2023
Sedation in Pediatric Imaging.
Merchant S, Nadkarni P. Sedation in Pediatric Imaging. RadioGraphics 2023, 43: e220168. PMID: 36490207, DOI: 10.1148/rg.220168.Peer-Reviewed Original Research
2021
Overcoming the Patent Gap: A Guide to Patenting for Plastic Surgeons
Kisyova R, Kannan R, Nadkarni P, Chandawarkar R. Overcoming the Patent Gap: A Guide to Patenting for Plastic Surgeons. Plastic & Reconstructive Surgery 2021, 148: 908-917. PMID: 34550948, DOI: 10.1097/prs.0000000000008369.Peer-Reviewed Original Research
2019
Machine Learning in Relation to Emergency Medicine Clinical and Operational Scenarios: An Overview
Lee S, Mohr N, Street W, Nadkarni P. Machine Learning in Relation to Emergency Medicine Clinical and Operational Scenarios: An Overview. Western Journal Of Emergency Medicine 2019, 20: 219-227. PMID: 30881539, PMCID: PMC6404711, DOI: 10.5811/westjem.2019.1.41244.Peer-Reviewed Original ResearchConceptsNatural language processingHealth informaticsMachine-learning algorithmsHealth informatics toolsArtificial intelligenceMachine learningLanguage processingVital technologyInformaticsInformatics toolsEmergency careOperational scenariosEmergency medicineCurrent stateHealthcare providersClinical useHealthcare settingsIntelligencePractice changeMachineAlgorithmToolEM cliniciansPowerful toolProminent development
2018
PCORnet Antibiotics and Childhood Growth Study: Process for Cohort Creation and Cohort Description
Block J, Bailey L, Gillman M, Lunsford D, Boone-Heinonen J, Cleveland L, Finkelstein J, Horgan C, Jay M, Reynolds J, Sturtevant J, Forrest C, Group P, Adams W, Appelhans B, Brickman A, Bian J, Daley M, Davidson A, Dempsey A, Dugas L, Eneli I, Fitzpatrick S, Heerman W, Horberg M, Hsia D, Ingber J, Isasi C, Janicke D, Kane D, Kharbanda E, Meltzer D, Messito M, Nadkarni P, O'Bryan K, Peay H, Puro J, Ranade D, Rao G, Tirado-Ramos A, Rayas M, Razzaghi H, Ricket I, Rosenman M, Siegel R, Solomonides T, Taveras E, Taylor B, Tolia V, Willis Z, VanWormer J, Wysocki T, Zhou X. PCORnet Antibiotics and Childhood Growth Study: Process for Cohort Creation and Cohort Description. Academic Pediatrics 2018, 18: 569-576. PMID: 29477481, PMCID: PMC9746871, DOI: 10.1016/j.acap.2018.02.008.Peer-Reviewed Original ResearchConceptsAntibiotic prescriptionsAntibiotic useObservational studySex-specific body mass indexCohort inclusion criteriaEarly antibiotic useSame-day heightSingle antibiotic prescriptionsBody mass indexLongitudinal observational studyClinical Research NetworkBroad-spectrum antibioticsMonths of agePCORnet common data modelCohort creationSevere obesityNational PatientMass indexCohort descriptionObesity prevalenceInclusion criteriaCohort characteristicsHealth care dataCare dataClinical research
2016
Quality of EHR data extractions for studies of preterm birth in a tertiary care center: guidelines for obtaining reliable data
Knake L, Ahuja M, McDonald E, Ryckman K, Weathers N, Burstain T, Dagle J, Murray J, Nadkarni P. Quality of EHR data extractions for studies of preterm birth in a tertiary care center: guidelines for obtaining reliable data. BMC Pediatrics 2016, 16: 59. PMID: 27130217, PMCID: PMC4851819, DOI: 10.1186/s12887-016-0592-z.Peer-Reviewed Original ResearchConceptsEHR data extractionElectronic health recordsWhite blood cell countTertiary care centerData extractionBlood cell countInitial hemoglobinNeonatal recordsChart reviewFuture study designsPreterm birthChart extractionGestational ageOutside hospitalManual data abstractionBirth weightCare centerDirect bilirubinLaboratory valuesCell countBirth dataStudy designHealth recordsManual abstractionGuidelines
2014
The Greater Plains Collaborative: a PCORnet Clinical Research Data Network
Waitman L, Aaronson L, Nadkarni P, Connolly D, Campbell J. The Greater Plains Collaborative: a PCORnet Clinical Research Data Network. Journal Of The American Medical Informatics Association 2014, 21: 637-641. PMID: 24778202, PMCID: PMC4078294, DOI: 10.1136/amiajnl-2014-002756.Peer-Reviewed Original ResearchConceptsMedical CenterMercy HospitalTranslational Science Award initiativeChildren's Mercy HospitalTexas Southwestern Medical CenterHigh prevalence disordersMinnesota Academic Health CenterAmyotrophic lateral sclerosisKansas Medical CenterSouthwestern Medical CenterHealth Sciences CenterTexas Health Science CenterNebraska Medical CenterHealth centersBreast cancerLateral sclerosisRare diseaseAcademic health centersMarshfield ClinicMedical CollegeDiverse populationsSclerosisScience CenterClinicHospital
2013
Radiation exposure and breast cancer: lessons from Chernobyl.
