Modulation of Neonatal Neutrophil Function by Pentoxifylline
Krause P, Maderazo E, Contrino J, Eisenfeld L, Herson V, Greca N, Bannon P, Kreutzer D. Modulation of Neonatal Neutrophil Function by Pentoxifylline. Pediatric Research 1991, 29: 123-127. PMID: 2014147, DOI: 10.1203/00006450-199102000-00002.Peer-Reviewed Original ResearchConceptsPMN functionNitroblue tetrazolium reductionImpaired PMN functionsNeonatal neutrophil functionTetrazolium reductionTreatment of infectionsPolymorphonuclear leukocyte chemotaxisF-actin contentDose-dependent effectPotential clinical useCertain disease processesSimilar dose-dependent responseDose-dependent responseNeutrophil functionNewborn infantsPMN activityPMN deformabilityPMN chemotaxisDisease processPentoxifyllineLeukocyte chemotaxisMethylxanthine pentoxifyllinePhagocytic activityNeonatesClinical use