2023
Randomized trial of exercise on cancer‐related blood biomarkers and survival in women with ovarian cancer
Cartmel B, Li F, Zhou Y, Gottlieb L, Lu L, Mszar R, Harrigan M, Ligibel J, Gogoi R, Schwartz P, Risch H, Irwin M. Randomized trial of exercise on cancer‐related blood biomarkers and survival in women with ovarian cancer. Cancer Medicine 2023, 12: 15492-15503. PMID: 37269192, PMCID: PMC10417064, DOI: 10.1002/cam4.6187.Peer-Reviewed Original ResearchConceptsExercise interventionOvarian cancerTrial of exerciseExercise-induced changesMin/weekGroup differencesSubset of participantsCause mortalityExercise groupOverall survivalStudy armsCA 125Randomized trialsBlood biomarkersBlood drawBreast cancerClinical significanceIGF-1Effect model analysisSecondary analysisBeneficial effectsCancerBiomarkersTrialsWomen
2020
Skin carotenoids are inversely associated with adiposity in breast cancer survivors
Cartmel B, Anderson C, Irwin ML, Harrigan M, Sanft T, Li F, Gellermann W, Ermakov IV, Ferrucci LM. Skin carotenoids are inversely associated with adiposity in breast cancer survivors. Nutrition Research 2020, 79: 77-86. PMID: 32650223, PMCID: PMC7409553, DOI: 10.1016/j.nutres.2020.05.012.Peer-Reviewed Original ResearchConceptsBreast cancer survivorsSkin carotenoid scoreUsual care groupCancer survivorsSkin carotenoidsBody fatCare groupSerum biomarkersAdiposity measuresLog C-reactive protein levelsBaseline percent body fatObese breast cancer survivorsC-reactive protein levelsDual-energy X-ray absorptiometryStrong associationBreast cancer patientsWeight loss trialStudy of overweightTotal body fatPercent body fatX-ray absorptiometryLog leptinPoor outcomeCancer patientsHip circumference
2017
Leptin Is Produced by Parathyroid Glands and Stimulates Parathyroid Hormone Secretion
Hoang D, Broer N, Sosa JA, Abitbol N, Yao X, Li F, Rivera-Molina F, Toomre DK, Roman SA, Sue G, Kim S, Li AY, Callender GG, Simpson C, Narayan D. Leptin Is Produced by Parathyroid Glands and Stimulates Parathyroid Hormone Secretion. Annals Of Surgery 2017, 266: 1075-1083. PMID: 27611607, DOI: 10.1097/sla.0000000000002004.Peer-Reviewed Original ResearchConceptsParathyroid hormone secretionParathyroid glandsHormone secretionLeptin receptorOb/ob miceDiseased parathyroid glandsDiseased parathyroid tissueDiagnosis of hyperparathyroidismParathyroid chief cellsCultured parathyroid cellsAnimal model assaysJAK2/STAT3 inhibitorPTH levelsPTH secretionPTH releaseSerum calciumSitu hybridizationLeptin uptakeProspective studySurgical interventionConfocal microscopyHyperplastic glandsParathyroid tissueBone metabolismOb mice
2013
Leptin Signaling and Hyperparathyroidism: Clinical and Genetic Associations
Hoang D, Broer N, Roman SA, Yao X, Abitbol N, Li F, Sosa JA, Sue GR, DeWan AT, Wong ML, Licinio J, Simpson C, Li AY, Pizzoferrato N, Narayan D. Leptin Signaling and Hyperparathyroidism: Clinical and Genetic Associations. Journal Of The American College Of Surgeons 2013, 218: 1239-1250.e4. PMID: 24468228, DOI: 10.1016/j.jamcollsurg.2013.11.013.Peer-Reviewed Original ResearchConceptsParathyroid hormone levelsLeptin levelsParathyroid glandsHormone levelsBaseline leptin levelsLarge parathyroid glandsBody mass indexRole of leptinWilcoxon signed-rank testHyperplasia subgroupsParathyroid sizeObese patientsPostoperative changesMass indexParathyroid adenomaProspective studyParathyroid tissueBland-Altman methodLeptin productionSigned-rank testSurgical conditionsClinical studiesLeptin signalingLEPR polymorphismsLeptin