2024
Trauma exposure among young children in rural Pakistan: Associations with gender, mental health, and cognitive skills
Frost A, Collins A, Chung E, Escobar Carias M, Hagaman A, Gupta S, Bibi A, Sikander S, Maselko J. Trauma exposure among young children in rural Pakistan: Associations with gender, mental health, and cognitive skills. BMC Psychology 2024, 12: 454. PMID: 39183356, PMCID: PMC11346172, DOI: 10.1186/s40359-024-01944-x.Peer-Reviewed Original ResearchConceptsChild mental healthMental healthLow-resource settingsAssociated with increased mental health difficultiesRural PakistanMental health difficultiesTrauma exposureMental health problemsStrength of associationSample of mother-child dyadsIncreased anxiety scoresChildren's lifetime exposureTrauma-informed interventionsMother-child dyadsCognitive healthAssociated with genderHealth difficultiesBackgroundThe burdenAnxiety scoresHealth problemsHealthLifetime exposureExperience traumaChildren's cognitive skillsCognitive skills
2022
Non-linear associations between HPA axis activity during infancy and mental health difficulties during early childhood among children in rural Pakistan.
Frost A, Hagaman A, Baranov V, Chung EO, Bhalotra S, Sikander S, Maselko J. Non-linear associations between HPA axis activity during infancy and mental health difficulties during early childhood among children in rural Pakistan. Development And Psychopathology 2022, 35: 2086-2095. PMID: 35959681, PMCID: PMC9922341, DOI: 10.1017/s0954579422000773.Peer-Reviewed Original ResearchConceptsHPA axis activityMental health difficultiesAxis activityHealth difficultiesEarly childhoodHypothalamic pituitary adrenal axis activityPituitary-adrenal axis activitySDQ scoresAdrenal axis activityNon-linear associationLongitudinal cohortDepression trialsQuadratic associationHair cortisolDehydroepiandosteroneRural PakistanMental healthCortisolEarly adversitySignificant quadratic associationDifficulties QuestionnaireLow-resource contextsChildhoodChildrenAssociationMother-in-law childcare and perinatal depression in rural Pakistan
Chung E, Hagaman A, Bibi A, Frost A, Haight S, Sikander S, Maselko J. Mother-in-law childcare and perinatal depression in rural Pakistan. Women's Health 2022, 18: 17455057221141288. PMID: 36468464, PMCID: PMC9726850, DOI: 10.1177/17455057221141288.Peer-Reviewed Original ResearchConceptsPerinatal depressionMaternal mental healthMonths postpartumMental healthImmediate postpartum periodFirst year postpartumStructured Clinical InterviewCross-sectional associationsHigh motherMental Disorders-IVYear postpartumLife Events ChecklistPostpartum periodMajor depressionPerinatal periodMaternal depressionLow prevalenceBirth cohortClinical InterviewLow motherPostpartumRural PakistanStatistical ManualDepressionMothers
2021
Passive sensing on mobile devices to improve mental health services with adolescent and young mothers in low-resource settings: the role of families in feasibility and acceptability
Maharjan SM, Poudyal A, van Heerden A, Byanjankar P, Thapa A, Islam C, Kohrt BA, Hagaman A. Passive sensing on mobile devices to improve mental health services with adolescent and young mothers in low-resource settings: the role of families in feasibility and acceptability. BMC Medical Informatics And Decision Making 2021, 21: 117. PMID: 33827552, PMCID: PMC8025381, DOI: 10.1186/s12911-021-01473-2.Peer-Reviewed Original ResearchConceptsINTERNATIONAL REGISTERED REPORT IDENTIFIERHealth servicesMajor modifiable factorsYoung mothersChild health servicesMental health servicesFeasibility challengesLow-resource settingsMaternal-child interactionDepression treatmentModifiable factorsVaccination clinicsPostpartum depressionFamily involvementPhysical activityEligibility criteriaMother-infant proximityMental healthcareGreater family involvementPsychological interventionsMothersDaily activitiesRural NepalInfantsImproved communicationLongitudinal effects of perinatal social support on maternal depression: a marginal structural modelling approach
