2022
A new lineage of Galapagos giant tortoises identified from museum samples
Jensen E, Quinzin M, Miller J, Russello M, Garrick R, Edwards D, Glaberman S, Chiari Y, Poulakakis N, Tapia W, Gibbs J, Caccone A. A new lineage of Galapagos giant tortoises identified from museum samples. Heredity 2022, 128: 261-270. PMID: 35217806, PMCID: PMC8987048, DOI: 10.1038/s41437-022-00510-8.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsDNA, MitochondrialEcuadorGenomeHaplotypesHumansMicrosatellite RepeatsMuseumsPhylogenyTurtlesConceptsGalapagos giant tortoisesMitochondrial control regionGiant tortoisesSingle nucleotide polymorphismsControl regionMuseum samplesGenome-wide single nucleotide polymorphismsDivergent mitochondrial lineagesSingle mitochondrial haplotypeContemporary populationsIconic radiationMitochondrial lineagesAdditional lineagesMitochondrial haplotypesNuclear markersSan CristóbalSecond lineageMicrosatellite lociNew lineagePinta IslandSame cladeEvolutionary processesLineagesGalapagos ArchipelagoEarly evolution
2019
The population genomics of multiple tsetse fly (Glossina fuscipes fuscipes) admixture zones in Uganda
Saarman NP, Opiro R, Hyseni C, Echodu R, Opiyo EA, Dion K, Johnson T, Aksoy S, Caccone A. The population genomics of multiple tsetse fly (Glossina fuscipes fuscipes) admixture zones in Uganda. Molecular Ecology 2019, 28: 66-85. PMID: 30471158, PMCID: PMC9642080, DOI: 10.1111/mec.14957.Peer-Reviewed Original ResearchConceptsAdmixture zonePopulation genomicsHybrid zoneMitochondrial cytochrome oxidase IGenome-wide admixtureProcess of speciationCytochrome oxidase IPatterns of divergenceMaternal inheritance patternDivergent lineagesReproductive barriersSecondary contactOxidase IEvolutionary biologyApproximate Bayesian computationGenetic lineagesParental typesGenetic markersInheritance patternGenomicsLineagesMultiple generationsBayesian computationSpeciationRiver network
2017
Genetic diversity and population structure of the tsetse fly Glossina fuscipes fuscipes (Diptera: Glossinidae) in Northern Uganda: Implications for vector control
Opiro R, Saarman NP, Echodu R, Opiyo EA, Dion K, Halyard A, Dunn AW, Aksoy S, Caccone A. Genetic diversity and population structure of the tsetse fly Glossina fuscipes fuscipes (Diptera: Glossinidae) in Northern Uganda: Implications for vector control. PLOS Neglected Tropical Diseases 2017, 11: e0005485. PMID: 28453513, PMCID: PMC5425221, DOI: 10.1371/journal.pntd.0005485.Peer-Reviewed Original ResearchConceptsAnimal African trypanosomiasisGenetic clustersEffective population size estimatesLake KyogaRecent population bottleneckMitochondrial DNA markersDistinct genetic clustersPolymorphic microsatellite lociNile drainagePopulation size estimatesGenetic structurePopulation bottlenecksMain haplogroupsGenetic diversityMicrosatellite lociGenetic assignmentDNA markersPopulation structureMtDNA analysisGenetic admixtureSampling sitesGenetic unitsMost populationsTrypanosoma parasitesHuman African trypanosomiasis
2016
Evidence of temporal stability in allelic and mitochondrial haplotype diversity in populations of Glossina fuscipes fuscipes (Diptera: Glossinidae) in northern Uganda
Opiro R, Saarman NP, Echodu R, Opiyo EA, Dion K, Halyard A, Aksoy S, Caccone A. Evidence of temporal stability in allelic and mitochondrial haplotype diversity in populations of Glossina fuscipes fuscipes (Diptera: Glossinidae) in northern Uganda. Parasites & Vectors 2016, 9: 258. PMID: 27141947, PMCID: PMC4855780, DOI: 10.1186/s13071-016-1522-5.Peer-Reviewed Original Research
2013
Wolbachia association with the tsetse fly, Glossina fuscipes fuscipes, reveals high levels of genetic diversity and complex evolutionary dynamics
Symula RE, Alam U, Brelsfoard C, Wu Y, Echodu R, Okedi LM, Aksoy S, Caccone A. Wolbachia association with the tsetse fly, Glossina fuscipes fuscipes, reveals high levels of genetic diversity and complex evolutionary dynamics. BMC Ecology And Evolution 2013, 13: 31. PMID: 23384159, PMCID: PMC3574847, DOI: 10.1186/1471-2148-13-31.Peer-Reviewed Original ResearchConceptsMtDNA haplotypesDifferent WolbachiaGenetic diversityHost haplotypesSequence diversityMultiple WolbachiaArthropod host reproductionPopulation genetic differentiationComplex evolutionary dynamicsMitochondrial DNA haplotypesAssociation of WolbachiaLow reproductive outputHost population geneticsHost genetic diversityTsetse fliesMulti-locus sequence typingMost WolbachiaHost genetic compositionGenetic differentiationWolbachia evolutionWolbachia associationsHost reproductionDNA haplotypesMtDNA groupsΑ-proteobacteria
