2009
Dermatologic Changes Induced by Repeated Ixodes scapularis Bites and Implications for Prevention of Tick-Borne Infection
Krause PJ, Grant-Kels JM, Tahan SR, Dardick KR, Alarcon-Chaidez F, Bouchard K, Visini C, Deriso C, Foppa IM, Wikel S. Dermatologic Changes Induced by Repeated Ixodes scapularis Bites and Implications for Prevention of Tick-Borne Infection. Vector-Borne And Zoonotic Diseases 2009, 9: 603-610. PMID: 19196014, PMCID: PMC2883515, DOI: 10.1089/vbz.2008.0091.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsBites and StingsDisease Models, AnimalEctoparasitic InfestationsHumansIxodesMiceMice, Inbred BALB CTick-Borne DiseasesConceptsBALB/c miceVascular dilatationInflammatory cellsC miceSkin biopsiesTick-borne pathogen transmissionI. scapularis nymphsTick attachmentScapularis nymphsSimilar histologic patternTick-Borne InfectionsMechanism of preventionBorrelia burgdorferi transmissionDermatologic changesHistologic patternTick exposureBite siteImmune hostHistopathologic reactionsTick-borne pathogensPathogen transmissionTick immunityCellular changesMiceMarked increase
2006
Confirmation of Tick Bite by Detection of Antibody to Ixodes Calreticulin Salivary Protein▿
Alarcon-Chaidez F, Ryan R, Wikel S, Dardick K, Lawler C, Foppa IM, Tomas P, Cushman A, Hsieh A, Spielman A, Bouchard KR, Dias F, Aslanzadeh J, Krause PJ. Confirmation of Tick Bite by Detection of Antibody to Ixodes Calreticulin Salivary Protein▿. MSphere 2006, 13: 1217-1222. PMID: 16928887, PMCID: PMC1656538, DOI: 10.1128/cvi.00201-06.Peer-Reviewed Original ResearchConceptsEnzyme-linked immunosorbent assayImmune responseTick exposureBALB/c miceC3H/HeNTick-borne infectionsHuman granulocytic anaplasmosisDetection of antibodiesLaboratory markersAntibody responseC miceTick biteSalivary proteinsObjective evidenceLyme diseaseImmunosorbent assayGranulocytic anaplasmosisHuman babesiosisSalivary glandsIxodes ticksAntibodiesBlood mealSame assayMiceSerum
2005
Hypersensitivity to Ticks and Lyme Disease Risk
Burke G, Wikel SK, Spielman A, Telford SR, McKay K, Krause PJ, . Hypersensitivity to Ticks and Lyme Disease Risk. Emerging Infectious Diseases 2005, 11: 36-41. PMID: 15705320, PMCID: PMC3294369, DOI: 10.3201/eid1101.040303.Peer-Reviewed Original ResearchConceptsTick biteLyme diseaseLyme disease-endemic regionsNymphal Ixodes scapularis ticksLyme disease infectionDisease-endemic regionsCutaneous hypersensitivityIxodes scapularis ticksStudy participantsDisease riskPrior exposureDiseaseBorrelia burgdorferiFrequent exposureScapularis ticksBiteItchLyme disease riskHypersensitivityVector ticksTicksPrevious yearExposureDisease infectionResidents
2002
Ehrlichiosis in children
Lantos P, Krause PJ. Ehrlichiosis in children. Seminars In Pediatric Infectious Diseases 2002, 13: 249-256. PMID: 12491230, DOI: 10.1053/spid.2002.127200.Peer-Reviewed Original Research