2021
Developmental outcomes in children exposed to Zika virus in utero from a Brazilian urban slum cohort study
Ticona J, Nery N, Ladines-Lim JB, Gambrah C, Sacramento G, de Paula Freitas B, Bouzon J, Oliveira-Filho J, Borja A, Adhikarla H, Montoya M, Chin A, Wunder EA, Ballalai V, Vieira C, Belfort R, Almeida A, Reis MG, Harris E, Ko AI, Costa F. Developmental outcomes in children exposed to Zika virus in utero from a Brazilian urban slum cohort study. PLOS Neglected Tropical Diseases 2021, 15: e0009162. PMID: 33544730, PMCID: PMC7891708, DOI: 10.1371/journal.pntd.0009162.Peer-Reviewed Original ResearchConceptsPopulation attributable fractionZIKV exposureMonths of ageMild cognitive delayZika virus exposureZIKV-exposed childrenPopulation-based cohortCognitive delayDevelopmental alterationsMonoclonal antibody blockadeMonths of lifeGross birth defectsAppropriate control groupsProspective serosurveyCohort studyNeurodevelopmental outcomesAntibody blockadeNeurodevelopmental evaluationVirus exposureAttributable fractionBehavioral abnormalitiesControl groupRest of womenZika virusCohort
2017
Adverse birth outcomes associated with Zika virus exposure during pregnancy in São José do Rio Preto, Brazil
Nogueira ML, Júnior N, Estofolete CF, Terzian A, Guimarães GF, Zini N, da Silva R, Silva G, Franco L, Rahal P, Bittar C, Carneiro B, Vasconcelos PFC, Henriques D, Barbosa DMU, Rombola P, de Grande L, Reis A, Palomares SA, Catelan M, Cruz LEAA, Necchi SH, Mendonça RCV, dos Santos I, Caron S, Costa F, Bozza FA, de Souza A, de Mattos C, de Mattos LC, Vasilakis N, Oliani AH, Oliani D, Ko A. Adverse birth outcomes associated with Zika virus exposure during pregnancy in São José do Rio Preto, Brazil. Clinical Microbiology And Infection 2017, 24: 646-652. PMID: 29133154, DOI: 10.1016/j.cmi.2017.11.004.Peer-Reviewed Original ResearchConceptsAdverse outcomesZIKV infectionPregnant womenZika virusNewborn outcomesCongenital Zika infectionSame adverse outcomesZika virus exposureAdverse birth outcomesBroad clinical spectrumEmergence of ZIKVCases of microcephalyDengue-endemic areasPublic health authoritiesBirth outcomesClinical outcomesClinical presentationThird trimesterSubependymal cystsClinical spectrumZIKV RNAReverse transcription-PCRVirus exposureZika infectionEpidemiologic data