1991
Modulation of Neonatal Neutrophil Function by Pentoxifylline
Krause P, Maderazo E, Contrino J, Eisenfeld L, Herson V, Greca N, Bannon P, Kreutzer D. Modulation of Neonatal Neutrophil Function by Pentoxifylline. Pediatric Research 1991, 29: 123-127. PMID: 2014147, DOI: 10.1203/00006450-199102000-00002.Peer-Reviewed Original ResearchConceptsPMN functionNitroblue tetrazolium reductionImpaired PMN functionsNeonatal neutrophil functionTetrazolium reductionTreatment of infectionsPolymorphonuclear leukocyte chemotaxisF-actin contentDose-dependent effectPotential clinical useCertain disease processesSimilar dose-dependent responseDose-dependent responseNeutrophil functionNewborn infantsPMN activityPMN deformabilityPMN chemotaxisDisease processPentoxifyllineLeukocyte chemotaxisMethylxanthine pentoxifyllinePhagocytic activityNeonatesClinical use
1989
Characterization of Nonmotile Neutrophil Subpopulations in Neonates and Adults
Krause P, Kreutzer D, Eisenfeld L, Herson V, Weisman S, Bannon P, Greca N. Characterization of Nonmotile Neutrophil Subpopulations in Neonates and Adults. Pediatric Research 1989, 25: 519-524. PMID: 2717268, DOI: 10.1203/00006450-198905000-00019.Peer-Reviewed Original ResearchMeSH KeywordsAdultAntibodies, MonoclonalChemotaxis, LeukocyteFetal BloodHumansInfant, NewbornNeutrophilsPhagocytosisConceptsPMN subpopulationPolymorphonuclear leukocytesPMN motilityAdult polymorphonuclear leukocytesMost polymorphonuclear leukocytesMicropore filtersNeutrophil subpopulationsHomogeneous populationPhagocytic functionNeonatesChemotactic stimuliMAbsSubpopulationsAdultsPMN precursorsPresent studyHigh percentageMotilityCellsPrevious studiesPopulationLeukocytesAntibodies
1987
The Effect of Betamethasone on Neonatal Neutrophil Chemotaxis
Fuenfer M, Herson V, Raye J, Woronick C, Eisenfeld L, Ingardia C, Block C, Krause P. The Effect of Betamethasone on Neonatal Neutrophil Chemotaxis. Pediatric Research 1987, 22: 150-153. PMID: 3658539, DOI: 10.1203/00006450-198708000-00009.Peer-Reviewed Original ResearchConceptsEffect of betamethasoneBacterial infectionsNewborn infantsPMN functionMaternal glucocorticoid administrationNeonatal PMN functionFetal lung maturationMigration of PMNRandom migrationConcentrations of betamethasonePMN random migrationSignificant clinical importanceBetamethasone administrationGlucocorticoid administrationPregnant womenLung maturationNeutrophil functionStandard doseCord bloodNeutrophil chemotaxisAntiinflammatory agentsClinical importanceImportant causeImmune systemBetamethasone
1982
Abnormalities of neutrophil adherence in newborns.
Krause P, Maderazo E, Scroggs M. Abnormalities of neutrophil adherence in newborns. Pediatrics 1982, 69: 184-7. PMID: 7058092, DOI: 10.1542/peds.69.2.184.Peer-Reviewed Original ResearchConceptsPMN adherenceNeutrophil adherencePolymorphonuclear neutrophil (PMN) adherenceHealthy term newbornsSerious bacterial infectionsSusceptibility of neonatesTerm newbornsNeonatal PMNNeonatal serumNylon woolAdult serumHumoral inhibitorAdult PMNBacterial infectionsGlass adherenceNormal childrenGood healthAdherenceGreater reductionPMNNewbornsSerumCellular defectsAdultsChildren