2022
Prevalence of Plasmodium falciparum haplotypes associated with resistance to sulfadoxine–pyrimethamine and amodiaquine before and after upscaling of seasonal malaria chemoprevention in seven African countries: a genomic surveillance study
Beshir K, Muwanguzi J, Nader J, Mansukhani R, Traore A, Gamougam K, Ceesay S, Bazie T, Kolie F, Lamine M, Cairns M, Snell P, Scott S, Diallo A, Merle C, NDiaye J, Razafindralambo L, Moroso D, Ouedraogo J, Zongo I, Kessely H, Doumagoum D, Bojang K, Ceesay S, Loua K, Maiga H, Dicko A, Sagara I, Laminou I, Ogboi S, Eloike T, Milligan P, Sutherland C. Prevalence of Plasmodium falciparum haplotypes associated with resistance to sulfadoxine–pyrimethamine and amodiaquine before and after upscaling of seasonal malaria chemoprevention in seven African countries: a genomic surveillance study. The Lancet Infectious Diseases 2022, 23: 361-370. PMID: 36328000, DOI: 10.1016/s1473-3099(22)00593-x.Peer-Reviewed Original ResearchConceptsSeasonal malaria chemopreventionMalaria chemopreventionResistance-associated variantsParasite carriageSurvey-weighted prevalenceMalaria transmission seasonQuantitative PCRPrevalence ratiosP falciparumGenomic surveillance studyChemoprevention drugsBlood samplesSurveillance studyTransmission seasonChemopreventionPlasmodium falciparumAmodiaquinePrevalenceMDR1Variant haplotypeSequencing of isolatesSignificant reductionChildrenPyrimethamineCommunity surveyImpact of seasonal RTS,S/AS01E vaccination plus seasonal malaria chemoprevention on the nutritional status of children in Burkina Faso and Mali
Grant J, Sagara I, Zongo I, Cairns M, Yerbanga R, Diarra M, Zoungrana C, Issiaka D, Nikièma F, Sompougdou F, Tapily A, Kaya M, Haro A, Sanogo K, Sienou A, Traore S, Thera I, Yalcouye H, Kuepfer I, Snell P, Milligan P, Ockenhouse C, Ofori-Anyinam O, Tinto H, Djimde A, Chandramohan D, Greenwood B, Dicko A, Ouédraogo J. Impact of seasonal RTS,S/AS01E vaccination plus seasonal malaria chemoprevention on the nutritional status of children in Burkina Faso and Mali. Malaria Journal 2022, 21: 59. PMID: 35193608, PMCID: PMC8864823, DOI: 10.1186/s12936-022-04077-x.Peer-Reviewed Original ResearchConceptsSeasonal malaria chemopreventionMalaria chemopreventionSevere wastingHigh burdenTransmission seasonCombined groupNutritional statusMalaria transmission seasonNutritional status indicatorsPrevalence of stuntingIncidence of malariaCross-sectional surveyMalaria vaccinationSevere malariaRecent trialsStudy populationAS01ELow prevalenceAnthropometric measurementsChronic malnutritionTreatment groupsChance findingStudy childrenResultsIn 2017Prevalence
2020
High Plasmodium infection intensity in naturally infected malaria vectors in Africa
Bompard A, Da D, Yerbanga S, Morlais I, Awono-Ambéné P, Dabiré R, Ouédraogo J, Lefèvre T, Churcher T, Cohuet A. High Plasmodium infection intensity in naturally infected malaria vectors in Africa. International Journal For Parasitology 2020, 50: 985-996. PMID: 32681932, DOI: 10.1016/j.ijpara.2020.05.012.Peer-Reviewed Original ResearchConceptsOocyst-positive mosquitoesInfectious blood mealEfficacy of transmissionControl of malariaWild malaria vectorsMalaria parasite transmissionCross-sectional surveyInfection loadSalivary gland sporozoitesMalaria vectorsMalaria endemicityNumber of oocystsInfected mosquitoesMalaria transmissionOocyst prevalenceStrong positive associationPrevalencePositive associationBlood mealOocyst loadInfection intensityEpidemiologyEfficacyParasite transmissionIntervention
