2022
Spatially targeted digital chest radiography to reduce tuberculosis in high-burden settings: A study of adaptive decision making
de Villiers AK, Dye C, Yaesoubi R, Cohen T, Marx FM. Spatially targeted digital chest radiography to reduce tuberculosis in high-burden settings: A study of adaptive decision making. Epidemics 2022, 38: 100540. PMID: 35093849, PMCID: PMC8983993, DOI: 10.1016/j.epidem.2022.100540.Peer-Reviewed Original ResearchConceptsHigh-burden settingsTB casesTB prevalenceChest radiographyAdditional TB casesCase-finding yieldTB prevalence estimatesHigh-burden populationsCommunity-randomized trialNumber of screeningsTB controlXpert UltraScreening roundNotification ratesPrevalence estimatesTuberculosisPrevalenceDigital chest radiographyScreeningTrialsInterventionRadiography
2016
The transmission of Mycobacterium tuberculosis in high burden settings
Yates TA, Khan PY, Knight GM, Taylor JG, McHugh TD, Lipman M, White RG, Cohen T, Cobelens FG, Wood R, Moore DA, Abubakar I. The transmission of Mycobacterium tuberculosis in high burden settings. The Lancet Infectious Diseases 2016, 16: 227-238. PMID: 26867464, DOI: 10.1016/s1473-3099(15)00499-5.Peer-Reviewed Original ResearchConceptsHigh-burden settingsBurden settingsTuberculosis infection controlMycobacterium tuberculosis transmissionEffects of HIVHealth care workersDrug-resistant strainsAntiretroviral therapyPerson transmissionTuberculosis transmissionInfection controlTransmission riskAirborne transmissionMycobacterium tuberculosisWells-Riley equationPresent research prioritiesTransmission dynamicsResearch prioritiesHIVEffective strategyTherapyTuberculosisSettingTrials
2010
Prolonged deferral of antiretroviral therapy in the SAPIT trial: Did we need a clinical trial to tell us that this would increase mortality?
Boulle A, Clayden P, Cohen K, Cohen T, Conradie F, Dong K, Geffen N, Grimwood A, Hurtado R, Kenyon C, Lawn S, Maartens G, Meintjes G, Mendelson M, Murray M, Rangaka M, Sanne I, Spencer D, Taljaard J, Variava E, Venter WD, Wilson D. Prolonged deferral of antiretroviral therapy in the SAPIT trial: Did we need a clinical trial to tell us that this would increase mortality? South African Medical Journal 2010, 100: 566,568,570-571. PMID: 20822639, DOI: 10.7196/samj.4434.Peer-Reviewed Original Research