Exposure to per- and polyfluoroalkyl substances in early pregnancy and risk of cerebral palsy in children
Vilhelmsson A, Rylander L, Jöud A, Lindh C, Mattsson K, Liew Z, Guo P, Ritz B, Källén K, Thacher J. Exposure to per- and polyfluoroalkyl substances in early pregnancy and risk of cerebral palsy in children. The Science Of The Total Environment 2023, 899: 165622. PMID: 37474063, DOI: 10.1016/j.scitotenv.2023.165622.Peer-Reviewed Original ResearchConceptsOdds ratioPreterm infantsEarly pregnancyPerfluorononanoic acidPrenatal PFAS exposureMaternal serum concentrationsCerebral palsy casesConfidence intervalsCase-control studyRisk of CPEnvironmental risk factorsPositive associationContinuous variablesHigh PFASPalsy casesBirth RegistryPreterm controlsCerebral palsyLifestyle factorsPreterm casesUnexplained etiologyPrenatal exposureSerum concentrationsRisk factorsPerfluorooctane sulfonateAssociation Between Estimated Geocoded Residential Maternal Exposure to Lithium in Drinking Water and Risk for Autism Spectrum Disorder in Offspring in Denmark
Liew Z, Meng Q, Yan Q, Schullehner J, Hansen B, Kristiansen S, Voutchkova D, Olsen J, Ersbøll A, Ketzel M, Raaschou-Nielsen O, Ritz B. Association Between Estimated Geocoded Residential Maternal Exposure to Lithium in Drinking Water and Risk for Autism Spectrum Disorder in Offspring in Denmark. JAMA Pediatrics 2023, 177: 617-624. PMID: 37010840, PMCID: PMC10071398, DOI: 10.1001/jamapediatrics.2023.0346.Peer-Reviewed Original ResearchConceptsMaternal exposureOdds ratioStratified analysisNationwide population-based case-control studyPopulation-based case-control studyDanish Medical Birth RegistryDanish Psychiatric Central RegisterAutism spectrum disorderMedical Birth RegistryNovel environmental risk factorTenth Revision codesAdverse birth outcomesControl participantsMaternal prenatal exposureMaternal residential addressBirth yearCase-control studyPsychiatric Central RegisterMood-stabilizing effectsAir pollution exposureEnvironmental risk factorsInternational Statistical ClassificationWnt/β-catenin signalingStudy teamRelated Health Problems