2021
Bayesian evidence synthesis to estimate subnational TB incidence: An application in Brazil
Chitwood MH, Pelissari DM, da Silva G, Bartholomay P, Rocha MS, Sanchez M, Arakaki-Sanchez D, Glaziou P, Cohen T, Castro MC, Menzies NA. Bayesian evidence synthesis to estimate subnational TB incidence: An application in Brazil. Epidemics 2021, 35: 100443. PMID: 33676092, PMCID: PMC8252152, DOI: 10.1016/j.epidem.2021.100443.Peer-Reviewed Original ResearchConceptsTB incidenceFraction of casesUntreated active diseaseIncident TB casesTB control programsLocal disease burdenIncident TBActive diseaseTB burdenTB casesTB outcomesTB notificationsDisease burdenBayesian evidence synthesisCase detectionIncidenceEvidence synthesisAverage annual increaseControl programsBurdenAnnual rateAnnual increaseFraction of individualsAverage annual rateSources of bias
2015
Evaluating the potential impact of enhancing HIV treatment and tuberculosis control programmes on the burden of tuberculosis
Chindelevitch L, Menzies NA, Pretorius C, Stover J, Salomon JA, Cohen T. Evaluating the potential impact of enhancing HIV treatment and tuberculosis control programmes on the burden of tuberculosis. Journal Of The Royal Society Interface 2015, 12: 20150146. PMID: 25878131, PMCID: PMC4424692, DOI: 10.1098/rsif.2015.0146.Peer-Reviewed Original ResearchConceptsAntiretroviral therapyTB incidenceTB burdenBurden of tuberculosisTuberculosis Control ProgrammePotential epidemiological impactART eligibilityMortality benefitTB programsHIV treatmentTB prevalenceTuberculosis incidenceEpidemiological impactART useProgram improvementHIVTreatment effectivenessIncidenceMortalityGreater reductionBurdenTBSaharan AfricaControl programsEligibility
2014
Changing Patterns of Spatial Clustering of Schistosomiasis in Southwest China between 1999–2001 and 2007–2008: Assessing Progress toward Eradication after the World Bank Loan Project
Hu Y, Xiong C, Zhang Z, Luo C, Cohen T, Gao J, Zhang L, Jiang Q. Changing Patterns of Spatial Clustering of Schistosomiasis in Southwest China between 1999–2001 and 2007–2008: Assessing Progress toward Eradication after the World Bank Loan Project. International Journal Of Environmental Research And Public Health 2014, 11: 701-712. PMID: 24394217, PMCID: PMC3924469, DOI: 10.3390/ijerph110100701.Peer-Reviewed Original Research
2013
Identifying dynamic tuberculosis case-finding policies for HIV/TB coepidemics
Yaesoubi R, Cohen T. Identifying dynamic tuberculosis case-finding policies for HIV/TB coepidemics. Proceedings Of The National Academy Of Sciences Of The United States Of America 2013, 110: 9457-9462. PMID: 23690585, PMCID: PMC3677479, DOI: 10.1073/pnas.1218770110.Peer-Reviewed Original ResearchConceptsUndiagnosed casesHigh-burden settingsSmear-negative casesTB control programsDuration of roundsBurden settingsTB suspectsTB transmissionAggressive approachOnward transmissionIncremental yieldPopulation healthIncremental benefitInfectious individualsDiagnostic toolControl programsICFPassive caseSymptomsCasesSettingDiagnosis
2011
Spontaneous Emergence of Multiple Drug Resistance in Tuberculosis before and during Therapy
Colijn C, Cohen T, Ganesh A, Murray M. Spontaneous Emergence of Multiple Drug Resistance in Tuberculosis before and during Therapy. PLOS ONE 2011, 6: e18327. PMID: 21479171, PMCID: PMC3068161, DOI: 10.1371/journal.pone.0018327.Peer-Reviewed Original ResearchConceptsMultiple drug resistanceDrug resistanceInitial treatment regimensTB control programsAnti-TB drugsDrug-resistant formsEmergence of resistanceFunctional monotherapyTreatment regimensCombination therapyTB strainsTuberculosis treatmentTherapy rangeM. tbTB bacilliMultidrug resistanceM. tuberculosisDifferent antibioticsTherapyTuberculosisInfected hostControl programsResistant formsTBMonotherapy
2008
Challenges in Estimating the Total Burden of Drug-resistant Tuberculosis
Cohen T, Colijn C, Wright A, Zignol M, Pym A, Murray M. Challenges in Estimating the Total Burden of Drug-resistant Tuberculosis. American Journal Of Respiratory And Critical Care Medicine 2008, 177: 1302-1306. PMID: 18369201, PMCID: PMC2720088, DOI: 10.1164/rccm.200801-175pp.Peer-Reviewed Original ResearchConceptsDrug-resistant tuberculosisDrug resistance surveillanceHIV/TB coinfectionAnti-Tuberculosis Drug Resistance SurveillanceResistance surveillanceSentinel site surveillanceBurden of tuberculosisMultidrug-resistant diseaseMultidrug-resistant tuberculosisTB control programsTB coinfectionTB casesHigh burdenMethodologic obstaclesSurveillance studyNew casesTotal burdenTuberculosisLaboratory capacityBurdenSurveillanceControl programsDiagnostic technologiesRecent recognitionTrue extent
2004
Modeling epidemics of multidrug-resistant M. tuberculosis of heterogeneous fitness
Cohen T, Murray M. Modeling epidemics of multidrug-resistant M. tuberculosis of heterogeneous fitness. Nature Medicine 2004, 10: 1117-1121. PMID: 15378056, PMCID: PMC2652755, DOI: 10.1038/nm1110.Peer-Reviewed Original ResearchConceptsDrug-sensitive strainsMDR strainsMultidrug resistanceMultidrug-resistant M. tuberculosisM. tuberculosisMultidrug-resistant tuberculosisTuberculosis control effortsEmergence of resistanceTB controlFuture burdenMDR diseaseMDRTB strainsEpidemiological measuresTuberculosisMDRSmall subpopulationMDRTBControl programsBurdenSingle locus mutationsSequential acquisitionDisease