHIV infectionHIV serostatusHIV statusRecurrence rateInvasive diseaseRisk factorsSusceptibility patterns
1991
Human T Lymphotropic Virus Type II (HTLV-II) Infection in a Cohort of New York Intravenous Drug Users: An Old Infection?
Khabbaz R, Hartel D, Lairmore M, Horsburgh C, Schoenbaum E, Roberts B, Hartley T, Friedland G. Human T Lymphotropic Virus Type II (HTLV-II) Infection in a Cohort of New York Intravenous Drug Users: An Old Infection? The Journal Of Infectious Diseases 1991, 163: 252-256. PMID: 1988509, DOI: 10.1093/infdis/163.2.252.Peer-Reviewed Original ResearchConceptsIntravenous drug usersHuman T-lymphotropic virus type II (HTLV-II) infectionHTLV-II infectionType II infectionPolymerase chain reactionRisk factorsHTLV-IIDrug usersHuman immunodeficiency virus (HIV) infectionHIV infection statusImmunodeficiency virus infectionIntravenous drug useMethadone maintenance programTransfusion historyNeedle sharingVirus infectionSerologic resultsSex partnersDrug useShooting galleriesEndemic infectionInfectionOlder ageInfection statusOld infection
1989
Risk Factors for Human Immunodeficiency Virus Infection in Intravenous Drug Users
Schoenbaum E, Hartel D, Selwyn P, Klein R, Davenny K, Rogers M, Feiner C, Friedland G. Risk Factors for Human Immunodeficiency Virus Infection in Intravenous Drug Users. New England Journal Of Medicine 1989, 321: 874-879. PMID: 2770823, DOI: 10.1056/nejm198909283211306.Peer-Reviewed Original ResearchConceptsHuman immunodeficiency virus (HIV) infectionImmunodeficiency virus infectionIntravenous drug usersPercentage of injectionsRisk factorsHIV antibodiesDrug usersIntravenous drugsVirus infectionSex partnersSeroprevalence of HIVIndependent risk factorOnly risk factorMethadone treatment programsNumber of injectionsNon-Hispanic whitesHeterosexual sex partnersHIV infectionLast injectionUsed needlesHigh seroprevalenceDrug useShooting galleriesHIVInfection
1988
Low Occupational Risk of Human Immunodeficiency Virus Infection among Dental Professionals
Klein R, Phelan J, Freeman K, Schable C, Friedland G, Trieger N, Steigbigel N. Low Occupational Risk of Human Immunodeficiency Virus Infection among Dental Professionals. New England Journal Of Medicine 1988, 318: 86-90. PMID: 3422106, DOI: 10.1056/nejm198801143180205.Peer-Reviewed Original ResearchMeSH KeywordsAccidents, OccupationalAcquired Immunodeficiency SyndromeAntibodies, ViralDental AssistantsDental HygienistsDentistryFemaleHepatitis B Surface AntigensHIV AntibodiesHumansMaleNew York CityOccupational DiseasesProfessional PracticePuncturesRisk FactorsSkinSurveys and QuestionnairesUnited StatesConceptsHuman immunodeficiency virusHepatitis B surface antigenBehavioral risk factorsInfection control practicesB surface antigenLow occupational riskDental professionalsOccupational riskHIV infectionRisk factorsOccupational exposureSurface antigenHuman immunodeficiency virus (HIV) infectionFrequent occupational exposureImmunodeficiency virus infectionInfection control precautionsCases of AIDSPotential occupational exposureUnvaccinated subjectsImmunodeficiency syndromeImmunodeficiency virusSerum antibodiesVirus infectionDental practiceSharp instruments