2011
Deficits in default mode network activity preceding error in cocaine dependent individuals
Bednarski SR, Zhang S, Hong KI, Sinha R, Rounsaville BJ, Li CS. Deficits in default mode network activity preceding error in cocaine dependent individuals. Drug And Alcohol Dependence 2011, 119: e51-e57. PMID: 21703783, PMCID: PMC3188675, DOI: 10.1016/j.drugalcdep.2011.05.026.Peer-Reviewed Original ResearchConceptsDefault mode networkCocaine dependenceCocaine useHealthy controlsTask-related cerebral activationBlood oxygenation level-dependent (BOLD) signalDemographics-matched healthy controlsGray matter volumeDefault mode network activityLevel-dependent signalChronic cocaine useRegional brain activationPosterior cingulate cortexStatistical parametric mappingCerebral functionBilateral precuneusCocaine-dependent individualsCerebral activationHealthy peopleMatter volumeCingulate cortexVentromedial prefrontal cortexBrain regionsCognitive deficitsCocaine misuse
2007
Greater activation of the “default” brain regions predicts stop signal errors
Li CS, Yan P, Bergquist KL, Sinha R. Greater activation of the “default” brain regions predicts stop signal errors. NeuroImage 2007, 38: 640-648. PMID: 17884586, PMCID: PMC2097963, DOI: 10.1016/j.neuroimage.2007.07.021.Peer-Reviewed Original ResearchConceptsSignal taskBehavioral adjustmentBrain regionsPost-error behavioral adjustmentCingulate cortexMidline brain regionsStop-signal taskPerigenual anterior cingulate cortexSignal detection theoryPosterior cingulate cortexAnterior cingulate cortexCortical brain regionsCognitive tasksStop successElicit errorsError processingNeural processesStop errorFMRI studyMental effortGreater activationPerformance errorsDetection theoryBilateral precuneusTask