2021
Willingness to initiate pre-exposure prophylaxis (PrEP) and its use among opioid-dependent individuals in drug treatment
Ni Z, Altice FL, Wickersham JA, Copenhaver MM, DiDomizio EE, Nelson LE, Shrestha R. Willingness to initiate pre-exposure prophylaxis (PrEP) and its use among opioid-dependent individuals in drug treatment. Drug And Alcohol Dependence 2021, 219: 108477. PMID: 33422864, PMCID: PMC7946167, DOI: 10.1016/j.drugalcdep.2020.108477.Peer-Reviewed Original ResearchConceptsOpioid-dependent individualsPre-exposure prophylaxisPrEP useHIV riskHealthcare providersSex-related risk behaviorsMultivariable logistic regression analysisAwareness of PrEPUrban methadone clinicMultiple logistic regressionDisproportionate HIV burdenLogistic regression analysisCross-sectional surveyHIV burdenHIV infectionHIV testingIndependent correlatesMethadone clinicsDrug treatmentRisk behaviorsLogistic regressionPrEPPrevious useHigher likelihoodProphylaxis
2017
Developing an Integrated, Brief Biobehavioral HIV Prevention Intervention for High-Risk Drug Users in Treatment: The Process and Outcome of Formative Research
Shrestha R, Altice F, Karki P, Copenhaver M. Developing an Integrated, Brief Biobehavioral HIV Prevention Intervention for High-Risk Drug Users in Treatment: The Process and Outcome of Formative Research. Frontiers In Immunology 2017, 8: 561. PMID: 28553295, PMCID: PMC5425476, DOI: 10.3389/fimmu.2017.00561.Peer-Reviewed Original ResearchNeurocognitive impairmentHigh-risk drug usersBehavioral interventionsHigh-risk PWUDHIV prevention behavioral interventionBiobehavioral approachHIV risk reductionHIV prevention interventionsDrug treatment settingsFormative researchHIV prevention effortsTarget populationPrEP adherencePrEP uptakeRisk reduction outcomesHIV preventionDrug treatmentPrevention interventionsFocus groupsTreatment settingsDrug usersRecovery programStructured focus groupsRisk behaviorsTarget population members
2015
Drug Treatment as HIV Prevention Among Women and Girls Who Inject Drugs From a Global Perspective
Springer SA, Larney S, Alam-mehrjerdi Z, Altice FL, Metzger D, Shoptaw S. Drug Treatment as HIV Prevention Among Women and Girls Who Inject Drugs From a Global Perspective. JAIDS Journal Of Acquired Immune Deficiency Syndromes 2015, 69: s155-s161. PMID: 25978482, PMCID: PMC4443704, DOI: 10.1097/qai.0000000000000637.Peer-Reviewed Original ResearchConceptsMedication-assisted therapyDrug treatmentAntiretroviral therapyHIV transmission riskNew HIV infectionsHarm reduction servicesSubstance use disordersPoor treatment accessImplementation of interventionsOpioid useHIV infectionEvidence-based practiceHIV preventionOpioid addictionTreatment accessUse disordersReduction servicesSexual riskTransmission riskTherapyWomenTreatmentDrugsImpressive lackSignificant reduction
2013
Contribution of Substance Use Disorders on HIV Treatment Outcomes and Antiretroviral Medication Adherence Among HIV-Infected Persons Entering Jail
Chitsaz E, Meyer JP, Krishnan A, Springer SA, Marcus R, Zaller N, Jordan AO, Lincoln T, Flanigan TP, Porterfield J, Altice FL. Contribution of Substance Use Disorders on HIV Treatment Outcomes and Antiretroviral Medication Adherence Among HIV-Infected Persons Entering Jail. AIDS And Behavior 2013, 17: 118-127. PMID: 23673792, PMCID: PMC3818019, DOI: 10.1007/s10461-013-0506-0.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAlcohol DrinkingAnti-Retroviral AgentsComorbidityCross-Sectional StudiesFemaleHIV InfectionsHumansLogistic ModelsMaleMedication AdherenceMiddle AgedPrisonersPrisonsSocioeconomic FactorsSubstance Abuse, IntravenousSubstance-Related DisordersTreatment OutcomeUnited StatesYoung AdultConceptsAntiretroviral medication adherenceSubstance use disordersMedication adherenceUse disordersEvidence-based drug treatmentHIV care providersHIV treatment engagementHIV treatment outcomesMedication-assisted therapyMulti-faceted interventionPaucity of evidenceDrug use severityAntiretroviral therapyPoor outcomePsychiatric comorbidityHIV treatmentTreatment outcomesDrug treatmentCare providersJail detaineesTreatment engagementUS sitesSubstance useVulnerable populationsUse severity
