2021
Babesia microti: Pathogen Genomics, Genetic Variability, Immunodominant Antigens, and Pathogenesis
Puri A, Bajpai S, Meredith S, Aravind L, Krause PJ, Kumar S. Babesia microti: Pathogen Genomics, Genetic Variability, Immunodominant Antigens, and Pathogenesis. Frontiers In Microbiology 2021, 12: 697669. PMID: 34539601, PMCID: PMC8446681, DOI: 10.3389/fmicb.2021.697669.Peer-Reviewed Original ResearchPolymerase chain reactionPerinatal transmissionBlood transfusionModerate diseaseMost infectionsOrgan transplantationImmune evasionBlood smearsImmunodominant antigensHuman babesiosisInfection severityPathogenesisChain reactionPotential roleCell surface proteinsDiseaseDiagnosisHuman diseasesPathogen genomicsBabesiosisIxodid ticksPhylum ApicomplexaTransfusionTransplantationHumans
2013
Chapter 14 Neurological manifestations of human babesiosis
Usmani-Brown S, Halperin JJ, Krause PJ. Chapter 14 Neurological manifestations of human babesiosis. Handbook Of Clinical Neurology 2013, 114: 199-203. PMID: 23829910, DOI: 10.1016/b978-0-444-53490-3.00014-5.Peer-Reviewed Original ResearchConceptsLevel of consciousnessRare complicationBlood transfusionNeurological manifestationsCommon symptomsNeurological dysfunctionFatal diseaseInfectious diseasesIntraerythrocytic protozoaHuman babesiosisDiseaseBabesiosisIxodid ticksTransfusionComplicationsHeadacheDysfunctionLethargyPathogenesisSymptoms
2008
Human Babesiosis
Vannier E, Gewurz BE, Krause PJ. Human Babesiosis. Infectious Disease Clinics Of North America 2008, 22: 469-488. PMID: 18755385, PMCID: PMC3998201, DOI: 10.1016/j.idc.2008.03.010.Peer-Reviewed Original ResearchConceptsBabesial infectionHuman babesiosisCombination of atovaquoneTreatment of choiceSpecific laboratory diagnosisModerate illnessExchange transfusionPolymerase chain reactionSevere diseaseLaboratory diagnosisMorphologic examinationBlood smearsProtozoal parasitesInfectionChain reactionBabesial DNABabesiosisIntraerythrocytic infectionUnited StatesIxodid ticksTransfusionUpper midwestern regionsClindamycinSerologyAzithromycin
2000
Babesiosis
Homer M, Aguilar-Delfin I, Telford S, Krause P, Persing D. Babesiosis. Clinical Microbiology Reviews 2000, 13: 451-469. DOI: 10.1128/cmr.13.3.451.Peer-Reviewed Original ResearchPossible pathogenic mechanismsAppropriate patient managementInfected red blood cellsSpecies of BabesiaMalaria-like diseaseWidespread blood parasitesRed blood cellsSilent infectionEpidemiological descriptionDisease manifestationsPatient managementImmunological responsePear-shaped formsSevere hemolysisDisease processPathogenic mechanismsHematotropic parasitesBabesia microtiBabesial parasitesDiagnostic testsBlood cellsVeterinary impactBabesia speciesGenus BabesiaIxodid ticksBabesiosis
Homer M, Aguilar-Delfin I, Telford S, Krause P, Persing D. Babesiosis. Clinical Microbiology Reviews 2000, 13: 451-469. PMID: 10885987, PMCID: PMC88943, DOI: 10.1128/cmr.13.3.451-469.2000.Peer-Reviewed Original ResearchConceptsSpecies of BabesiaMalaria-like diseaseWidespread blood parasitesPear-shaped formsPossible pathogenic mechanismsAppropriate patient managementInfected red blood cellsHematotropic parasitesVeterinary impactBabesia speciesGenus BabesiaIxodid ticksBabesial parasitesZoonotic diseaseRed blood cellsBabesia divergensSilent infectionAnimal hostsEpidemiological descriptionDisease manifestationsPatient managementImmunological responseSevere hemolysisB. microtiTransmission cycle