2004
Validation of Insulin Sensitivity Indices from Oral Glucose Tolerance Test Parameters in Obese Children and Adolescents
Yeckel CW, Weiss R, Dziura J, Taksali SE, Dufour S, Burgert TS, Tamborlane WV, Caprio S. Validation of Insulin Sensitivity Indices from Oral Glucose Tolerance Test Parameters in Obese Children and Adolescents. The Journal Of Clinical Endocrinology & Metabolism 2004, 89: 1096-1101. PMID: 15001593, DOI: 10.1210/jc.2003-031503.Peer-Reviewed Original ResearchConceptsWhole-body insulin sensitivity indexOral glucose tolerance testInsulin sensitivity indexIntramyocellular lipid contentInsulin sensitivityInsulin resistanceObese youthLarge cohortComposite whole body insulin sensitivity indexOral glucose tolerance test parametersSurrogate indexClamp-derived insulin sensitivityImpaired glucose toleranceGlucose tolerance testType 2 diabetesEuglycemic hyperinsulinemic clampInsulin sensitivity measurementsGlucose toleranceMetabolic syndromeObese childrenObese populationPoor functionPlasma glucoseTolerance testInsulin response
2000
Fat metabolism during high-intensity exercise in endurance-trained and untrained men
Coggan A, Raguso C, Gastaldelli A, Sidossis L, Yeckel C. Fat metabolism during high-intensity exercise in endurance-trained and untrained men. Metabolism 2000, 49: 122-128. PMID: 10647075, DOI: 10.1016/s0026-0495(00)90963-6.Peer-Reviewed Original ResearchConceptsHigh-intensity exerciseFree fatty acidsFatty acid oxidationUntrained menIntramuscular triglyceride storesPlasma FFA fluxEndurance-trained menMinutes of exerciseFatty acidsMaximal oxygen consumptionWhole body rateTotal energy expenditureAcid oxidationFFA fluxFFA utilizationIntense exerciseIndirect calorimetryAdditional fatty acidsAdipose tissueFat metabolismTriglyceride storesRate of appearanceUntrained subjectsEnergy expenditureUntrained individuals