2017
Impact of hearing and visual impairment in older adults with cancer.
Soto Perez De Celis E, Sun C, Tew W, Mohile S, Gajra A, Klepin H, Owusu C, Gross C, Muss H, Lichtman S, Chapman A, Cohen H, Dale W, Kim H, Katheria V, Hurria A. Impact of hearing and visual impairment in older adults with cancer. Journal Of Clinical Oncology 2017, 35: 10036-10036. DOI: 10.1200/jco.2017.35.15_suppl.10036.Peer-Reviewed Original ResearchCognitive deficitsOlder adultsImpact of hearingVisual impairmentIADL dependencyImpaired hearingAnxietyDaily livingDeficitsInstrumental activitiesImpairmentDepressionHearingCross-sectional analysisAdultsChemotherapy toxicityOlder patientsProspective studyRisk factorsADL limitationsHigh riskSolid tumorsMultivariate analysisCancerRiskRisk factors for hospitalizations (HOS) among older adults with gastrointestinal (GI) cancers receiving chemotherapy.
Li D, Sun C, Levi A, Klepin H, Elias R, Mohile S, Tew W, Lim D, Chung V, Chao J, Owusu C, Muss H, Lichtman S, Gross C, Chapman A, Gajra A, Cohen H, Katheria V, Hurria A. Risk factors for hospitalizations (HOS) among older adults with gastrointestinal (GI) cancers receiving chemotherapy. Journal Of Clinical Oncology 2017, 35: e21523-e21523. DOI: 10.1200/jco.2017.35.15_suppl.e21523.Peer-Reviewed Original ResearchGI cancersRisk factorsCardiac comorbiditiesOlder adultsGeriatric assessmentOdds ratioLow serum albuminStage IV diseaseIncidence of hospitalizationRisk of hospitalizationAdults age 65Days post treatmentChemotherapy typePatient agePatient characteristicsProspective studyFemale sexGastrointestinal cancerChemotherapy treatmentUnivariate analysisLaboratory valuesHospitalizationChemotherapyMultivariate analysisPatients
2012
Anemia and functional disability in older adults with cancer.
Owusu C, Tew W, Hardt M, Mohile S, Klepin H, Gross C, Gajra A, Lichtman S, Ramani R, Katheria V, Zavala L, Hurria A. Anemia and functional disability in older adults with cancer. Journal Of Clinical Oncology 2012, 30: 9109-9109. DOI: 10.1200/jco.2012.30.15_suppl.9109.Peer-Reviewed Original ResearchFunctional disabilityProspective studyOlder adultsMulti-center prospective studyUnintentional weight lossCorrection of anemiaRandomized-controlled trialPre-treatment variablesOlder ptsChemotherapy toxicityGeriatric assessmentPatient agePrimary outcomeMean HbFunctional statusInstrumental activitiesDaily livingAnemiaAdvanced stageMultivariate analysisAge 65Secondary analysisModifiable strategiesBivariate analysisLogistic regressionPredictors of early discontinuation of chemotherapy (EDC) in patients (pts) age 65 or older with stage IV non-small cell lung cancer (NSCLC).
Gajra A, Tew W, Hardt M, Mohile S, Owusu C, Klepin H, Gross C, Lichtman S, Katheria V, Hurria A. Predictors of early discontinuation of chemotherapy (EDC) in patients (pts) age 65 or older with stage IV non-small cell lung cancer (NSCLC). Journal Of Clinical Oncology 2012, 30: e18133-e18133. DOI: 10.1200/jco.2012.30.15_suppl.e18133.Peer-Reviewed Original ResearchStage IV non-small cell lung cancerNon-small cell lung cancerPoor physical functionOlder ptsPhysical functionAge 65Multi-site prospective studyBivariate analysisGeriatric assessment variablesPatients age 65Cell lung cancerMultivariate logistic regressionLower mean HbPt ageChemotherapy toxicityEarly discontinuationAlbumin levelsMean HbProspective studyPoor outcomeHigher cancerLung cancerPhysical scoresSubset analysisDisease progression