2014
Comparative Genomics Reveals Multiple Genetic Backgrounds of Human Pathogenicity in the Trypanosoma brucei Complex
Sistrom M, Evans B, Bjornson R, Gibson W, Balmer O, Mäser P, Aksoy S, Caccone A. Comparative Genomics Reveals Multiple Genetic Backgrounds of Human Pathogenicity in the Trypanosoma brucei Complex. Genome Biology And Evolution 2014, 6: 2811-2819. PMID: 25287146, PMCID: PMC4224348, DOI: 10.1093/gbe/evu222.Peer-Reviewed Original ResearchConceptsT. brucei complexGenomic variationLife historyVariable life historiesAverage linkage disequilibriumTrypanosoma brucei complexGenome-wide studiesMeiotic reciprocal recombinationWhole genome sequencesMultiple genetic backgroundsHuman pathogenicityNumber of subspeciesHuman-infective parasiteNuclear genomeComparative genomicsChromosome sizeEukaryotic parasitesGenomic regionsHuman African trypanosomiasisRegulatory genesTaxonomic designationsDiverse hostsSingle nucleotide polymorphismsGenetic variationReciprocal recombination
1990
EVOLUTIONARY IMPLICATIONS OF DNA DIVERGENCE IN THE DROSOPHILA OBSCURA GROUP
Goddard K, Caccone A, Powell J. EVOLUTIONARY IMPLICATIONS OF DNA DIVERGENCE IN THE DROSOPHILA OBSCURA GROUP. Evolution 1990, 44: 1656-1670. PMID: 28564311, DOI: 10.1111/j.1558-5646.1990.tb03854.x.Peer-Reviewed Original ResearchDrosophila obscura groupObscura groupOld World speciesWorld speciesDNA divergenceSingle-copy DNA divergencePartial reproductive isolationGroups of DrosophilaDNA-DNA hybridizationNew World speciesObscura subgroupMelanogaster subgroupAffinis subgroupNuclear genomeReproductive isolationChromosomal divergenceEvolutionary implicationsMonophyletic groupClassical systematicsRelated taxaMitochondrial DNASpeciesHybrid formationOld WorldGenomeExtreme rates and heterogeneity in insect DNA evolution
Caccone A, Powell J. Extreme rates and heterogeneity in insect DNA evolution. Journal Of Molecular Evolution 1990, 30: 273-280. PMID: 2109089, DOI: 10.1007/bf02099997.Peer-Reviewed Original ResearchConceptsSingle-copy DNA divergenceDNA-DNA hybridization studiesSingle-copy DNAInsect genomesGenome evolutionDNA divergenceNuclear genomeDNA evolutionEvolutionary changeChromosomal similaritiesInterspecific hybridsMost vertebratesMorphological similarityGenomeIntronsHybridization studiesInsectsMammalsBirdsDNAExtreme variationVertebratesTaxaExonsSimilarity