CCL9 Is Secreted by the Follicle-Associated Epithelium and Recruits Dome Region Peyer’s Patch CD11b+ Dendritic Cells
Zhao X, Sato A, Dela Cruz CS, Linehan M, Luegering A, Kucharzik T, Shirakawa AK, Marquez G, Farber JM, Williams I, Iwasaki A. CCL9 Is Secreted by the Follicle-Associated Epithelium and Recruits Dome Region Peyer’s Patch CD11b+ Dendritic Cells. The Journal Of Immunology 2003, 171: 2797-2803. PMID: 12960300, DOI: 10.4049/jimmunol.171.6.2797.Peer-Reviewed Original ResearchConceptsFollicle-associated epitheliumCCR6-deficient miceSubepithelial dome regionDendritic cellsPeyer's patchesMouse Peyer's patchesCCR6-/- miceDC recruitmentChemokine CCL20DC numbersAb neutralizationCCL9Villus epitheliumCCL20RT-PCRChemotaxis assaysProtein levelsMiceEpitheliumCCR6Vivo distributionImmunofluorescence analysisChemokinesSignificant reductionPutative receptor