Hagaman A, LeMasters K, Zivich PN, Sikander S, Bates LM, Bhalotra S, Chung EO, Zaidi A, Maselko J. Longitudinal effects of perinatal social support on maternal depression: a marginal structural modelling approach. Journal Of Epidemiology & Community Health 2021, 75: 936-943. PMID: 33712512, PMCID: PMC8434957, DOI: 10.1136/jech-2020-215836.Peer-Reviewed Original ResearchConceptsMaternal Social Support IndexMonths postpartumPerinatal periodMaternal depressionProtective effectSocial supportCohort of womenMajor depressive disorderStructured Clinical InterviewYear of childbirthSubsequent maternal depressionComplex bidirectional relationshipSustained social supportFuture depressive episodesSocial Support IndexMarginal structural modelsPerinatal depressionThird trimesterDecreased riskImportant protective factorDepressive episodeDepressive disorderPostpartum depressionHigh burdenClinical Interview
2020
Association of maternal depression and home adversities with infant hypothalamic-pituitary-adrenal (HPA) axis biomarkers in rural Pakistan
Hagaman AK, Baranov V, Chung E, LeMasters K, Andrabi N, Bates LM, Rahman A, Sikander S, Turner E, Maselko J. Association of maternal depression and home adversities with infant hypothalamic-pituitary-adrenal (HPA) axis biomarkers in rural Pakistan. Journal Of Affective Disorders 2020, 276: 592-599. PMID: 32871690, PMCID: PMC7792907, DOI: 10.1016/j.jad.2020.07.053.Peer-Reviewed Original ResearchConceptsHPA axis activityMaternal depressionSocio-economic statusYear postpartumDHEAS levelsAxis activityIntimate partner violenceInfant stress response systemsSignificant associationLow DHEAS levelsHPA axis dysregulationHPA axis hormonesOne-year-old infantsYears of ageConsistent significant associationsChildren's HPA-axis activityHigher socio-economic statusSignificant positive associationAxis dysregulationAxis hormonesAdrenal axisStress-related diseasesDHEA activityInfant cortisolDepression severity
2019
Cohort Profile: Perinatal depression and child socioemotional development ; the Bachpan cohort study from rural Pakistan
Sikander S, Ahmad I, Bates LM, Gallis J, Hagaman A, O’Donnell K, Turner EL, Zaidi A, Rahman A, Maselko J. Cohort Profile: Perinatal depression and child socioemotional development ; the Bachpan cohort study from rural Pakistan. BMJ Open 2019, 9: e025644. PMID: 31061029, PMCID: PMC6502044, DOI: 10.1136/bmjopen-2018-025644.Peer-Reviewed Original ResearchConceptsSocioemotional developmentDetrimental developmental outcomesChildren's socioemotional developmentMother-child dyadsPerinatal depressionEffect of depressionSocioemotional measuresChild developmentDevelopmental outcomesPsychosocial measuresPoor child developmentPregnancy birth cohortChild's ageSchool environmentCohort studyInflammatory biomarkersChronic courseEligible dyadsPregnant womenRisk factorsBaseline assessmentRepeated measuresDyadsDepressionChildrenThe relationship between responsive caregiving and child outcomes: evidence from direct observations of mother-child dyads in Pakistan
Scherer E, Hagaman A, Chung E, Rahman A, O’Donnell K, Maselko J. The relationship between responsive caregiving and child outcomes: evidence from direct observations of mother-child dyads in Pakistan. BMC Public Health 2019, 19: 252. PMID: 30819173, PMCID: PMC6396475, DOI: 10.1186/s12889-019-6571-1.Peer-Reviewed Original ResearchConceptsChildren's socioemotional developmentResponsive caregivingSocioemotional developmentChild developmentCaregiving behaviorChild outcomesMother-child interaction measuresMaternal depressionChildren's socioemotional outcomesMother-child dyadsChild development outcomesHierarchical linear regressionSocioemotional outcomesChild's signalsChild behaviorHome ObservationHOME scoresPhysical outcomesCaregivingLongitudinal studyLower scoresChild's lifeBook activitiesCross-sectional associationsBaseline sociodemographic factors