2020
A qualitative study of diphenhydramine injection in Kyrgyz prisons and implications for harm reduction
Meyer JP, Culbert GJ, Azbel L, Bachireddy C, Kurmanalieva A, Rhodes T, Altice FL. A qualitative study of diphenhydramine injection in Kyrgyz prisons and implications for harm reduction. Harm Reduction Journal 2020, 17: 86. PMID: 33129341, PMCID: PMC7603760, DOI: 10.1186/s12954-020-00435-7.Peer-Reviewed Original ResearchConceptsNeedle/syringe programsMethadone maintenance therapyHIV prevention effortsMental health consequencesDiphenhydramine injectionMaintenance therapyOpioid dependenceHIV transmissionState of euphoriaSyringe programsIllicit injectionSkin infectionsMethadone utilizationStudy participantsHarmful drugsHealth consequencesMethadonePrevention effortsHarm reductionAntihistaminesInjectionFurther investigationKyrgyz prisonsVisible woundsQualitative study
2017
Why People Who Inject Drugs Voluntarily Transition Off Methadone in Ukraine
Rozanova J, Marcus R, Taxman FS, Bojko MJ, Madden L, Farnum SO, Mazhnaya A, Dvoriak S, Altice FL. Why People Who Inject Drugs Voluntarily Transition Off Methadone in Ukraine. Qualitative Health Research 2017, 27: 2057-2070. PMID: 28942704, DOI: 10.1177/1049732317732307.Peer-Reviewed Original ResearchDesign and implementation of a factorial randomized controlled trial of methadone maintenance therapy and an evidence-based behavioral intervention for incarcerated people living with HIV and opioid dependence in Malaysia
Bazazi AR, Wickersham JA, Wegman MP, Culbert GJ, Pillai V, Shrestha R, Al-Darraji H, Copenhaver MM, Kamarulzaman A, Altice FL. Design and implementation of a factorial randomized controlled trial of methadone maintenance therapy and an evidence-based behavioral intervention for incarcerated people living with HIV and opioid dependence in Malaysia. Contemporary Clinical Trials 2017, 59: 1-12. PMID: 28479216, PMCID: PMC5557499, DOI: 10.1016/j.cct.2017.05.006.Peer-Reviewed Original ResearchConceptsMethadone maintenance therapyHIV transmission risk behaviorsMaintenance therapyTransmission risk behaviorsEvidence-based behavioral interventionsOpioid dependencePoor HIV treatment outcomesRisk behaviorsBehavioral interventionsHIV treatment outcomesProspective clinical trialsEvidence-based treatmentsHealth-related outcomesOpioid useTreatment receiptClinical trialsTreatment outcomesIncarcerated peopleTherapyStudy participantsFactorial trialHIVTrialsInterventionOutcomesAssessment of an Innovative Voluntary Substance Abuse Treatment Program Designed to Replace Compulsory Drug Detention Centers in Malaysia
Khan F, Krishnan A, Ghani MA, Wickersham JA, Fu JJ, Lim SH, Dhaliwal SK, Kamarulzaman A, Altice FL. Assessment of an Innovative Voluntary Substance Abuse Treatment Program Designed to Replace Compulsory Drug Detention Centers in Malaysia. Substance Use & Misuse 2017, 53: 249-259. PMID: 28635521, PMCID: PMC5664175, DOI: 10.1080/10826084.2016.1267217.Peer-Reviewed Original ResearchConceptsCompulsory drug detention centersDrug useTreatment servicesVoluntary drug treatment centresTreatment programMethadone maintenance therapyEarly treatment outcomesCross-sectional convenience surveyDrug treatment centersSubstance abuse treatment programsDrug treatment programsAddiction treatment servicesSevere mental health issuesPast drug useMental health issuesNational Anti-Drug AgencyMaintenance therapyCare centerClient satisfactionTreatment outcomesTreatment centersDrug use levelsHealth servicesInvoluntary detentionSelf-reported satisfaction
2016
Factors associated with interest in receiving prison-based methadone maintenance therapy in Malaysia
