1998
Administration of Methylprednisolone for 24 or 48 Hours or Tirilazad Mesylate for 48 Hours in the Treatment of Acute Spinal Cord Injury
BRACKEN M, SHEPARD M, HOLFORD T, LEO-SUMMERS L, ALDRICH E, FAZL M, FEHLINGS M, HERR D, HITCHON P, MARSHALL L, NOCKELS R, PASCALE V, PEROT P, PIEPMEIER J, SONNTAG V, WAGNER F, WILBERGER J, WINN H, YOUNG W. Administration of Methylprednisolone for 24 or 48 Hours or Tirilazad Mesylate for 48 Hours in the Treatment of Acute Spinal Cord Injury. Survey Of Anesthesiology 1998, 42: 197. DOI: 10.1097/00132586-199808000-00011.Peer-Reviewed Original ResearchAcute spinal cord injuryAdministration of methylprednisoloneSpinal cord injuryTirilazad mesylateCord injuryHoursMethylprednisoloneInjuryAdministrationMesylate
1997
Administration of Methylprednisolone for 24 or 48 Hours or Tirilazad Mesylate for 48 Hours in the Treatment of Acute Spinal Cord Injury: Results of the Third National Acute Spinal Cord Injury Randomized Controlled Trial
Bracken M, Shepard M, Holford T, Leo-Summers L, Aldrich E, Fazl M, Fehlings M, Herr D, Hitchon P, Marshall L, Nockels R, Pascale V, Perot P, Piepmeier J, Sonntag V, Wagner F, Wilberger J, Winn H, Young W. Administration of Methylprednisolone for 24 or 48 Hours or Tirilazad Mesylate for 48 Hours in the Treatment of Acute Spinal Cord Injury: Results of the Third National Acute Spinal Cord Injury Randomized Controlled Trial. JAMA 1997, 277: 1597-1604. DOI: 10.1001/jama.1997.03540440031029.Peer-Reviewed Original ResearchAcute spinal cord injurySpinal cord injuryNational Acute Spinal Cord Injury StudyFunctional Independence MeasureHours of injuryCord injuryTirilazad groupRegimen groupTirilazad mesylateMethylprednisolone infusionAcute Spinal Cord Injury StudySpinal Cord Injury StudySpinal cord injury centerEfficacy of methylprednisoloneImproved motor recoveryMotor recovery rateAdministration of methylprednisoloneMotor function changesSteroid therapyMethylprednisolone groupSevere sepsisMotor recoveryControlled TrialsInitial presentationIntravenous bolus