2011
Lineage Identification and Genealogical Relationships Among Captive Galápagos Tortoises
Benavides E, Russello M, Boyer D, Wiese R, Kajdacsi B, Marquez L, Garrick R, Caccone A. Lineage Identification and Genealogical Relationships Among Captive Galápagos Tortoises. Zoo Biology 2011, 31: 107-120. PMID: 21674601, DOI: 10.1002/zoo.20397.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsAnimals, WildAnimals, ZooGenetic MarkersGenomicsHaplotypesMicrosatellite RepeatsTurtlesConceptsGenealogical relationshipsGalápagos tortoisesEx situ conservation programsMicrosatellite genotypic dataSan Diego ZooGalápagos giant tortoisesWild-born individualsSitu conservation programsLevels of relatednessDetailed management recommendationsSanta Cruz IslandEvolutionary lineagesAssignment testsGenetic toolsSpecies designationRelated foundersGiant tortoisesGenotypic dataUnknown ancestryHaplotypic dataPedigree relationshipsDifferent speciesLineage identificationIsabela IslandConservation programsTemporal stability of Glossina fuscipes fuscipes populations in Uganda
Echodu R, Beadell JS, Okedi LM, Hyseni C, Aksoy S, Caccone A. Temporal stability of Glossina fuscipes fuscipes populations in Uganda. Parasites & Vectors 2011, 4: 19. PMID: 21320301, PMCID: PMC3045980, DOI: 10.1186/1756-3305-4-19.Peer-Reviewed Original ResearchConceptsEffective population size estimatesMitochondrial haplotype frequenciesEstimates of differentiationZone of contactJost's DESTPopulation size estimatesMitochondrial lociMating compatibilityMicrosatellite frequenciesMicrosatellite lociRiverine speciesPopulation dynamicsGenetic changesObserved seasonal fluctuationsHuman African trypanosomiasisMajor vectorSingle populationG. fuscipesTsetse fliesFuscipesAllele frequenciesHaplotype frequenciesLociSeasonal fluctuationsTime of samplingPhylogeography and Taxonomy of Trypanosoma brucei
Balmer O, Beadell J, Gibson W, Caccone A. Phylogeography and Taxonomy of Trypanosoma brucei. PLOS Neglected Tropical Diseases 2011, 5: e961. PMID: 21347445, PMCID: PMC3035665, DOI: 10.1371/journal.pntd.0000961.Peer-Reviewed Original Research
2010
Genetic Differentiation between Marine Iguanas from Different Breeding Sites on the Island of Santa Fé (Galápagos Archipelago)
Lanterbecq D, Glaberman S, Vitousek M, Steinfartz S, Benavides E, Wikelski M, Caccone A. Genetic Differentiation between Marine Iguanas from Different Breeding Sites on the Island of Santa Fé (Galápagos Archipelago). Journal Of Heredity 2010, 101: 663-675. PMID: 20538757, DOI: 10.1093/jhered/esq067.Peer-Reviewed Original ResearchConceptsMarine iguanasGenetic diversitySex-biased dispersalMitochondrial control regionMitochondrial DNA markersGalápagos marine iguanasSanta FéDifferent breeding sitesSouthern sitesGenetic differentiationEvolutionary signalGenetic structureMicrosatellite lociDNA markersControl regionGenetic variationGenetic patternsBreeding sitesLittle differentiationBase pairsNeighboring islandsIguanasDiversitySampling sitesDifferentiationDNA from the Past Informs Ex Situ Conservation for the Future: An “Extinct” Species of Galápagos Tortoise Identified in Captivity
Russello MA, Poulakakis N, Gibbs JP, Tapia W, Benavides E, Powell JR, Caccone A. DNA from the Past Informs Ex Situ Conservation for the Future: An “Extinct” Species of Galápagos Tortoise Identified in Captivity. PLOS ONE 2010, 5: e8683. PMID: 20084268, PMCID: PMC2800188, DOI: 10.1371/journal.pone.0008683.Peer-Reviewed Original ResearchConceptsExtinct speciesCaptive individualsGenotypic dataExtant speciesGalápagos tortoisesNative rangeTortoise speciesMitochondrial DNA control region haplotypesHistorical DNA analysisMicrosatellite genotypic dataControl region haplotypesMitochondrial DNA haplotypesEx situ conservationSpecies recovery effortsConservation-related researchIslands of IsabelaCryptic diversityBayesian assignmentDNA haplotypesSitu conservationFloreana IslandConservation statusBreeding effortsMicrosatellite genotypesMuseum specimens
