2024
Maternal intake of paracetamol during pregnancy and biomarkers of male fecundity in young adult sons
Laursen T, Ramlau-Hansen C, Tøttenborg S, Liew Z, Toft G, Gaml-Sørensen A, Hougaard K, Bonde J, Ernst A. Maternal intake of paracetamol during pregnancy and biomarkers of male fecundity in young adult sons. Reproductive Toxicology 2024, 127: 108626. PMID: 38815769, DOI: 10.1016/j.reprotox.2024.108626.Peer-Reviewed Original ResearchIntake of paracetamolMaternal intakeHigher DNA fragmentation indexDanish National Birth CohortDNA fragmentation indexSemen characteristicsLong durationImpaired semen qualityConfidence intervalsImpaired semen characteristicsNational Birth CohortReproductive hormone levelsAssociated with biomarkersDuration of exposureYears of ageFetal programmingNo intakeImmotile spermatozoaSons of mothersFollow-upYoung adult menHormone levelsSemen qualityMale fecundityTrimester-specific
2023
Exposure to per- and polyfluoroalkyl substances in early pregnancy and risk of cerebral palsy in children
Vilhelmsson A, Rylander L, Jöud A, Lindh C, Mattsson K, Liew Z, Guo P, Ritz B, Källén K, Thacher J. Exposure to per- and polyfluoroalkyl substances in early pregnancy and risk of cerebral palsy in children. The Science Of The Total Environment 2023, 899: 165622. PMID: 37474063, DOI: 10.1016/j.scitotenv.2023.165622.Peer-Reviewed Original ResearchConceptsOdds ratioPreterm infantsEarly pregnancyPerfluorononanoic acidPrenatal PFAS exposureMaternal serum concentrationsCerebral palsy casesConfidence intervalsCase-control studyRisk of CPEnvironmental risk factorsPositive associationContinuous variablesHigh PFASPalsy casesBirth RegistryPreterm controlsCerebral palsyLifestyle factorsPreterm casesUnexplained etiologyPrenatal exposureSerum concentrationsRisk factorsPerfluorooctane sulfonateResidential proximity to unconventional oil and gas development and birth defects in Ohio
Gaughan C, Sorrentino K, Liew Z, Johnson N, Clark C, Soriano M, Plano J, Plata D, Saiers J, Deziel N. Residential proximity to unconventional oil and gas development and birth defects in Ohio. Environmental Research 2023, 229: 115937. PMID: 37076028, PMCID: PMC10198955, DOI: 10.1016/j.envres.2023.115937.Peer-Reviewed Original ResearchConceptsNeural tube defectsCertain birth defectsBirth defectsOdds ratioRegistry-based cohort studyTube defectsConfidence intervalsResidential proximityState birth recordsBirth defect typeState surveillance systemsMaternal residential proximityLimb reduction defectsCohort studyUnexposed mothersStructural birth defectsLive birthsInfant sexBirth recordsSpina bifidaReduction defectsFemale offspringDevelopmental toxicantsExposure metrics