1998
Comparison of Two Measures of Human Immunodeficiency Virus (HIV) Type 1 Load in HIV Risk Groups
Lyles C, Vlahov D, Farzadegan H, Astemborski J, Margolick J, Masters B, Schroeder J, Quinn T. Comparison of Two Measures of Human Immunodeficiency Virus (HIV) Type 1 Load in HIV Risk Groups. Journal Of Clinical Microbiology 1998, 36: 3647-3652. PMID: 9817889, PMCID: PMC105256, DOI: 10.1128/jcm.36.12.3647-3652.1998.Peer-Reviewed Original ResearchConceptsInfectious viral loadInjection drug usersHIV RNA levelsHIV RNA loadViral loadRisk groupsRNA loadViral burdenHuman immunodeficiency virus type 1 (HIV-1) loadHomosexual menPlasma HIV RNA levelsMale injection drug usersFemale injection drug usersHuman immunodeficiency virus type 1Peripheral blood mononuclear cellsImmunodeficiency virus type 1RNA levelsBlood mononuclear cellsHIV risk groupViral RNA loadVirus type 1HIV loadMononuclear cellsDrug usersCell countInfection with Dual-Tropic Human Immunodeficiency Virus Type 1 Variants Associated with Rapid Total T Cell Decline and Disease Progression in Injection Drug Users
Yu X, Wang Z, Vlahov D, Markham R, Farzadegan H, Margolick J. Infection with Dual-Tropic Human Immunodeficiency Virus Type 1 Variants Associated with Rapid Total T Cell Decline and Disease Progression in Injection Drug Users. The Journal Of Infectious Diseases 1998, 178: 388-396. PMID: 9697718, DOI: 10.1086/515646.Peer-Reviewed Original ResearchMeSH KeywordsAdultAmino Acid SequenceCD4 Lymphocyte CountCD4-Positive T-LymphocytesCD8-Positive T-LymphocytesCell LineCells, CulturedDisease ProgressionFemaleGenetic VariationHIV Envelope Protein gp120HIV SeropositivityHIV-1HumansMaleMolecular Sequence DataPeptide FragmentsSequence Homology, Amino AcidSubstance Abuse, IntravenousT-LymphocytesTime FactorsConceptsInjection drug usersSI variantsDisease progressionHuman immunodeficiency virus type 1 variantsDrug usersHuman immunodeficiency virus type 1Immunodeficiency virus type 1HIV-1 transmissionT cell levelsSlow disease progressionT-cell declineDual-tropic virusesType 1 variantsSyncytium-inducing (SI) variantsVirus type 1T cell linesDual tropicNSI variantsSlow progressorsRapid progressionNSI phenotypeT cellsCell declineInitial infectionType 1
1996
Detection of HIV-1 DNA in needle/syringes, paraphernalia, and washes from shooting galleries in Miami: a preliminary laboratory report.