2010
Prevalence and correlates of community re-entry challenges faced by HIV-infected male prisoners in Malaysia
Choi P, Kavasery R, Desai MM, Govindasamy S, Kamarulzaman A, Altice FL. Prevalence and correlates of community re-entry challenges faced by HIV-infected male prisoners in Malaysia. International Journal Of STD & AIDS 2010, 21: 416-423. PMID: 20606222, PMCID: PMC2925151, DOI: 10.1258/ijsa.2009.009180.Peer-Reviewed Original Research
2009
Depression and symptomatic response among HIV-infected drug users enrolled in a randomized controlled trial of directly administered antiretroviral therapy
Springer SA, Chen S, Altice F. Depression and symptomatic response among HIV-infected drug users enrolled in a randomized controlled trial of directly administered antiretroviral therapy. AIDS Care 2009, 21: 976-983. PMID: 20024753, PMCID: PMC2797133, DOI: 10.1080/09540120802657555.Peer-Reviewed Original ResearchConceptsInjection drug usersCES-D scoresMajor depressive disorderAntiretroviral therapyCD4 countDepressive symptomsDrug usersDrug useHIV-1 RNA levelsProspective clinical trialsSubstance abuse treatment servicesSelf-administered therapyActive drug useNon-Caucasian raceSix-month followSix-month dataAntidepressant medicationAntiretroviral treatmentPoor adherenceSymptomatic responseMale genderClinical trialsDepressive disorderDepression ScaleDrug treatment
2005
Managing HIV/AIDS in correctional settings
Springer SA, Altice FL. Managing HIV/AIDS in correctional settings. Current HIV/AIDS Reports 2005, 2: 165-170. PMID: 16343373, DOI: 10.1007/s11904-005-0011-9.Peer-Reviewed Original ResearchConceptsHIV/AIDSHIV care sitesActive antiretroviral therapyBurden of infectionEffective drug treatmentHIV risk behaviorsQuarter of peopleCorrectional health care systemIllicit drug useEffective case managementUntreated mental illnessHealth care systemPublic health officialsCorrectional settingsAntiretroviral therapyAdherence strategiesHIV outcomesComorbid conditionsManaging HIV/AIDSEffective therapyHIV epidemicHigh prevalenceCare sitesDrug treatmentHIV detection
2003
Pilot study to enhance HIV care using needle exchange-based health services for out-of-treatment injecting drug users
Altice FL, Springer S, Buitrago M, Hunt DP, Friedland GH. Pilot study to enhance HIV care using needle exchange-based health services for out-of-treatment injecting drug users. Journal Of Urban Health 2003, 80: 416-427. PMID: 12930880, PMCID: PMC3455979, DOI: 10.1093/jurban/jtg053.Peer-Reviewed Original ResearchConceptsHuman immunodeficiency virusNondetectable viral loadCD4 lymphocyte countDrug treatmentDrug usersLymphocyte countViral loadHIV therapyBaseline HIV-1 RNA levelsNeedle exchangeHealth servicesHIV-1 RNA levelsPilot studyPotent antiretroviral combinationUtilization of HAARTActive antiretroviral therapyAntiretroviral therapy regimensHIV-1 RNACommunity-based health interventionsAdverse side effectsActive drug usersFormal drug treatmentImmunodeficiency syndrome (AIDS) incidenceSmall pilot studyActive heroin injectorsSafer Injection Sites in New York City: A Utilization Survey of Injection Drug Users
Broadhead R, Borch C, van Hulst Y, Farrell J, Villemez W, Altice F. Safer Injection Sites in New York City: A Utilization Survey of Injection Drug Users. Journal Of Drug Issues 2003, 33: 733-750. DOI: 10.1177/002204260303300311.Peer-Reviewed Original ResearchInjection drug usersSafe injection sitesDrug overdoseSample of IDUsDrug usersInjection siteDrug-related health problemsBlood-borne diseasesInnovative public health interventionsPublic health interventionsHarm Reduction ProjectHepatitis BDental servicesDrug treatmentPre-obtained drugsHigh riskHealth personnelHealth problemsHealth interventionsSignificant health riskSexual partnersNew York CityReferral servicesStreet outreachNew interventions
2002
Increasing drug users’ adherence to HIV treatment: results of a peer-driven intervention feasibility study