Mukherjee TI, Wickersham JA, Desai MM, Pillai V, Kamarulzaman A, Altice FL. Factors associated with interest in receiving prison-based methadone maintenance therapy in Malaysia. Drug And Alcohol Dependence 2016, 164: 120-127. PMID: 27207155, PMCID: PMC5592792, DOI: 10.1016/j.drugalcdep.2016.04.037.Peer-Reviewed Original ResearchConceptsMethadone maintenance therapyMaintenance therapyOpioid dependenceDaily heroin useOpioid use disorderLogistic regression analysisMMT initiationDrug use consequencesIndependent correlatesModifiable factorsHIV preventionHeroin useUse disordersParticipant characteristicsMental healthConvenience sampleHIVRegression analysisTherapyStructured questionnaireIncarcerated menMale prisonersUse consequencesLarge proportionPrison populationAttitudes Toward Addiction, Methadone Treatment, and Recovery Among HIV-Infected Ukrainian Prisoners Who Inject Drugs: Incarceration Effects and Exploration of Mediators
Polonsky M, Rozanova J, Azbel L, Bachireddy C, Izenberg J, Kiriazova T, Dvoryak S, Altice FL. Attitudes Toward Addiction, Methadone Treatment, and Recovery Among HIV-Infected Ukrainian Prisoners Who Inject Drugs: Incarceration Effects and Exploration of Mediators. AIDS And Behavior 2016, 20: 2950-2960. PMID: 27011378, PMCID: PMC5035551, DOI: 10.1007/s10461-016-1375-0.Peer-Reviewed Original ResearchConceptsMethadone maintenance therapyGroup 1Drug useGroup 2 participantsDrug addiction severityAwareness of addictionMaintenance therapyMethadone treatmentExploration of mediatorsHIV stigmaGroup 2MMT treatmentAddiction severityGroup comparisonsDrug addictionHIVHigh rateAddictionHigher optimismDrugsTreatmentParticipantsMethadoneGroupPaper’s key findingsAn Exploratory Factor Analysis of a Brief Self-Report Scale to Detect Neurocognitive Impairment Among Participants Enrolled in Methadone Maintenance Therapy
Copenhaver M, Shrestha R, Wickersham JA, Weikum D, Altice FL. An Exploratory Factor Analysis of a Brief Self-Report Scale to Detect Neurocognitive Impairment Among Participants Enrolled in Methadone Maintenance Therapy. Journal Of Substance Use And Addiction Treatment 2016, 63: 61-65. PMID: 26879859, PMCID: PMC4775373, DOI: 10.1016/j.jsat.2016.01.002.Peer-Reviewed Original ResearchConceptsMethadone maintenance therapyNeuropsychological Impairment ScaleNeurocognitive impairmentMaintenance therapySex-related HIV risk behaviorsHIV risk behaviorsClinical care settingsNeuro-cognitive impairmentExploratory factor analysisCare settingsImpairment ScaleRisk behaviorsAddiction treatmentBrief self-report scaleImpairmentSelf-report measuresSelf-report scalesPatientsPrincipal axis factoringCognitive functioningTherapyFactor analysisOrthogonal varimax rotationPresent studyPotential utility
1999
Nevirapine induced opiate withdrawal among injection drug users with HIV infection receiving methadone
Altice F, Friedland G, Cooney E. Nevirapine induced opiate withdrawal among injection drug users with HIV infection receiving methadone. AIDS 1999, 13: 957-962. PMID: 10371177, DOI: 10.1097/00002030-199905280-00012.Peer-Reviewed Original ResearchConceptsPharmacokinetic interactionsOpiate withdrawalMethadone levelsWithdrawal symptomsChronic methadone maintenance therapyNon-nucleoside reverse transcriptase inhibitorSubstance abuseInitiation of therapyMethadone maintenance therapyOpiate withdrawal symptomsRetrospective chart reviewSignificant pharmacokinetic interactionsInjection drug usersReverse transcriptase inhibitorHIV therapeutic agentsAntiretroviral therapyMaintenance therapyMethadone doseChart reviewHIV diseaseHIV infectionIncreased doseTranscriptase inhibitorTherapeutic benefitPatients