Ogrodnik A, Hudon T, Nadkarni P, Chandawarkar R. Radiation exposure and breast cancer: lessons from Chernobyl. Connecticut Medicine 2013, 77: 227-34. PMID: 23691737.Peer-Reviewed Original Research
2011
Web-browser encryption of personal health information
Morse R, Nadkarni P, Schoenfeld D, Finkelstein D. Web-browser encryption of personal health information. BMC Medical Informatics And Decision Making 2011, 11: 70. PMID: 22073940, PMCID: PMC3276430, DOI: 10.1186/1472-6947-11-70.Peer-Reviewed Original ResearchConceptsPersonal health informationRemote data entryWeb browserSensitive informationData centersHealth informationData entryHealth recordsUnprecedented amountPatient dataPatient confidentialityFinancial lossesClinical dataInformationMedical conditionsEncryptionServerBrowserClinical researchEffective medical practiceRange of situationsConfidentialityAccessSystemMedical practiceOvercoming barriers to NLP for clinical text: the role of shared tasks and the need for additional creative solutions
Chapman W, Nadkarni P, Hirschman L, D'Avolio L, Savova G, Uzuner O. Overcoming barriers to NLP for clinical text: the role of shared tasks and the need for additional creative solutions. Journal Of The American Medical Informatics Association 2011, 18: 540-543. PMID: 21846785, PMCID: PMC3168329, DOI: 10.1136/amiajnl-2011-000465.Peer-Reviewed Original ResearchPretraining and Posttraining Assessment of Residents' Performance in the Fourth Accreditation Council for Graduate Medical Education Competency: Patient Communication Skills
Chandawarkar RY, Ruscher KA, Krajewski A, Garg M, Pfeiffer C, Singh R, Longo WE, Kozol RA, Lesnikoski B, Nadkarni P. Pretraining and Posttraining Assessment of Residents' Performance in the Fourth Accreditation Council for Graduate Medical Education Competency: Patient Communication Skills. JAMA Surgery 2011, 146: 916-921. PMID: 21844435, DOI: 10.1001/archsurg.2011.167.Peer-Reviewed Original ResearchConceptsPatient communication skillsStandardized patient instructorsCancer scoreRating Scale scoresBreast cancer scoreMaster Interview Rating ScalePatient instructorsResidents' communication skillsInstitutional review boardGeneral surgery residentsMimic patientsRectal cancerProspective studyScale scoreSurgical residents' abilityPatient communicationMedian scoreCommunication skillsReview boardBaseline surveyRating ScaleGeneral communication skillsSurgery residentsGraduate Medical Education competenciesRank testData standards for clinical research data collection forms: current status and challenges
Richesson R, Nadkarni P. Data standards for clinical research data collection forms: current status and challenges. Journal Of The American Medical Informatics Association 2011, 18: 341-346. PMID: 21486890, PMCID: PMC3078665, DOI: 10.1136/amiajnl-2011-000107.Peer-Reviewed Original ResearchConceptsClinical Research InformaticsStandards adoptionWorkflow supportStructured data collectionData itemsResearch informaticsData standardsTool requirementsStandards effortsSuch toolsTerminological standardsResearch data collectionClinical research applicationsContent standardsData collectionInteroperabilityCase report formsResearch applicationsAdoptionInformaticsResearch activitiesRetrievalToolFormal relationshipReuse
2010
Implementing description-logic rules for SNOMED-CT attributes through a table-driven approach
Nadkarni PM, Marenco LA. Implementing description-logic rules for SNOMED-CT attributes through a table-driven approach. Journal Of The American Medical Informatics Association 2010, 17: 182-184. PMID: 20190061, PMCID: PMC3000783, DOI: 10.1136/jamia.2009.001792.Peer-Reviewed Original Research
2009
Automated Database Mediation Using Ontological Metadata Mappings
Marenco L, Wang R, Nadkarni P. Automated Database Mediation Using Ontological Metadata Mappings. Journal Of The American Medical Informatics Association 2009, 16: 723-737. PMID: 19567801, PMCID: PMC2744723, DOI: 10.1197/jamia.m3031.Peer-Reviewed Original ResearchConceptsCross-database queriesHigh-level rulesEnforcement of constraintsDatabase MediationDatabase federationsDatabase ontologyExtended metadataGranularity levelsMetadata mappingBiomedical ontologiesDifferent granularitiesFramework simplifiesCategories of dataMaintenance of systemsMapping rulesQueriesDatabase informationGranularity of representationGlobal vocabularyOntologyGranularityIntegrator systemMetadataDatabaseSNOMED