Broadhead RS, Heckathorn DD, Altice FL, van Hulst Y, Carbone M, Friedland GH, O’Connor P, Selwyn PA. Increasing drug users’ adherence to HIV treatment: results of a peer-driven intervention feasibility study. Social Science & Medicine 2002, 55: 235-246. PMID: 12144138, DOI: 10.1016/s0277-9536(01)00167-8.Peer-Reviewed Original ResearchConceptsActive drug usersDrug users' adherenceDrug usersDrug treatmentMedical carePrimary careIntervention feasibility studySocial support structuresHealth advocatesUser adherenceTreatment program staffPeer-driven interventionHIV diseaseHIV infectionPatient adherenceSix-month studyHIV treatmentPhysician referralClinical appointmentsHIV therapeuticsCarePositive behavioral changesAdherencePeer pressureTreatmentThe Impact of Needle Exchange–based Health Services on Emergency Department Use
Pollack HA, Khoshnood K, Blankenship KM, Altice FL. The Impact of Needle Exchange–based Health Services on Emergency Department Use. Journal Of General Internal Medicine 2002, 17: 341-348. PMID: 12047730, PMCID: PMC1495047, DOI: 10.1046/j.1525-1497.2002.10663.x.Peer-Reviewed Original ResearchConceptsInjection drug usersTreatment injection drug usersEmergency department useIncidence rate ratiosED utilizationED useDepartment useDrug usersHigh-risk injection drug usersHIV-negative injection drug usersMobile health clinicHealth care delivery systemHealth care servicesCare delivery systemHIV/AIDSPre-post comparisonAcute careEmergency departmentSubgroup analysisMedical recordsHealth clinicsLongitudinal cohortDrug treatmentED servicesBinomial regression analysisThe impact of needle exchange-based health services on emergency department use
Pollack H, Khoshnood K, Blankenship K, Altice F. The impact of needle exchange-based health services on emergency department use. Journal Of General Internal Medicine 2002, 17: 341-348. DOI: 10.1007/s11606-002-0037-2.Peer-Reviewed Original ResearchInjection drug usersTreatment injection drug usersEmergency department useIncidence rate ratiosED utilizationED useDepartment useDrug usersHigh-risk injection drug usersHIV-negative injection drug usersMobile health clinicHealth care delivery systemHealth care servicesCare delivery systemHIV/AIDSPre-post comparisonAcute careEmergency departmentSubgroup analysisMedical recordsHealth clinicsLongitudinal cohortDrug treatmentED servicesBinomial regression analysisSafer Injection Facilities in North America: Their Place in Public Policy and Health Initiatives
Broadhead R, Kerr T, Grund J, Altice F. Safer Injection Facilities in North America: Their Place in Public Policy and Health Initiatives. Journal Of Drug Issues 2002, 32: 329-355. DOI: 10.1177/002204260203200113.Peer-Reviewed Original ResearchSafer injection facilityHealth initiativesDrug treatmentInjection-related health problemsNeedle exchange programsDrug-using communityPublic health initiativesPublic health programsHealth care programsDrug injectionDrug overdoseDrug injectorsMortality rateCare programNeedle exchangeHealth problemsMedical careHealth programsInjection facilitiesInnovative interventionsTimely contactTreatmentHCVHIVOverdose
1998
Evaluation of an Innovative Program to Address the Health and Social Service Needs of Drug-Using Women with or at Risk for HIV Infection
Thompson A, Blankenship K, Selwyn P, Khoshnood K, Lopez M, Balacos K, Altice F. Evaluation of an Innovative Program to Address the Health and Social Service Needs of Drug-Using Women with or at Risk for HIV Infection. Journal Of Community Health 1998, 23: 419-440. PMID: 9824792, DOI: 10.1023/a:1018706107776.Peer-Reviewed Original ResearchConceptsUnmet service needsDrug-using womenCase management interventionHIV infectionSocial service needsCase managementService needsHigh-risk womenHIV risk behaviorsICM interventionNeedle exchange sitesTreatment drug usersDental servicesMental health counselingDrug treatmentUnmet needDrug usersMedical careHealth counselingRisk behaviorsStreet outreachManagement interventionsCase managersWomenInfection