2020
Risk factors for recurrent tuberculosis after successful treatment in a high burden setting: a cohort study
Cudahy PGT, Wilson D, Cohen T. Risk factors for recurrent tuberculosis after successful treatment in a high burden setting: a cohort study. BMC Infectious Diseases 2020, 20: 789. PMID: 33097000, PMCID: PMC7585300, DOI: 10.1186/s12879-020-05515-4.Peer-Reviewed Original ResearchConceptsM. tuberculosis infectionRecurrent tuberculosisSuccessful treatmentTuberculosis recurrenceHazard ratioSmear gradeTuberculosis infectionRisk factorsSmear-positive pulmonary tuberculosisCox proportional hazards modelSputum smear gradeRepetitive unit-variable number tandem repeat (MIRU-VNTR) typingHigh-burden settingsRisk of recurrenceProportional hazards modelSuccessful treatment completionRecurrent diseaseCohort studyPulmonary tuberculosisBurden settingsClinical presentationRecurrent episodesInitial episodeNumber tandem repeat typingTreatment completion
2018
Towards better prediction of Mycobacterium tuberculosis lineages from MIRU-VNTR data
Thain N, Le C, Crossa A, Ahuja SD, Meissner JS, Mathema B, Kreiswirth B, Kurepina N, Cohen T, Chindelevitch L. Towards better prediction of Mycobacterium tuberculosis lineages from MIRU-VNTR data. Infection Genetics And Evolution 2018, 72: 59-66. PMID: 29960078, PMCID: PMC6708508, DOI: 10.1016/j.meegid.2018.06.029.Peer-Reviewed Original ResearchInternal migration and transmission dynamics of tuberculosis in Shanghai, China: an epidemiological, spatial, genomic analysis
Yang C, Lu L, Warren JL, Wu J, Jiang Q, Zuo T, Gan M, Liu M, Liu Q, DeRiemer K, Hong J, Shen X, Colijn C, Guo X, Gao Q, Cohen T. Internal migration and transmission dynamics of tuberculosis in Shanghai, China: an epidemiological, spatial, genomic analysis. The Lancet Infectious Diseases 2018, 18: 788-795. PMID: 29681517, PMCID: PMC6035060, DOI: 10.1016/s1473-3099(18)30218-4.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedAged, 80 and overChinaDisease Transmission, InfectiousFemaleGenotypeHumansMaleMiddle AgedMinisatellite RepeatsMolecular EpidemiologyMycobacterium tuberculosisPolymorphism, Single NucleotideRural PopulationSpatial AnalysisTransients and MigrantsTuberculosisUrban PopulationWhole Genome SequencingConceptsM tuberculosisEpidemiological dataSingle nucleotide polymorphismsCulture-positive Mycobacterium tuberculosis isolatesCulture-positive tuberculosisPopulation-based studyMycobacterium tuberculosis isolatesTransmission dynamicsTime of infectionDynamics of tuberculosisTuberculosis controlUS National InstitutesTuberculosis isolatesMore effective interventionsProximity of residenceRecent transmissionPatient's homeTuberculosisLocal transmission dynamicsEffective interventionsLocal transmissionLocal incidenceNational InstituteVNTR patternsWhole-genome sequencing
2016
ClassTR: Classifying Within-Host Heterogeneity Based on Tandem Repeats with Application to Mycobacterium tuberculosis Infections
Chindelevitch L, Colijn C, Moodley P, Wilson D, Cohen T. ClassTR: Classifying Within-Host Heterogeneity Based on Tandem Repeats with Application to Mycobacterium tuberculosis Infections. PLOS Computational Biology 2016, 12: e1004475. PMID: 26829497, PMCID: PMC4734664, DOI: 10.1371/journal.pcbi.1004475.Peer-Reviewed Original Research