2008
Common Familial Colorectal Cancer Linked to Chromosome 7q31: A Genome-Wide Analysis
Neklason D, Kerber R, Nilson D, Anton-Culver H, Schwartz A, Griffin C, Lowery J, Schildkraut J, Evans J, Tomlinson G, Strong L, Miller A, Stopfer J, Finkelstein D, Nadkarni P, Kasten C, Mineau G, Burt R. Common Familial Colorectal Cancer Linked to Chromosome 7q31: A Genome-Wide Analysis. Cancer Research 2008, 68: 8993-8997. PMID: 18974144, PMCID: PMC2927856, DOI: 10.1158/0008-5472.can-08-1376.Peer-Reviewed Original ResearchConceptsGenetic regionsLinkage analysisGenome-wide analysisFamilial cancer genesNovel susceptibility genesNonparametric linkage analysisShort tandem repeat markersCommon Familial Colorectal CancerFine mappingRepeat markersTandem repeat markersCancer genesChromosome 7q31Odds (LOD) scoreGenesSusceptibility genesSignificant linkagePenetrant genesDNA samplesFamilial colorectal cancerRelative pairsLociCancer onsetColorectal cancer onsetCancer syndromes
2007
SenseLab: new developments in disseminating neuroscience information
Crasto CJ, Marenco LN, Liu N, Morse TM, Cheung KH, Lai PC, Bahl G, Masiar P, Lam HY, Lim E, Chen H, Nadkarni P, Migliore M, Miller PL, Shepherd GM. SenseLab: new developments in disseminating neuroscience information. Briefings In Bioinformatics 2007, 8: 150-162. PMID: 17510162, PMCID: PMC2756159, DOI: 10.1093/bib/bbm018.Peer-Reviewed Original ResearchInteroperability Across Neuroscience Databases
Marenco L, Nadkarni P, Martone M, Gupta A. Interoperability Across Neuroscience Databases. Methods In Molecular Biology 2007, 401: 23-36. PMID: 18368358, DOI: 10.1007/978-1-59745-520-6_2.Peer-Reviewed Original ResearchConceptsHuman Brain ProjectData interoperabilityData sharingNeuroscience databasesData heterogeneityCurrent data sharingSemantic data modelDatabase interoperabilityWeb servicesMetadata repositoryRobust interoperabilityMetadata annotationData integrationData modelInteroperabilityBrain ProjectInformation frameworkNeuroscience informationIntegration mechanismsSharingConstant creationDomain changesNeuroscience initiativesServicesMultidisciplinary nature
2006
Guidelines for the effective use of entity–attribute–value modeling for biomedical databases
Dinu V, Nadkarni P. Guidelines for the effective use of entity–attribute–value modeling for biomedical databases. International Journal Of Medical Informatics 2006, 76: 769-779. PMID: 17098467, PMCID: PMC2110957, DOI: 10.1016/j.ijmedinf.2006.09.023.Peer-Reviewed Original ResearchPivoting approaches for bulk extraction of Entity–Attribute–Value data
Dinu V, Nadkarni P, Brandt C. Pivoting approaches for bulk extraction of Entity–Attribute–Value data. Computer Methods And Programs In Biomedicine 2006, 82: 38-43. PMID: 16556470, DOI: 10.1016/j.cmpb.2006.02.001.Peer-Reviewed Original ResearchConceptsEntity attributesClinical study data management systemsData management systemNumber of attributesDatabase serverHash tableClinical patient dataValue dataManagement systemAlternative algorithmsPatient dataSQLServerRepositoryAlgorithmComplex approachFormatDataAttributesParameter formatOne-columnExtractionAnalytical programPerformanceMemoryInformatics tools to improve clinical research study implementation
Brandt CA, Argraves S, Money R, Ananth G, Trocky NM, Nadkarni PM. Informatics tools to improve clinical research study implementation. Contemporary Clinical Trials 2006, 27: 112-122. PMID: 16388990, DOI: 10.1016/j.cct.2005.11.013.Peer-Reviewed Original Research
2005
Translating pharmacogenomics discoveries into clinical practice: the role of curated databases
Nadkarni P, Wiepert M. Translating pharmacogenomics discoveries into clinical practice: the role of curated databases. Pharmacogenomics 2005, 6: 451-454. PMID: 16013993, PMCID: PMC2982678, DOI: 10.2217/14622416.6.5.451.Peer-Reviewed Original Research