2020
Common and gender‐specific associations with cocaine use on gray matter volume: Data from the ENIGMA addiction working group
Rabin RA, Mackey S, Parvaz MA, Cousijn J, Li C, Pearlson G, Schmaal L, Sinha R, Stein E, Veltman D, Thompson PM, Conrod P, Garavan H, Alia‐Klein N, Goldstein RZ. Common and gender‐specific associations with cocaine use on gray matter volume: Data from the ENIGMA addiction working group. Human Brain Mapping 2020, 43: 543-554. PMID: 32857473, PMCID: PMC8675419, DOI: 10.1002/hbm.25141.Peer-Reviewed Original ResearchConceptsGray matter volumeCocaine useCocaine-dependent individualsMatter volumeCD individualsWhole-brain linear regressionAnterior insulaHippocampal gray matter volumeSelect brain areasT1-weighted MRI scansGender-specific associationsTotal intracranial volumeENIGMA Addiction Working GroupCue-induced cravingLeft anterior insulaGender-specific mechanismsAge-matched participantsCD menCD womenVoxel-based morphometry dataControl menLimbic regionsClinical dataMRI scansBrain areas
2016
Chapter 24 Cerebral Gray Matter Volumes in Cocaine Dependence Clinical and Functional Implications
Li C. Chapter 24 Cerebral Gray Matter Volumes in Cocaine Dependence Clinical and Functional Implications. 2016, 245-256. DOI: 10.1016/b978-0-12-800212-4.00024-8.Peer-Reviewed Original ResearchGray matter volumeCerebral gray matter volumeSuperior frontal gyrusHealthy controlsMatter volumeCingulate cortexCD individualsMiddle/posterior cingulate cortexRight superior frontal gyrusBilateral superior frontal gyrusLoss of neuronsDuration of useVoxel-based morphometryRight ventral putamenMagnetic resonance imagingMultiple brain regionsPosterior cingulate cortexAffective functionsCerebral morphometryVasoactive effectsGMV lossVentral putamenCocaine-dependent individualsTemporal cortexCocaine abuse
2013
Cerebral gray matter volumes and low-frequency fluctuation of BOLD signals in cocaine dependence: Duration of use and gender difference
Ide JS, Zhang S, Hu S, Sinha R, Mazure CM, Li CS. Cerebral gray matter volumes and low-frequency fluctuation of BOLD signals in cocaine dependence: Duration of use and gender difference. Drug And Alcohol Dependence 2013, 134: 51-62. PMID: 24090712, PMCID: PMC3865077, DOI: 10.1016/j.drugalcdep.2013.09.004.Peer-Reviewed Original ResearchConceptsGray matter volumeSuperior frontal gyrusDuration of useGM volumeMatter volumeLow-frequency fluctuationsBOLD signalCingulate cortexCD individualsCocaine useCerebral gray matter volumeAlcohol useMiddle/posterior cingulate cortexRight superior frontal gyrusGM volume lossBilateral superior frontal gyrusHealthy control subjectsRight ventral putamenMagnetic resonance imagingChronic cocaine usePosterior cingulate cortexInfluence of ageEffect of ageControl subjectsVentral putamenMethylphenidate remediates error-preceding activation of the default mode brain regions in cocaine-addicted individuals
Matuskey D, Luo X, Zhang S, Morgan PT, Abdelghany O, Malison RT, Li CS. Methylphenidate remediates error-preceding activation of the default mode brain regions in cocaine-addicted individuals. Psychiatry Research 2013, 214: 116-121. PMID: 23973363, PMCID: PMC3811038, DOI: 10.1016/j.pscychresns.2013.06.009.Peer-Reviewed Original ResearchMeSH KeywordsAdultCentral Nervous System StimulantsCerebral CortexCocaine-Related DisordersCognition DisordersFemaleHumansImage Processing, Computer-AssistedInhibition, PsychologicalMagnetic Resonance ImagingMaleMethylphenidateMiddle AgedModels, NeurologicalNeural PathwaysNeuropsychological TestsOxygenPhotic StimulationReaction TimeConceptsFunctional magnetic resonance imagingStop-signal taskCD individualsCerebral activationPrecuneus/posterior cingulate cortexSystolic blood pressureInfluence of methylphenidateEffects of methylphenidateMagnetic resonance imagingPosterior cingulate cortexBrain imaging studiesCocaine-addicted individualsDefault mode networkAgonist therapyBlood pressureIntravenous methylphenidateCortico-striatoHealthy controlsCocaine-dependent individualsThalamic activationCingulate cortexResonance imagingBrain regionsMethylphenidateCocaine dependence