2004
Variation in an intron sequence of the voltage‐gated sodium channel gene correlates with genetic differentiation between Anopheles gambiae s.s. molecular forms
Gentile G, Santolamazza F, Fanello C, Petrarca V, Caccone A, Della Torre A. Variation in an intron sequence of the voltage‐gated sodium channel gene correlates with genetic differentiation between Anopheles gambiae s.s. molecular forms. Insect Molecular Biology 2004, 13: 371-377. PMID: 15271209, DOI: 10.1111/j.0962-1075.2004.00494.x.Peer-Reviewed Original ResearchConceptsVoltage-gated sodium channel geneSodium channel geneGenetic differentiationGenetic variationChannel genesPossible selective sweepMajor haplotypesSingle mutational stepAnopheles gambiae MRDNA sitesGene flowSelective sweepsMutational stepsTaxonomic statusIntron sequencesGambiae MMolecular formsIntron ISingle localityIntronic regionsAnopheles gambiae s.Additional haplotypesGambiae s.HaplotypesGenesGenetic evaluation of a proposed introduction: the case of the greater prairie chicken and the extinct heath hen
Palkovacs E, Oppenheimer A, Gladyshev E, Toepfer J, Amato G, Chase T, Caccone A. Genetic evaluation of a proposed introduction: the case of the greater prairie chicken and the extinct heath hen. Molecular Ecology 2004, 13: 1759-1769. PMID: 15189201, DOI: 10.1111/j.1365-294x.2004.02181.x.Peer-Reviewed Original ResearchConceptsGreater prairie-chickensPrairie-ChickensMitochondrial control region sequencesDivergent mitochondrial lineagesPrairie grouseControl region sequencesDifferent habitat typesEcological exchangeabilityMitochondrial lineagesExtant populationsPopulation bottlenecksMtDNA haplotypesHabitat typesExtirpated populationsPopulation introductionsGrouse speciesGenetic analysisRegion sequencesGeographical isolationHuman disturbanceGrouse populationsEcosystem restorationEcosystem restoration projectsHen populationRestoration projectsGiant tortoises are not so slow: Rapid diversification and biogeographic consensus in the Galápagos
Beheregaray L, Gibbs J, Havill N, Fritts T, Powell J, Caccone A. Giant tortoises are not so slow: Rapid diversification and biogeographic consensus in the Galápagos. Proceedings Of The National Academy Of Sciences Of The United States Of America 2004, 101: 6514-6519. PMID: 15084743, PMCID: PMC404076, DOI: 10.1073/pnas.0400393101.Peer-Reviewed Original ResearchConceptsGiant Galápagos tortoisesGalápagos tortoisesGreat natural laboratoryGenetic variationDivergent monophyletic cladesHistory of diversificationIsolated oceanic archipelagoPatterns of colonizationBiogeographic predictionsEvolutionary diversificationGene flowEndemic haplotypesExtant populationsLimited dispersalOceanic archipelagosBiogeographic patternsEvolutionary eventsBiological diversificationMonophyletic cladeMtDNA sequencesRapid diversificationGenetic interchangeRange expansionOlder islandsGiant tortoises
2003
Genes Record a Prehistoric Volcano Eruption in the Galápagos
Beheregaray L, Ciofi C, Geist D, Gibbs J, Caccone A, Powell J. Genes Record a Prehistoric Volcano Eruption in the Galápagos. Science 2003, 302: 75-75. PMID: 14526072, DOI: 10.1126/science.1087486.Peer-Reviewed Original Research
2002
PHYLOGEOGRAPHY AND HISTORY OF GIANT GALAPAGOS TORTOISES
Caccone A, Gentile G, Gibbs JP, Fritts T, Snell HL, Betts J, Powell JR. PHYLOGEOGRAPHY AND HISTORY OF GIANT GALAPAGOS TORTOISES. Evolution 2002, 56: 2052-2066. PMID: 12449492, DOI: 10.1111/j.0014-3820.2002.tb00131.x.Peer-Reviewed Original ResearchConceptsMultiple colonizationsMaternal lineagesMitochondrial DNA sequence dataClear genetic differentiationDNA sequence dataSanta Cruz IslandBiological treasureComplex phylogeographyGenetic differentiationExtant islandsPinzón IslandMolecular clockDeep nodesExtant taxaSequence dataVolcan WolfYounger islandsInsular environmentsHuman transportPhylogeographyTortoise populationsTaxaIsabela IslandDistinct populationsLineages