2020
Evolution of kdr haplotypes in worldwide populations of Aedes aegypti: Independent origins of the F1534C kdr mutation
Cosme LV, Gloria-Soria A, Caccone A, Powell JR, Martins AJ. Evolution of kdr haplotypes in worldwide populations of Aedes aegypti: Independent origins of the F1534C kdr mutation. PLOS Neglected Tropical Diseases 2020, 14: e0008219. PMID: 32298261, PMCID: PMC7188295, DOI: 10.1371/journal.pntd.0008219.Peer-Reviewed Original Research
2018
Uncovering Genomic Regions Associated with Trypanosoma Infections in Wild Populations of the Tsetse Fly Glossina fuscipes
Gloria-Soria A, Dunn WA, Yu X, Vigneron A, Lee KY, Li M, Weiss BL, Zhao H, Aksoy S, Caccone A. Uncovering Genomic Regions Associated with Trypanosoma Infections in Wild Populations of the Tsetse Fly Glossina fuscipes. G3: Genes, Genomes, Genetics 2018, 8: 887-897. PMID: 29343494, PMCID: PMC5844309, DOI: 10.1534/g3.117.300493.Peer-Reviewed Original ResearchConceptsGenomic resourcesRelated speciesCandidate genesNonmodel organismsTranscript librariesFunctional genomicsTranscriptome assemblyFunctional annotationWild populationsPhysiological traitsGenomic regionsDNA regulationMost speciesRNAseq experimentsGenetic basisLaboratory coloniesGenesFunctional studiesPolymorphic sitesSpeciesTrypanosome infection statusGenomeNew assemblyTrypanosoma infectionFlies
2016
Patterns of Genome-Wide Variation in Glossina fuscipes fuscipes Tsetse Flies from Uganda
Gloria-Soria A, Dunn WA, Telleria EL, Evans BR, Okedi L, Echodu R, Warren WC, Montague MJ, Aksoy S, Caccone A. Patterns of Genome-Wide Variation in Glossina fuscipes fuscipes Tsetse Flies from Uganda. G3: Genes, Genomes, Genetics 2016, 6: 1573-1584. PMID: 27172181, PMCID: PMC4889654, DOI: 10.1534/g3.116.027235.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsChromosome MappingDNA, MitochondrialGene-Environment InteractionGenes, InsectGenetic LinkageGenetic VariationGenetics, PopulationGenome-Wide Association StudyGenome, InsectGenomicsGenotypeGeographyHigh-Throughput Nucleotide SequencingLinkage DisequilibriumMicrosatellite RepeatsPolymorphism, Single NucleotideSelection, GeneticTsetse FliesUgandaConceptsSingle nucleotide polymorphismsLinkage disequilibriumExtent of LDLocal environmental adaptationGenome-wide variationDetection of lociOverall linkage disequilibriumInsect vectorsDifferent environmental conditionsWhole-genome sequencingPopulation genomicsStrong selectionAssociation analysisEnvironmental adaptationGenomic patternsPopulation dynamicsSignificant genetic associationUninfected fliesDisease transmissionSequence technologyAssociation studiesEnvironmental conditionsTsetse fliesHuman African trypanosomiasisRelevant phenotypes
2013
HUMAN IMPACTS HAVE SHAPED HISTORICAL AND RECENT EVOLUTION IN AEDES AEGYPTI, THE DENGUE AND YELLOW FEVER MOSQUITO
Brown JE, Evans BR, Zheng W, Obas V, Barrera‐Martinez L, Egizi A, Zhao H, Caccone A, Powell JR. HUMAN IMPACTS HAVE SHAPED HISTORICAL AND RECENT EVOLUTION IN AEDES AEGYPTI, THE DENGUE AND YELLOW FEVER MOSQUITO. Evolution 2013, 68: 514-525. PMID: 24111703, PMCID: PMC3946797, DOI: 10.1111/evo.12281.Peer-Reviewed Original ResearchConceptsYellow fever mosquitoSingle nucleotide polymorphism (SNP) markersHuman trade routesPatterns of domesticationArthropod disease vectorsDomestic formsNuclear genesEcological overlapEvolutionary historyDomestic AePolymorphism markersNovel nichesDNA sequencesGenetic dataEvolutionary processesDisease vectorsGenetic studiesSuch speciesLater invasionDNA sequencingNew WorldSpeciesAnthropogenic impactsHuman impactAnthropogenic forces
