2022
Ambient air pollution is associated with vascular disease in Ugandan HIV-positive adolescents
Toe S, Nagy M, Albar Z, Yu J, Sattar A, Nazzinda R, Musiime V, Etajak S, Walyawula F, McComsey G, Atuyambe L, Dirajlal-Fargo S. Ambient air pollution is associated with vascular disease in Ugandan HIV-positive adolescents. AIDS 2022, 36: 863-870. PMID: 35131961, PMCID: PMC9081159, DOI: 10.1097/qad.0000000000003186.Peer-Reviewed Original ResearchConceptsIntima-media thicknessVascular diseaseMonocyte activationCarotid intima-media thicknessSubclinical vascular diseaseHIV-positive adolescentsMarkers of inflammationEffects of HIVCross-sectional studyMultivariable quantile regression modelsMultivariable quantile regressionAmbient air pollutionDaily ambient concentrationsDaily PM2.5 exposureExposure of PM2.5Systemic inflammationMedian ageSoluble CD163Atherosclerotic diseasePlasma markersIntestinal permeabilityCardiovascular diseaseGut integrityHIVPM2.5 exposure
2019
Brief Report: Zinc Supplementation and Inflammation in Treated HIV.
Dirajlal-Fargo S, Yu J, Kulkarni M, Sattar A, Funderburg N, Barkoukis H, Mccomsey G. Brief Report: Zinc Supplementation and Inflammation in Treated HIV. JAIDS Journal Of Acquired Immune Deficiency Syndromes 2019, 82: 275-280. PMID: 31609926, PMCID: PMC6812547, DOI: 10.1097/qai.0000000000002129.Peer-Reviewed Original ResearchConceptsZinc supplementationZinc levelsDouble-arm studyHigh-dose armLow-dose armMedian zinc levelStable antiretroviral therapyMarkers of inflammationYears old peopleTreated HIVAntiretroviral therapyHIV infectionMedian ageClinical comorbiditiesBiomarker levelsMonocyte activationLarge effect sizesHIVInflammationPilot studyPhase ISupplementationDlElemental zincAfrican Americans