1991
Modulation of Neonatal Neutrophil Function by Pentoxifylline
Krause P, Maderazo E, Contrino J, Eisenfeld L, Herson V, Greca N, Bannon P, Kreutzer D. Modulation of Neonatal Neutrophil Function by Pentoxifylline. Pediatric Research 1991, 29: 123-127. PMID: 2014147, DOI: 10.1203/00006450-199102000-00002.Peer-Reviewed Original ResearchConceptsPMN functionNitroblue tetrazolium reductionImpaired PMN functionsNeonatal neutrophil functionTetrazolium reductionTreatment of infectionsPolymorphonuclear leukocyte chemotaxisF-actin contentDose-dependent effectPotential clinical useCertain disease processesSimilar dose-dependent responseDose-dependent responseNeutrophil functionNewborn infantsPMN activityPMN deformabilityPMN chemotaxisDisease processPentoxifyllineLeukocyte chemotaxisMethylxanthine pentoxifyllinePhagocytic activityNeonatesClinical use
1989
Enhancement of neutrophil function for treatment of neonatal infections
KRAUSE P, HERSON V, EISENFELD L, JOHNSON G. Enhancement of neutrophil function for treatment of neonatal infections. The Pediatric Infectious Disease Journal 1989, 8: 382-389. PMID: 2664694, DOI: 10.1097/00006454-198906000-00011.Peer-Reviewed Original ResearchConceptsNewborn infantsRisk of morbidityFresh frozen plasmaMaximum therapeutic benefitHost defense mechanismsNeonatal infectionImportant therapyNeutrophil functionFrozen plasmaPMN functionTherapeutic benefitAdult PMNInfectionFurther studiesInfantsNew antibioticsDefense mechanismsTransfusionMorbidityNeonatesTherapyMortalityAdministrationImpairmentAntibodies
1987
The Effect of Betamethasone on Neonatal Neutrophil Chemotaxis
Fuenfer M, Herson V, Raye J, Woronick C, Eisenfeld L, Ingardia C, Block C, Krause P. The Effect of Betamethasone on Neonatal Neutrophil Chemotaxis. Pediatric Research 1987, 22: 150-153. PMID: 3658539, DOI: 10.1203/00006450-198708000-00009.Peer-Reviewed Original ResearchConceptsEffect of betamethasoneBacterial infectionsNewborn infantsPMN functionMaternal glucocorticoid administrationNeonatal PMN functionFetal lung maturationMigration of PMNRandom migrationConcentrations of betamethasonePMN random migrationSignificant clinical importanceBetamethasone administrationGlucocorticoid administrationPregnant womenLung maturationNeutrophil functionStandard doseCord bloodNeutrophil chemotaxisAntiinflammatory agentsClinical importanceImportant causeImmune systemBetamethasone
1985
1094 THE EFFECT OF BETAMETHASONE ON THE CHEMOTACTIC RESPONSE OF NEONATAL NEUTROPHILS
Fuenfer M, Ingardia C, Raye J, Block C, Krause P. 1094 THE EFFECT OF BETAMETHASONE ON THE CHEMOTACTIC RESPONSE OF NEONATAL NEUTROPHILS. Pediatric Research 1985, 19: 293-293. DOI: 10.1203/00006450-198504000-01124.Peer-Reviewed Original ResearchEffect of betamethasoneMaternal steroid administrationPerinatal bacterial infectionHealthy term neonatesFetal lung maturationRisk of infectionSteroid administrationTerm neonatesHost defense systemNeonatal neutrophilsLung maturationNeutrophil functionCord bloodPMN functionNeonatal PMNTherapeutic concentrationsPMN chemokinesisBacterial infectionsBetamethasoneNeonatesPMN motilitySignificant inhibitionRandom migrationMicropore filtersFurther compromise