2001
Effect of Tick Removal on Transmission of Borrelia burgdorferi and Ehrlichia phagocytophila by Ixodes scapularis Nymphs
Vignes F, Piesman J, Heffernan R, Schulze T, Stafford K, Fish D. Effect of Tick Removal on Transmission of Borrelia burgdorferi and Ehrlichia phagocytophila by Ixodes scapularis Nymphs. The Journal Of Infectious Diseases 2001, 183: 773-778. PMID: 11181154, DOI: 10.1086/318818.Peer-Reviewed Original ResearchConceptsEhrlichia phagocytophilaBorrelia burgdorferiLyme disease endemic areaHuman granulocytic ehrlichiosisDisease-endemic areasScapularis nymphsPolymerase chain reaction analysisSerologic testingField strainsChain reaction analysisSpirochete Borrelia burgdorferiIxodes scapularis nymphsTick removalProbability of infectionHuman infectionsE. phagocytophilaGranulocytic ehrlichiosisInfectionI. scapularis nymphsB. burgdorferiBurgdorferiMiceLyme disease spirochete Borrelia burgdorferiNymphal Ixodes scapularisFed ticks
1997
Transmission of the Agent of Human Granulocytic Ehrlichiosis by Host-Seeking Ixodus scapularis (Acari: Ixodidae) in Southern New York State
Vignes F, Fish D. Transmission of the Agent of Human Granulocytic Ehrlichiosis by Host-Seeking Ixodus scapularis (Acari: Ixodidae) in Southern New York State. Journal Of Medical Entomology 1997, 34: 379-382. PMID: 9220669, DOI: 10.1093/jmedent/34.4.379.Peer-Reviewed Original ResearchConceptsHuman granulocytic ehrlichiosisGranulocytic ehrlichiosisXenodiagnostic larvaeUninfected micePolymerase chain reaction analysisI. scapularis ticksChain reaction analysisBlood smearsHGE agentLyme diseaseMiceWhole bloodInfectionScapularis ticksMicroscopic examinationEhrlichiosisBorrelia burgdorferi JohnsonSouthern New York StateReaction analysisAgentsIxodes scapularisNew York StateWestchester CountyI. scapularisNatural fociInhibition of efficient polymerase chain reaction amplification of Borrelia burgdorferi DNA in blood-fed ticks.
Schwartz I, Varde S, Nadelman R, Wormser G, Fish D. Inhibition of efficient polymerase chain reaction amplification of Borrelia burgdorferi DNA in blood-fed ticks. American Journal Of Tropical Medicine And Hygiene 1997, 56: 339-42. PMID: 9129540, DOI: 10.4269/ajtmh.1997.56.339.Peer-Reviewed Original ResearchConceptsB. burgdorferi DNABorrelia burgdorferi DNAB. burgdorferiInfection rateB. burgdorferi infectionPolymerase chain reaction analysisUtility of PCRInhibitory substancesBurgdorferi infectionChain reaction analysisPCR analysisPositive PCR signalUnfed ticksPolymerase chain reaction amplificationBlood-feeding ticksChain reaction amplificationTick lysatesEngorged ticksPCR amplificationBlood mealSuch inhibitionBurgdorferiEquivalent cohortsReaction amplificationInhibitors
1996
Suppression of Acute Ixodes scapularis-Induced Borrelia burgdorferi Infection using Tumor Necrosis Factor-α, Interleukin-2, and Interferon-γ
Zeidner N, Dreitz M, Belasco D, Fish D. Suppression of Acute Ixodes scapularis-Induced Borrelia burgdorferi Infection using Tumor Necrosis Factor-α, Interleukin-2, and Interferon-γ. The Journal Of Infectious Diseases 1996, 173: 187-195. PMID: 8537658, DOI: 10.1093/infdis/173.1.187.Peer-Reviewed Original ResearchMeSH KeywordsAcute DiseaseAnimalsAntibodies, BacterialArachnid VectorsBlotting, WesternBorrelia burgdorferi GroupDNA, BacterialDrug Therapy, CombinationElectrophoresis, Polyacrylamide GelFluorescent Antibody TechniqueImmune ToleranceImmunity, CellularInjections, IntraperitonealInterferon-gammaInterleukin-2IxodesLyme DiseaseMiceMice, Inbred C3HPolymerase Chain ReactionRandom AllocationTumor Necrosis Factor-alphaConceptsTumor necrosis factorNecrosis factorBurgdorferi infectionB. burgdorferiC3H/HeJ miceTick feedingBorrelia burgdorferi infectionB. burgdorferi infectionImmune containmentPolymerase chain reaction analysisCellular immunityCytokine productionIL-2TNF-alphaHeJ miceInterleukin-2IFN-gammaChain reaction analysisDay 21Infection rateWestern blotEar biopsiesProtection rateInfectionBorrelia burgdorferi