Shah S, Shapshak P, Rivers J, Stewart R, Weatherby N, Xin K, Page J, Chitwood D, Mash D, Vlahov D, McCoy C. Detection of HIV-1 DNA in needle/syringes, paraphernalia, and washes from shooting galleries in Miami: a preliminary laboratory report. JAIDS Journal Of Acquired Immune Deficiency Syndromes 1996, 11: 301-6. PMID: 8603266, DOI: 10.1097/00042560-199603010-00010.Peer-Reviewed Original ResearchConceptsNeedles/syringesHIV-1 DNAInjection drug usersHIV-1 proteinsHIV-1Polymerase chain reactionClean needlesHuman immunodeficiency virus type 1Immunodeficiency virus type 1Act of injectionVirus type 1Injection paraphernaliaPreliminary laboratory reportDrug usersShooting galleriesType 1Western blotReduction of riskEnvelope geneChain reactionGene DNAAntibodiesSyringesLaboratory reportsModification of behavior
1994
Mycarditis and cardiotropic viral infection associated with severe left ventricular dysfunction in late-stage infection with human immunodeficiency virus
Herskowitz A, Wu T, Willoughby S, Vlahov D, Ansari A, Beschorner W, Baughman K. Mycarditis and cardiotropic viral infection associated with severe left ventricular dysfunction in late-stage infection with human immunodeficiency virus. Journal Of The American College Of Cardiology 1994, 24: 1025-1032. PMID: 7930193, DOI: 10.1016/0735-1097(94)90865-6.Peer-Reviewed Original ResearchConceptsLeft ventricular dysfunctionCongestive heart failureEndomyocardial biopsy samplesVentricular dysfunctionHeart failureNew York Heart Association functional class IIIBiopsy samplesGlobal left ventricular hypokinesiaSevere left ventricular dysfunctionUnexplained left ventricular dysfunctionHuman immunodeficiency virus type 1Global left ventricular dysfunctionImmunodeficiency virus type 1Cardiotropic viral infectionCardiotropic virus infectionLeft ventricular hypokinesiaOpportunistic infectious agentFunctional class IIIHuman immunodeficiency virusHIV-1 gene sequencesNumber of patientsTwo-dimensional echocardiographyMajor histocompatibility class IVirus type 1Antisense riboprobesInterest in HIV vaccines among injection drug users in Baltimore, Maryland.
Vlahov D, Astemborski J, Solomon L, Galai N, Basarab L, Nelson K. Interest in HIV vaccines among injection drug users in Baltimore, Maryland. AIDS Research And Human Retroviruses 1994, 10 Suppl 2: s265-8. PMID: 7865315.Peer-Reviewed Original Research
1992
Changes in T-Lymphocyte Subsets in Intravenous Drug Users With HIV-1 Infection
Margolick J, Muñoz A, Vlahov D, Solomon L, Astemborski J, Cohn S, Nelson K. Changes in T-Lymphocyte Subsets in Intravenous Drug Users With HIV-1 Infection. JAMA 1992, 267: 1631-1636. PMID: 1347321, DOI: 10.1001/jama.1992.03480120069035.Peer-Reviewed Original ResearchConceptsSeropositive intravenous drug usersIntravenous drug usersHIV-1 infectionHIV-1-seropositive intravenous drug usersDrug usersCell countSeronegative intravenous drug usersHuman immunodeficiency virus type 1Complete blood cell countImmunodeficiency virus type 1Absolute numberCD4 cell countCD4 lymphocyte countPercentage of CD4T lymphocyte subsetsCD8 T cellsT cell subsetsCommunity-based clinicsBlood cell countTime of seroconversionVirus type 1Multivariate regression analysisUse of drugsCD4 lymphocytesCD8 lymphocytes
1991
New Evidence on Intravenous Cocaine Use and the Risk of Infection with Human Immunodeficiency Virus Type 1