2008
The molecular evolution of four anti-malarial immune genes in the Anopheles gambiae species complex
Parmakelis A, Slotman MA, Marshall JC, Awono-Ambene PH, Antonio-Nkondjio C, Simard F, Caccone A, Powell JR. The molecular evolution of four anti-malarial immune genes in the Anopheles gambiae species complex. BMC Ecology And Evolution 2008, 8: 79. PMID: 18325105, PMCID: PMC2288592, DOI: 10.1186/1471-2148-8-79.Peer-Reviewed Original ResearchConceptsInsect innate immune systemAnopheles gambiae speciesLevel of polymorphismAnopheles gambiae complexSpecific adaptive responsesAncestral polymorphismPhylogenetic frameworkMolecular evolutionSuch genesGambiae speciesPositive selectionImmunity genesSelection pressureCandidate genesImmune genesMosquito's abilityGambiae complexStudied genesGenesInnate immune systemAdaptive responseMalaria parasitesPlasmodium parasitesEase of manipulationSpecies
2006
Co‐occurrence of East and West African kdr mutations suggests high levels of resistance to pyrethroid insecticides in Anopheles gambiae from Libreville, Gabon
Pinto J, Lynd A, Elissa N, Donnelly M, Costa C, Gentile G, Caccone A, DO Rosário V. Co‐occurrence of East and West African kdr mutations suggests high levels of resistance to pyrethroid insecticides in Anopheles gambiae from Libreville, Gabon. Medical And Veterinary Entomology 2006, 20: 27-32. PMID: 16608487, DOI: 10.1111/j.1365-2915.2006.00611.x.Peer-Reviewed Original Research
2001
Attempts to molecularly distinguish cryptic taxa in Anopheles gambiae s.s.
Gentile G, Slotman M, Ketmaier V, Powell J, Caccone A. Attempts to molecularly distinguish cryptic taxa in Anopheles gambiae s.s. Insect Molecular Biology 2001, 10: 25-32. PMID: 11240634, DOI: 10.1046/j.1365-2583.2001.00237.x.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsAnophelesBase SequenceDNA, ComplementaryDNA, MitochondrialDNA, RibosomalGenes, InsectMolecular Sequence DataConceptsRibosomal DNAChromosomal formsRDNA typesIntergenic spacerRestricted gene flowSingle taxonomic unitRDNA intergenic spacerCryptic taxaMitochondrial genomeGene flowReproductive isolationGenetic discontinuityPolytene chromosomesTaxonomic unitsAnalysis of inversionsITS typesNucleotide sitesAnopheles gambiaeNew taxonAnopheles gambiae s.Type IGenomeTaxaGambiae s.São Tomé
1996
A molecular phylogeny for the Drosophila melanogaster subgroup and the problem of polymorphism data.
Caccone A, Moriyama E, Gleason J, Nigro L, Powell J. A molecular phylogeny for the Drosophila melanogaster subgroup and the problem of polymorphism data. Molecular Biology And Evolution 1996, 13: 1224-1232. PMID: 8896375, DOI: 10.1093/oxfordjournals.molbev.a025688.Peer-Reviewed Original ResearchConceptsDNA-DNA hybridization dataDNA sequence dataSequence dataD. sechelliaMelanogaster subgroupD. mauritianaHybridization dataNuclear DNA sequence dataPrevious DNA-DNA hybridization dataNew DNA sequence dataSerendipity alpha geneDrosophila melanogaster subgroupITS of rDNAD. simulansIsland speciesMolecular phylogenyDrosophila melanogasterPhylogenetic relationshipsSister statusIntraspecific polymorphismPhylogenetic standpointRelated speciesPhylogenetic inferenceMost speciesParallel evolution