2018
Effectiveness of a community-based educational programme in reducing the cumulative incidence and prevalence of human Taenia solium cysticercosis in Burkina Faso in 2011–14 (EFECAB): a cluster-randomised controlled trial
Carabin H, Millogo A, Ngowi H, Bauer C, Dermauw V, Koné A, Sahlu I, Salvator A, Preux P, Somé T, Tarnagda Z, Gabriël S, Cissé R, Ouédraogo J, Cowan L, Boncoeur-Martel M, Dorny P, Ganaba R. Effectiveness of a community-based educational programme in reducing the cumulative incidence and prevalence of human Taenia solium cysticercosis in Burkina Faso in 2011–14 (EFECAB): a cluster-randomised controlled trial. The Lancet Global Health 2018, 6: e411-e425. PMID: 29530423, PMCID: PMC5873982, DOI: 10.1016/s2214-109x(18)30027-5.Peer-Reviewed Original ResearchConceptsCumulative incidenceHuman cysticercosisActive cysticercosisHuman Taenia solium cysticercosisCommunity-based educational interventionDrug-free interventionsTaenia solium transmissionCommunity-based educational programTaenia solium cysticercosisLow-resource settingsPrevalence of cysticercosisEligible villagesPrimary outcomeUS National InstitutesSolium transmissionBlood samplesFinal sample sizeControl groupSolium cysticercosisCysticercosisCysticercosis prevalenceRandomisationEducational interventionPrevalenceIncidence
2015
Prevalence of the dhfr and dhps Mutations among Pregnant Women in Rural Burkina Faso Five Years after the Introduction of Intermittent Preventive Treatment with Sulfadoxine-Pyrimethamine
Tahita M, Tinto H, Erhart A, Kazienga A, Fitzhenry R, VanOvermeir C, Rosanas-Urgell A, Ouedraogo J, Guiguemde R, Van geertruyden J, D’Alessandro U. Prevalence of the dhfr and dhps Mutations among Pregnant Women in Rural Burkina Faso Five Years after the Introduction of Intermittent Preventive Treatment with Sulfadoxine-Pyrimethamine. PLOS ONE 2015, 10: e0137440. PMID: 26368675, PMCID: PMC4569438, DOI: 10.1371/journal.pone.0137440.Peer-Reviewed Original ResearchMeSH KeywordsAdultAntimalarialsBurkina FasoDihydropteroate SynthaseDrug CombinationsDrug ResistanceFemaleHumansMalaria, FalciparumMutationPlasmodium falciparumPregnancyPregnancy Trimester, SecondPregnancy Trimester, ThirdPrevalenceProtozoan ProteinsPyrimethamineSulfadoxineTetrahydrofolate DehydrogenaseYoung AdultConceptsIntermittent preventive treatmentPregnant womenPfdhps genesPreventive treatmentAntenatal careSulfadoxine-pyrimethamineThird trimesterDhps mutationsPfdhfr mutationsMalaria infectionMalaria symptomsHealth districtPfdhfr geneBlood samplesSP resistanceI164L mutationEndemic regionsReductase mutationMalaria controlDrug resistancePrevalenceAdverse effectsFive yearsWomenBurkina FasoPlasmodium transmission blocking activities of Vernonia amygdalina extracts and isolated compounds
Abay S, Lucantoni L, Dahiya N, Dori G, Dembo E, Esposito F, Lupidi G, Ogboi S, Ouédraogo R, Sinisi A, Taglialatela-Scafati O, Yerbanga R, Bramucci M, Quassinti L, Ouédraogo J, Christophides G, Habluetzel A. Plasmodium transmission blocking activities of Vernonia amygdalina extracts and isolated compounds. Malaria Journal 2015, 14: 288. PMID: 26208861, PMCID: PMC4513948, DOI: 10.1186/s12936-015-0812-2.Peer-Reviewed Original ResearchConceptsEarly sporogonic stagesOocyst prevalenceVivo transmissionHuman parasite P. falciparumP. berghei