2017
FIB‐4 stage of liver fibrosis predicts incident heart failure among HIV‐infected and uninfected patients
So‐Armah K, Lim JK, Re V, Tate JP, Chang C, Butt AA, Gibert CL, Rimland D, Marconi VC, Goetz MB, Rodriguez‐Barradas M, Budoff MJ, Tindle HA, Samet JH, Justice AC, Freiberg MS, Team F. FIB‐4 stage of liver fibrosis predicts incident heart failure among HIV‐infected and uninfected patients. Hepatology 2017, 66: 1286-1295. PMID: 28543215, PMCID: PMC5609079, DOI: 10.1002/hep.29285.Peer-Reviewed Original ResearchConceptsHuman immunodeficiency virusFibrosis/cirrhosisHIV/HCV statusAdvanced fibrosis/cirrhosisLiver fibrosisCHF eventsHCV statusFIB-4Hepatitis CAdvanced liver fibrosis/cirrhosisIncident CHFCongestive heart failure riskCardiovascular disease risk factorsVeterans Aging Cohort StudyProportional hazards regression modelsLiver fibrosis/cirrhosisIncident CHF eventsRisk of CHFFibrosis-4 indexIncident heart failureDisease risk factorsHeart failure riskAging Cohort StudyCardiovascular disease riskPrevalent cardiovascular diseaseRisk of Acute Liver Injury After Statin Initiation by Human Immunodeficiency Virus and Chronic Hepatitis C Virus Infection Status
Byrne DD, Tate JP, Forde KA, Lim JK, Goetz MB, Rimland D, Rodriguez-Barradas MC, Butt AA, Gibert CL, Brown ST, Bedimo R, Freiberg MS, Justice AC, Kostman JR, Roy JA, Re V. Risk of Acute Liver Injury After Statin Initiation by Human Immunodeficiency Virus and Chronic Hepatitis C Virus Infection Status. Clinical Infectious Diseases 2017, 65: 1542-1550. PMID: 29020184, PMCID: PMC5850026, DOI: 10.1093/cid/cix564.Peer-Reviewed Original ResearchConceptsSevere acute liver injuryAcute liver injuryHuman immunodeficiency virusStatin initiatorsLower riskHCV statusCohort studyHazard ratioStatin nonusersLiver injuryUninfected personsImmunodeficiency virusChronic hepatitis C virus (HCV) infectionHepatitis C virus (HCV) infection statusHIV/HCV-coinfected patientsPropensity score-adjusted hazard ratiosHIV/HCV statusHepatitis C virus infectionVeterans Aging Cohort StudyC virus infectionAging Cohort StudyConfidence intervalsVirus infection statusDevelopment of liverAminotransferase elevation
2016
Hepatic Safety of Buprenorphine in HIV-Infected and Uninfected Patients With Opioid Use Disorder: The Role of HCV-Infection
Tetrault JM, Tate JP, Edelman EJ, Gordon AJ, Re V, Lim JK, Rimland D, Goulet J, Crystal S, Gaither JR, Gibert CL, Rodriguez-Barradas MC, Fiellin LE, Bryant K, Justice AC, Fiellin DA. Hepatic Safety of Buprenorphine in HIV-Infected and Uninfected Patients With Opioid Use Disorder: The Role of HCV-Infection. Journal Of Substance Use And Addiction Treatment 2016, 68: 62-67. PMID: 27431048, PMCID: PMC4976086, DOI: 10.1016/j.jsat.2016.06.002.Peer-Reviewed Original ResearchConceptsLiver enzyme elevationAlcohol use disorderUninfected patientsHepatotoxic medicationsHCV infectionUse disordersComposite endpointLiver injuryHIV/HCV co-infected patientsHCV co-infected patientsHIV/HCV statusPre-existing liver injuryCo-infected patientsCohort of HIVHepatitis C infectionHIV/HCVOpioid use disorderRisk of hepatotoxicityHCV statusHepatic safetyMedian ALTC infectionChart reviewEnzyme elevationHIV infection