Anthony J, Vlahov D, Nelson K, Conn S, Astemborski J, Solomon L. New Evidence on Intravenous Cocaine Use and the Risk of Infection with Human Immunodeficiency Virus Type 1. American Journal Of Epidemiology 1991, 134: 1175-1189. PMID: 1746528, DOI: 10.1093/oxfordjournals.aje.a116021.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultBaltimoreBiasCausalityCocaineConfounding Factors, EpidemiologicFemaleHealth BehaviorHIV InfectionsHIV SeroprevalenceHIV-1HumansLogistic ModelsMiddle AgedPredictive Value of TestsPrevalenceProspective StudiesSexual BehaviorSubstance Abuse, IntravenousSurveys and QuestionnairesConceptsIntravenous drug usersDrug treatment programsCocaine injectorsDrug usersHIV seroprevalenceHIV infectionHuman immunodeficiency virus type 1 (HIV-1) infectionTreatment programActive intravenous drug usersHuman immunodeficiency virus type 1Virus type 1 infectionImmunodeficiency virus type 1Preliminary prospective dataIntravenous cocaine useType 1 infectionReceptive anal intercourseMultiple logistic regressionRisk of infectionVirus type 1HIV seroconversionPresent studyExcess riskProspective dataIntravenous usePresent study samplePrevalence of Antibody to HIV-1 Among Entrants to US Correctional Facilities
Vlahov D, Brewer T, Castro K, Narkunas J, Salive M, Ullrich J, Muñoz A. Prevalence of Antibody to HIV-1 Among Entrants to US Correctional Facilities. JAMA 1991, 265: 1129-1132. PMID: 1995998, DOI: 10.1001/jama.1991.03460090077036.Peer-Reviewed Original ResearchConceptsPrevalence of antibodiesHuman immunodeficiency virus type 1Immunodeficiency virus type 1HIV-1 prevalenceHIV-1 seroprevalenceAge 25 yearsVirus type 1US correctional facilitiesConsecutive malesHIV-1Older womenOlder menPrevention programsType 1Young womenPrevalenceWomenCorrectional systemYoung menMenSeroprevalenceAntibodiesProgram planningCorrectional facilities
1990
ASSOCIATION OF DRUG INJECTION PATTERNS WITH ANTIBODY TO HUMAN IMMUNODEFICIENCY VIRUS TYPE 1 AMONG INTRAVENOUS DRUG USERS IN BALTIMORE, MARYLAND
VLAHOV D, MUñOZ A, ANTHONY J, COHN S, CELENTANO D, NELSON K. ASSOCIATION OF DRUG INJECTION PATTERNS WITH ANTIBODY TO HUMAN IMMUNODEFICIENCY VIRUS TYPE 1 AMONG INTRAVENOUS DRUG USERS IN BALTIMORE, MARYLAND. American Journal Of Epidemiology 1990, 132: 847-856. PMID: 2239899, DOI: 10.1093/oxfordjournals.aje.a115727.Peer-Reviewed Original ResearchConceptsIntravenous drug usersHuman immunodeficiency virus type 1Immunodeficiency virus type 1HIV-1 seroprevalenceVirus type 1Drug usersInjection careerShooting galleriesType 1Drug injection patternsHIV-1 serostatusHIV-1 infectionRecent onsetDrug injectionHigh riskCommunity outreach effortsDrug useGallery useSame calendar yearSex practicesSeroprevalenceCalendar yearPersistent useAntibodiesPersistent sharingCoinfection with tuberculosis and HIV-1 in male prison inmates.
Salive M, Vlahov D, Brewer T. Coinfection with tuberculosis and HIV-1 in male prison inmates. Public Health Reports 1990, 105: 307-10. PMID: 2113691, PMCID: PMC1580008.Peer-Reviewed Original ResearchConceptsHIV-1HIV-1 antibody testingHuman immunodeficiency virus type 1Latent HIV-1 infectionImmunodeficiency virus type 1HIV-1 infectionVirus type 1Case-control designAnergy testingTB infectionAntibody testingMantoux testingElevated riskSignificant associationPast exposureTuberculosisType 1InfectionState prison systemMale prison inmatesAssociationPrison inmatesMale inmatesIntake samplesAdmission
1989
Temporal trends of human immunodeficiency virus type 1 (HIV-1) infection among inmates entering a statewide prison system, 1985-1987.
Vlahov D, Brewer F, Muñoz A, Hall D, Taylor E, Polk B. Temporal trends of human immunodeficiency virus type 1 (HIV-1) infection among inmates entering a statewide prison system, 1985-1987. JAIDS Journal Of Acquired Immune Deficiency Syndromes 1989, 2: 283-90. PMID: 2786071.Peer-Reviewed Original ResearchConceptsIntravenous drug usersHuman immunodeficiency virus type 1 (HIV-1) infectionHuman immunodeficiency virus type 1Virus type 1 infectionImmunodeficiency virus type 1Incoming male inmatesHIV-1 seroprevalenceIntravenous drug useType 1 infectionImmune deficiency syndromeCause of deathRisk of infectionVirus type 1Drug use variablesWestern blot techniqueCrude prevalenceRisk factorsUnivariate analysisDeficiency syndromeHIV-1Temporal trendsDrug usersDrug useExcess serumIncoming inmates