2002
Correlates of Nontransmission in US Women at High Risk of Human Immunodeficiency Virus Type 1 Infection through Sexual Exposure
Skurnick JH, Palumbo P, DeVico A, Shacklett BL, Valentine FT, Merges M, Kamin-Lewis R, Mestecky J, Denny T, Lewis GK, Lloyd J, Praschunus R, Baker A, Nixon DF, Stranford S, Gallo R, Vermund SH, Louria DB. Correlates of Nontransmission in US Women at High Risk of Human Immunodeficiency Virus Type 1 Infection through Sexual Exposure. The Journal Of Infectious Diseases 2002, 185: 428-438. PMID: 11865394, PMCID: PMC2743095, DOI: 10.1086/338830.Peer-Reviewed Original ResearchConceptsSexual exposureSuppressive activityHuman immunodeficiency virus type 1 (HIV-1) infectionHigher CD8 cell countsHIV-1-suppressive activitySingle-cell cytokine productionHuman immunodeficiency virus type 1Macrophage inflammatory protein-1 betaVirus type 1 infectionHIV-positive male partnersInflammatory protein-1 betaMale partnersImmunodeficiency virus type 1CD4 cell responseCD8 cell countsHIV-positive donorsHIV-positive partnerHIV-negative partnersType 1 infectionInterferon-gamma secretionHIV-suppressive activityVirus type 1Apparent protective roleHIV antigenLocal antibodies
2000
T-Lymphocyte Subsets in HIV-Infected and High-Risk HIV-Uninfected Adolescents: Retention of Naive T Lymphocytes in HIV-Infected Adolescents
Douglas SD, Rudy B, Muenz L, Starr SE, Campbell DE, Wilson C, Holland C, Crowley-Nowick P, Vermund SH. T-Lymphocyte Subsets in HIV-Infected and High-Risk HIV-Uninfected Adolescents: Retention of Naive T Lymphocytes in HIV-Infected Adolescents. JAMA Pediatrics 2000, 154: 375-380. PMID: 10768676, DOI: 10.1001/archpedi.154.4.375.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentCD4 Lymphocyte CountCD8-Positive T-LymphocytesFemaleHIV InfectionsHumansMaleT-Lymphocyte SubsetsVirus ReplicationConceptsHIV-negative youthHuman immunodeficiency virus-infected adolescentsT lymphocyte subsetsNaive CD8Total CD4Immune systemCell countHIV infectionAdolescent careAdolescent Medicine HIV/AIDS Research NetworkHuman immunodeficiency virus (HIV) infectionHealth ProjectActive antiretroviral therapyCohort of HIVPercentage of CD4HIV-negative controlsHIV-positive subjectsImmunodeficiency virus infectionAIDS Research NetworkHigh-risk HIVT lymphocyte responsesHIV-negative adolescentsNaive T lymphocytesMemory cell populationsSignificant increase