parasitesMalaria control toolsAnopheles stephensi mosquitoesEthanolic leaf extractVernonia amygdalina extractPreventive treatmentBerghei parasitesField isolatesAnopheles coluzzii mosquitoesParasite P. falciparumP. falciparumBackgroundMedicinal plantsStephensi mosquitoesPlasmodium transmissionHerbal medicineMurine parasitePlasmodium falciparumLeaf extractPrevalenceCytotoxic effectsSporogonic stagesDynamic of plasmodium falciparum chloroquine resistance transporter gene Pfcrt K76T mutation five years after withdrawal of chloroquine in Burkina Faso
Sondo P, Derra K, Tarnagda Z, Nakanabo S, Zampa O, Kazienga A, Valea I, Sorgho H, Ouedraogo J, Guiguemde T, Tinto H. Dynamic of plasmodium falciparum chloroquine resistance transporter gene Pfcrt K76T mutation five years after withdrawal of chloroquine in Burkina Faso. Pan African Medical Journal 2015, 21: 101. PMID: 26516402, PMCID: PMC4606025, DOI: 10.11604/pamj.2015.21.101.6437.Peer-Reviewed Original Research
2014
Asymptomatic Malaria Infection Affects the Interpretation of Biomarkers of Iron and Vitamin A Status, Even after Adjusting for Systemic Inflammation, but Does Not Affect Plasma Zinc Concentrations among Young Children in Burkina Faso
Wessells K, Hess S, Ouédraogo Z, Rouamba N, Ouédraogo J, Brown K. Asymptomatic Malaria Infection Affects the Interpretation of Biomarkers of Iron and Vitamin A Status, Even after Adjusting for Systemic Inflammation, but Does Not Affect Plasma Zinc Concentrations among Young Children in Burkina Faso. Journal Of Nutrition 2014, 144: 2050-2058. PMID: 25411038, DOI: 10.3945/jn.114.200345.Peer-Reviewed Original ResearchMeSH KeywordsAcute-Phase ProteinsAcute-Phase ReactionAdolescentAnemia, Iron-DeficiencyAsymptomatic DiseasesBiomarkersBurkina FasoChildC-Reactive ProteinCross-Sectional StudiesDietary SupplementsFemaleFerritinsHemoglobinsHumansIron, DietaryLinear ModelsMalariaMaleMicronutrientsNutritional StatusOrosomucoidPrevalenceProteinsRandomized Controlled Trials as TopicRetinol-Binding ProteinsVitamin AVitamin A DeficiencyZincConceptsAcute phase proteinsElevated acute phase proteinsAsymptomatic malaria infectionsMalaria infectionMicronutrient statusBiomarkers of ironSoluble transferrin receptorVitamin A StatusAcute phase responseIndicators of ironPlasma zinc concentrationAsymptomatic malariaAsymptomatic childrenSystemic inflammationMalaria parasitemiaHigh prevalenceA StatusPhase proteinsInterpretation of biomarkersZinc statusIron deficiencyLower RBPHRP2PrevalenceMicronutrient deficiencies
2013
The effects of the acute phase response on biomarkers of iron status differ in the presence of malaria infection
Wessells R, Hess S, Ouedraogo Z, Rouamba N, Erhardt J, Ouedraogo J, Brown K. The effects of the acute phase response on biomarkers of iron status differ in the presence of malaria infection. The FASEB Journal 2013, 27: 107.7-107.7. DOI: 10.1096/fasebj.27.1_supplement.107.7.Peer-Reviewed Original ResearchC-reactive proteinAcute phase responseIron statusAsymptomatic childrenSubclinical inflammationPlasma ferritinMalaria infectionMalarial parasitemiaPhase responseHigh prevalenceHigher geometric meanMalariaPrevalenceAP proteinInflammationChildrenInfectionGrant funding sourcesDeficiencyAGPGeometric meanStatusAntigenemiaBurkina FasoParasitemia
2011
Prevalence of infectious bronchitis and Newcastle disease virus among domestic and wild birds in H5N1 outbreaks areas.
