Chromosome-Wide Analysis of Gene Function by RNA Interference in the African Trypanosome
Subramaniam C, Veazey P, Redmond S, Hayes-Sinclair J, Chambers E, Carrington M, Gull K, Matthews K, Horn D, Field M. Chromosome-Wide Analysis of Gene Function by RNA Interference in the African Trypanosome. MSphere 2006, 5: 1539-1549. PMID: 16963636, PMCID: PMC1563588, DOI: 10.1128/ec.00141-06.Peer-Reviewed Original ResearchConceptsOpen reading frameRNA interferenceGene functionChromosome IT. bruceiDrug targetsChromosome-wide analysisBloodstream form parasitesCell cycle progressionPotential drug targetsNew drug targetsTrypanosome genomeGrowth defectOrder KinetoplastidaGenome sequenceAffected cell growthI geneParasite biologyReading frameGene productsTrypanosoma bruceiBasic biologyParasitic organismsAfrican trypanosomesCycle progression