2020
High concordance between chart review adjudication and electronic medical record data to identify prevalent and incident diabetes mellitus among persons with and without HIV
McGinnis KA, Justice AC, Bailin S, Wellons M, Freiberg M, Koethe JR. High concordance between chart review adjudication and electronic medical record data to identify prevalent and incident diabetes mellitus among persons with and without HIV. Pharmacoepidemiology And Drug Safety 2020, 29: 1432-1439. PMID: 33006179, PMCID: PMC7810212, DOI: 10.1002/pds.5111.Peer-Reviewed Original ResearchConceptsVeterans Health AdministrationElectronic medical recordsChart reviewVeterans Aging Cohort Study Biomarker CohortElectronic medical record dataPhysician chart reviewHIV-negative participantsIncident diabetes mellitusICD-9 codesMedical record dataIndication of diabetesPhysician adjudicationIncident diabetesDiabetes mellitusHIV infectionBiomarker cohortHIV statusDiabetes prevalenceMedical recordsMedication recordsLaboratory valuesEpidemiologic studiesDiabetes diagnosisDiagnostic criteriaDiabetesUsing longitudinal PSA values and machine learning for predicting progression of early stage prostate cancer in veterans.
Danciu I, Erwin S, Agasthya G, Janet T, McMahon B, Tourassi G, Justice A. Using longitudinal PSA values and machine learning for predicting progression of early stage prostate cancer in veterans. Journal Of Clinical Oncology 2020, 38: e17554-e17554. DOI: 10.1200/jco.2020.38.15_suppl.e17554.Peer-Reviewed Original ResearchDisease progressionClinical data warehouseLast PSAPSA valuesEarly-stage prostate cancerSEER summary stageTime of diagnosisAppropriate treatment planProstate cancer patientsStage prostate cancerHealth record dataProstate cancer diagnosisEvidence-based approachClinical decision supportCancer RegistryRadium-223Cancer patientsGleason scoreSummary stageLaboratory valuesProstate cancerTreatment planOutcome predictionDiagnosisPSA
2019
Improved discrimination of mortality with Veterans Aging Cohort Study (VACS) Index 2.0 in HIV-positive individuals
Tate JP, Sterne JAC, Justice AC. Improved discrimination of mortality with Veterans Aging Cohort Study (VACS) Index 2.0 in HIV-positive individuals. AIDS 2019, Publish Ahead of Print: &na;. PMID: 30649058, PMCID: PMC6749990, DOI: 10.1097/qad.0000000000002140.Peer-Reviewed Original ResearchConceptsWhite blood countC-statisticBlood countVeterans Aging Cohort Study (VACS) IndexAntiretroviral Therapy Cohort CollaborationDiscrimination of mortalityVACS Index 2.0Antiretroviral therapy initiationCD4 cell countHIV-positive populationHarrell's C-statisticHIV-1 RNAHIV-positive individualsKaplan-Meier plotsCohort CollaborationNadir CD4VAC patientsAntiretroviral therapyCause mortalityCD8 ratioTherapy initiationViral suppressionGeneral healthExcess mortalityLaboratory values
2017
White Blood Count, Albumin, and BMI Enhance VACS Index Prognostic Model, but Nadir CD4 and CD8 Metrics Do Not
Tate J, Brown S, Gibert C, Goetz M, Marconi V, Oursler K, Rimland D, Rodriguez-Barradas M, Justice A. White Blood Count, Albumin, and BMI Enhance VACS Index Prognostic Model, but Nadir CD4 and CD8 Metrics Do Not. Open Forum Infectious Diseases 2017, 4: s210-s210. PMCID: PMC5631891, DOI: 10.1093/ofid/ofx163.415.Peer-Reviewed Original ResearchWhite blood countAbsolute neutrophil countBody mass indexNadir CD4VACS IndexBlood countC-statisticVeterans Aging Cohort Study (VACS) IndexCD4/CD8 ratioLong-term viral suppressionKaplan-Meier plotsAvailable clinical dataDeciles of riskART initiationCD8 ratioViral suppressionNeutrophil countMass indexVA careClinical managementDisease burdenClinical dataExternal cohortLaboratory valuesRisk score