2023
The role of exposure to per- and polyfluoroalkyl substances in racial/ethnic disparities in hypertension: Results from the study of Women's health across the nation
Ding N, Karvonen-Gutierrez C, Zota A, Mukherjee B, Harlow S, Park S. The role of exposure to per- and polyfluoroalkyl substances in racial/ethnic disparities in hypertension: Results from the study of Women's health across the nation. Environmental Research 2023, 227: 115813. PMID: 37004857, PMCID: PMC10227830, DOI: 10.1016/j.envres.2023.115813.Peer-Reviewed Original ResearchStudy of Women's HealthRacial/ethnic disparitiesWomen's HealthIncident hypertensionMidlife womenSerum PFAS concentrationsHypertension onsetModifiable risk factorsAnnual follow-up visitsCausal mediation analysisContribution of environmental pollutionPublic health problemAssociated with hypertensionRacial/ethnic differencesPFAS exposureBlack participantsWhite participantsFollow-up visitG-computationQuantile-based g-computationWhite womenHealth problemsPFAS concentrationsExposure to per-Disparities
2021
Bayesian Sparse Mediation Analysis with Targeted Penalization of Natural Indirect Effects
Song Y, Zhou X, Kang J, Aung M, Zhang M, Zhao W, Needham B, Kardia S, Liu Y, Meeker J, Smith J, Mukherjee B. Bayesian Sparse Mediation Analysis with Targeted Penalization of Natural Indirect Effects. Journal Of The Royal Statistical Society Series C (Applied Statistics) 2021, 70: 1391-1412. PMID: 34887595, PMCID: PMC8653861, DOI: 10.1111/rssc.12518.Peer-Reviewed Original ResearchNatural indirect effectMulti-Ethnic Study of AtherosclerosisMediation analysisMediator-outcome effectsMulti-Ethnic StudyStudy of AtherosclerosisCausal mediation analysisLIFECODES birth cohortBirth cohortEpidemiological studiesJoint prior distributionPotential mediatorsHigh-dimensional mediation analysisGaussian mixtureHigh-dimensional mediatorsIndirect effectsPrior distributionEstimation accuracyExposure-mediated effectsBayesian paradigmExposure effectsAvailability of measurementsComposite structuresIncreasing availability of measurements
2019
Bayesian Shrinkage Estimation of High Dimensional Causal Mediation Effects in Omics Studies
Song Y, Zhou X, Zhang M, Zhao W, Liu Y, Kardia S, Roux A, Needham B, Smith J, Mukherjee B. Bayesian Shrinkage Estimation of High Dimensional Causal Mediation Effects in Omics Studies. Biometrics 2019, 76: 700-710. PMID: 31733066, PMCID: PMC7228845, DOI: 10.1111/biom.13189.Peer-Reviewed Original ResearchConceptsMediation analysisEffect of socioeconomic statusPotential mediatorsMulti-Ethnic StudyCausal mediation analysisCardiometabolic outcomesDNA methylation regionsSocioeconomic statusHigh-throughput technologiesMediation effectGenomic dataEpidemiological dataMethylation regionsHigh-dimensional mediatorsBayesian inference methodsContinuous shrinkage priorsHigh-dimensional settingsBayesian shrinkage estimatorsJoint analysisOutcomesShrinkage priorsPathwayNull caseInference methodsBiomedical studies