Variable Impact on Mortality of AIDS-Defining Events Diagnosed during Combination Antiretroviral Therapy: Not All AIDS-Defining Conditions Are Created Equal
Mocroft A, Sterne J, Egger M, May M, Grabar S, Furrer H, Sabin C, Fatkenheuer G, Justice A, Reiss P, d'Arminio Monforte A, Gill J, Hogg R, Bonnet F, Kitahata M, Staszewski S, Casabona J, Harris R, Saag M. Variable Impact on Mortality of AIDS-Defining Events Diagnosed during Combination Antiretroviral Therapy: Not All AIDS-Defining Conditions Are Created Equal. Clinical Infectious Diseases 2009, 48: 1138-1151. PMID: 19275498, PMCID: PMC3032444, DOI: 10.1086/597468.Peer-Reviewed Original ResearchConceptsCombination antiretroviral therapyMortality hazard ratioAntiretroviral therapyHazard ratioCombination antiretroviral therapy eraClinical end point trialsAntiretroviral therapy eraHIV transmission groupEnd point trialHIV RNA loadPneumocystis jiroveci pneumoniaProgressive multifocal leukoencephalopathyMortality of AIDSProportional hazards modelCommon ADEsMedian followTherapy eraJiroveci pneumoniaMultifocal leukoencephalopathyEsophageal candidiasisImmunodeficiency syndromeHodgkin's lymphomaRNA loadAntiretroviral drugsKaposi's sarcoma