2024
Human antibodies in Mexico and Brazil neutralizing tick-borne flaviviruses
Cervantes Rincón T, Kapoor T, Keeffe J, Simonelli L, Hoffmann H, Agudelo M, Jurado A, Peace A, Lee Y, Gazumyan A, Guidetti F, Cantergiani J, Cena B, Bianchini F, Tamagnini E, Moro S, Svoboda P, Costa F, Reis M, Ko A, Fallon B, Avila-Rios S, Reyes-Téran G, Rice C, Nussenzweig M, Bjorkman P, Ruzek D, Varani L, MacDonald M, Robbiani D. Human antibodies in Mexico and Brazil neutralizing tick-borne flaviviruses. Cell Reports 2024, 43: 114298. PMID: 38819991, DOI: 10.1016/j.celrep.2024.114298.Peer-Reviewed Original ResearchPowassan virusEnvelope domain IIIYellow fever virusZika virusFever virusSerological neutralizing activityTemperate regionsDengue virusTicksTropical areasInfect humansLineage IMosquito-borne flavivirusNeutralizing activityHuman antibodiesVirusNeurological illnessBrazilFlavivirusesP002P003Human diseases
2019
Impact of preexisting dengue immunity on Zika virus emergence in a dengue endemic region
Rodriguez-Barraquer I, Costa F, Nascimento EJM, Nery N, Castanha PMS, Sacramento GA, Cruz J, Carvalho M, De Olivera D, Hagan JE, Adhikarla H, Wunder EA, Coêlho DF, Azar SR, Rossi SL, Vasilakis N, Weaver SC, Ribeiro GS, Balmaseda A, Harris E, Nogueira ML, Reis MG, Marques ETA, Cummings DAT, Ko AI. Impact of preexisting dengue immunity on Zika virus emergence in a dengue endemic region. Science 2019, 363: 607-610. PMID: 30733412, PMCID: PMC8221194, DOI: 10.1126/science.aav6618.Peer-Reviewed Original ResearchConceptsZika virusZIKV NS1 antigenAttack rateZika virus emergenceHigh antibody titersDengue-endemic regionsZIKV immunityClinical outcomesDengue immunityZIKV infectionAntibody titersNS1 antigenRisk factorsEndemic regionsDengue virusImmunityVirusRiskVirus emergenceFuture transmissionCohortSymptomsInfectionAntigenTiters