2023
Sleep dysfunction mediates the relationship between hypothalamic-insula connectivity and anxiety-depression symptom severity bidirectionally in young adults
Li G, Chen Y, Chaudhary S, Li C, Hao D, Yang L, Li C. Sleep dysfunction mediates the relationship between hypothalamic-insula connectivity and anxiety-depression symptom severity bidirectionally in young adults. NeuroImage 2023, 279: 120340. PMID: 37611815, DOI: 10.1016/j.neuroimage.2023.120340.Peer-Reviewed Original ResearchMeSH KeywordsAnxietyDepressionEmotionsFemaleHumansHypothalamusMaleSleepSleep Wake DisordersYoung AdultConceptsPittsburgh Sleep Quality IndexRight insulaSymptom severityMediation analysisSleep dysfunctionWhole-brain regressionHuman Connectome Project datasetSubjective mood stateYoung adultsState functional connectivityDepression symptom severityNegative emotionsCognitive performanceEmotional deficitsEmotional statesPotential sex differencesAffective functionsDrinking severityMood statesMotivated behaviorFunctional connectivityPoor sleep qualityRSFCSleep Quality IndexSleep quality
2021
Variations in Sleep Characteristics and Glucose Regulation in Young Adults With Type 1 Diabetes
Griggs S, Grey M, Strohl KP, Crawford SL, Margevicius S, Kashyap SR, Li CR, Rajagopalan S, Hickman RL. Variations in Sleep Characteristics and Glucose Regulation in Young Adults With Type 1 Diabetes. The Journal Of Clinical Endocrinology & Metabolism 2021, 107: e1085-e1095. PMID: 34698348, PMCID: PMC8852208, DOI: 10.1210/clinem/dgab771.Peer-Reviewed Original ResearchConceptsHigh glucose variabilityGlucose variability indicesGlucose variabilityType 1 diabetesSleep-wake characteristicsMore sleep disruptionSleep disruptionContinuous glucose monitorPoor sleepYoung adultsShort sleep durationLower sleep efficiencyMajor psychiatric comorbiditiesVariability indexPsychiatric comorbidityDiabetes careSleep characteristicsSleep efficiencyWrist actigraphySleep durationGlucose regulationGlucose patternsImpaired glucoregulationSleep habitsSleep onsetAlcohol use severity and the neural correlates of the effects of sleep disturbance on sustained visual attention
Li G, Chen Y, Tang X, Li CR. Alcohol use severity and the neural correlates of the effects of sleep disturbance on sustained visual attention. Journal Of Psychiatric Research 2021, 142: 302-311. PMID: 34416549, PMCID: PMC8429210, DOI: 10.1016/j.jpsychires.2021.08.018.Peer-Reviewed Original ResearchMeSH KeywordsBrainConnectomeFemaleHumansMagnetic Resonance ImagingSleepSleep Wake DisordersYoung AdultConceptsPittsburgh Sleep Quality IndexNeural correlatesAlcohol useSleep disturbancesReaction timeSustained visual attentionAlcohol misuseWhole-brain regressionGreater sleep disturbanceHuman Connectome ProjectSevere alcohol useVisual attentionSustained attentionNeural processesCognitive performanceLow accuracy rateLonger reaction timesPerformance accuracyConnectome Project