Marginal interaction test for detecting interactions between genetic marker sets and environment in genome-wide studies
Shen L, Amei A, Liu B, Xu G, Liu Y, Oh E, Zhou X, Wang Z. Marginal interaction test for detecting interactions between genetic marker sets and environment in genome-wide studies. G3: Genes, Genomes, Genetics 2024, jkae263. PMID: 39538414, DOI: 10.1093/g3journal/jkae263.Peer-Reviewed Original ResearchGene-environment interactionsStudies of complex diseasesMulti-Ethnic Study of AtherosclerosisComplex diseasesGenetic marker setsGenome-wide analysisGenome-wide studiesHuman complex diseasesGene-alcohol interactionsMulti-Ethnic StudyGenetic main effectsStudy of AtherosclerosisSignal transduction pathwaysAssociated with hypertensionBlood pressureSystolic blood pressureGenetic markersEnvironmental factorsAlcohol intakeGenetic variantsTransduction pathwaysSurvival pathwaysMarker setsPathway analysisRare variants