2015
Prioritizing HIV comparative effectiveness trials based on value of information: generic versus brand-name ART in the US
Pei PP, Weinstein MC, Li XC, Hughes MD, Paltiel AD, Hou T, Parker RA, Gaynes MR, Sax PE, Freedberg KA, Schackman BR, Walensky RP. Prioritizing HIV comparative effectiveness trials based on value of information: generic versus brand-name ART in the US. HIV Research & Clinical Practice 2015, 16: 207-218. PMID: 26651525, PMCID: PMC4718767, DOI: 10.1080/15284336.2015.1123942.Peer-Reviewed Original ResearchMeSH KeywordsAnti-HIV AgentsClinical Trials as TopicCost-Benefit AnalysisDrug CostsDrugs, GenericHIV InfectionsHumansModels, EconomicUnited StatesConceptsGeneric antiretroviral therapyAntiretroviral therapyProbabilistic sensitivity analysesTreatment changesFirst-line ART regimensMore treatment changesComparative effectiveness trialTwo-arm trialImproved health outcomesTwo-pillART regimensHIV careART failureEffectiveness trialTrial completionRNA suppressionHealth outcomesFuture patientsPatientsCost-effective strategyTrialsRegimenRegimensHIVTherapy
2011
Resource Utilization and Cost-Effectiveness of Counselor- vs. Provider-Based Rapid Point-of-Care HIV Screening in the Emergency Department
Walensky RP, Morris BL, Reichmann WM, Paltiel AD, Arbelaez C, Donnell-Fink L, Katz JN, Losina E. Resource Utilization and Cost-Effectiveness of Counselor- vs. Provider-Based Rapid Point-of-Care HIV Screening in the Emergency Department. PLOS ONE 2011, 6: e25575. PMID: 22022415, PMCID: PMC3192047, DOI: 10.1371/journal.pone.0025575.Peer-Reviewed Original ResearchConceptsQuality-adjusted life yearsIncremental cost-effectiveness ratioUndiagnosed HIV prevalenceEmergency department settingCost-effectiveness ratioHIV prevalenceDepartment settingScreening modalityRandomized clinical trialsResource utilization dataRoutine HIVHIV screeningHIV counselorsEmergency departmentScreening servicesClinical trialsCapacity of providersScreening programED staffHIVTest offerLife yearsUtilization dataRapid pointPrevalenceThe potential impact of an HIV vaccine with rapidly waning protection on the epidemic in Southern Africa: Examining the RV144 trial results
Andersson KM, Paltiel AD, Owens DK. The potential impact of an HIV vaccine with rapidly waning protection on the epidemic in Southern Africa: Examining the RV144 trial results. Vaccine 2011, 29: 6107-6112. PMID: 21736912, PMCID: PMC3164284, DOI: 10.1016/j.vaccine.2011.06.076.Peer-Reviewed Original ResearchConceptsBooster vaccinationHIV prevalencePopulation coverage levelsRV144 trialHIV vaccineCondom useContinuous vaccinationHIV vaccine regimenPopulation HIV prevalenceDuration of protectionCoverage levelsRV144 vaccineVaccine regimenHIV infectionHeterosexual transmissionModest efficacyVaccine efficacyUnvaccinated populationVaccination strategiesPartial efficacyEfficacy vaccineLower riskVaccinationBooster strategyVaccine
2002
A novel approach to defining the relationship between lung function and symptom status in asthma
Kuntz KM, Kitch BT, Fuhlbrigge AL, Paltiel AD, Weiss ST. A novel approach to defining the relationship between lung function and symptom status in asthma. Journal Of Clinical Epidemiology 2002, 55: 11-18. PMID: 11781117, DOI: 10.1016/s0895-4356(01)00412-7.Peer-Reviewed Original ResearchMeSH KeywordsAdultAsthmaClinical Trials as TopicForced Expiratory VolumeHumansLinear ModelsPredictive Value of TestsSeverity of Illness IndexConceptsAsthma-related symptomsLung functionMean lung functionAverage baseline valuePopulation-wide basisExpiratory volumeSymptom daysSymptom scoresNighttime awakeningsSymptom statusClinical trialsMean changeBaseline valuesLinear regression analysisSymptomsRegression analysisNegative associationOverall improvementAssociationAsthmaConsistent relationshipTrials
1993
The epidemiological and economic consequences of AIDS clinical trials.
Paltiel AD, Kaplan EH. The epidemiological and economic consequences of AIDS clinical trials. JAIDS Journal Of Acquired Immune Deficiency Syndromes 1993, 6: 179-90. PMID: 8433283.Peer-Reviewed Original ResearchMeSH KeywordsAcquired Immunodeficiency SyndromeClinical Trials as TopicCost-Benefit AnalysisDecision TreesHumansMalePolicy MakingConceptsClinical trials