Tarnagda Z, Yougbare I, Kam A, Tahita M, Ouedraogo J. Prevalence of infectious bronchitis and Newcastle disease virus among domestic and wild birds in H5N1 outbreaks areas. The Journal Of Infection In Developing Countries 2011, 5: 565-70. PMID: 21841299, DOI: 10.3855/jidc.1441.Peer-Reviewed Original ResearchConceptsInfectious bronchitis virusNewcastle disease virusAvian influenza virusesPrevalence of IBVInfluenza virusDisease virusH5N1 virusBronchitis virusPrevalence of influenzaPresence of influenzaWild birdsPositive casesBurkina FasoInfectious bronchitisPrevalenceOutbreak areaVirusCloacal swabsInfluenzaTotal RNAH5N1 outbreaksAnimal healthWorld OrganisationLocal chickensSpecific primers
2008
Chloroquine‐resistance molecular markers (Pfcrt T76 and Pfmdr‐1 Y86) and amodiaquine resistance in Burkina Faso
Tinto H, Guekoun L, Zongo I, Guiguemdé R, D’Alessandro U, Ouédraogo J. Chloroquine‐resistance molecular markers (Pfcrt T76 and Pfmdr‐1 Y86) and amodiaquine resistance in Burkina Faso. Tropical Medicine And International Health 2008, 13: 238-240. PMID: 18304270, DOI: 10.1111/j.1365-3156.2007.01995.x.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAmodiaquineAnimalsAntimalarialsBurkina FasoChildChild, PreschoolChloroquineDrug ResistanceHumansInfantInfant, NewbornMalaria, FalciparumMembrane Transport ProteinsMultidrug Resistance-Associated ProteinsMutationPlasmodium falciparumPolymerase Chain ReactionPrevalenceProtozoan ProteinsTreatment FailureTreatment Outcome
2007
Sulfadoxine-pyrimethamine efficacy and selection of Plasmodium falciparum DHFR mutations in Burkina Faso before its introduction as intermittent preventive treatment for pregnant women.
Tinto H, Ouédraogo J, Zongo I, van Overmeir C, van Marck E, Guiguemdé T, D'Alessandro U. Sulfadoxine-pyrimethamine efficacy and selection of Plasmodium falciparum DHFR mutations in Burkina Faso before its introduction as intermittent preventive treatment for pregnant women. American Journal Of Tropical Medicine And Hygiene 2007, 76: 608-13. PMID: 17426157, DOI: 10.4269/ajtmh.2007.76.608.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAnimalsAntimalarialsBurkina FasoChildChild, PreschoolChloroquineDrug Administration ScheduleDrug CombinationsDrug ResistanceFemaleGenotypeHumansInfantMalaria, FalciparumMaleMutationPlasmodium falciparumPregnancyPregnancy Complications, ParasiticPyrimethamineSelection, GeneticSulfadoxineTetrahydrofolate DehydrogenaseConceptsSulfadoxine-pyrimethamine efficacyTriple dhfr mutationDHFR mutationsRecurrent parasitemiaIntermittent preventive treatmentSulfadoxine-pyrimethamine resistanceYears of ageSuch high prevalenceDihydropteroate synthetase (Pfdhps) mutationsPCR-restriction fragment length polymorphismSulfadoxine-pyrimethamineTreatment failurePregnant womenPolymerase chain reactionPreventive treatmentHigh prevalenceNew infectionsChain reactionMutant parasitesPatientsParasitemiaTreatmentFragment length polymorphismPrevalenceEfficacy
2006
Roles of specific Plasmodium falciparum mutations in resistance to amodiaquine and sulfadoxine-pyrimethamine in Burkina Faso.
Dokomajilar C, Lankoande Z, Dorsey G, Zongo I, Ouedraogo J, Rosenthal P. Roles of specific Plasmodium falciparum mutations in resistance to amodiaquine and sulfadoxine-pyrimethamine in Burkina Faso. American Journal Of Tropical Medicine And Hygiene 2006, 75: 162-5. PMID: 16837725, DOI: 10.4269/ajtmh.2006.75.162.Peer-Reviewed Original ResearchMeSH KeywordsAmodiaquineAnimalsAntimalarialsBurkina FasoDihydropteroate SynthaseDrug CombinationsDrug ResistanceGenes, MDRHumansMembrane ProteinsMembrane Transport ProteinsMutationPlasmodium falciparumPolymorphism, GeneticProtozoan ProteinsPyrimethamineRecurrenceSulfadoxineTetrahydrofolate DehydrogenaseConceptsUncomplicated Plasmodium falciparum malariaPlasmodium falciparum mutationsPlasmodium falciparum malariaP. falciparum resistanceFalciparum malariaFalciparum resistanceNew infectionsAmodiaquineDhfr-164LBobo-DioulassoSignificant increaseBurkina FasoSame mutationTreatmentKey polymorphismsMutationsTarget genesTherapyInfectionMalariaPrevalenceRecrudescence
2005
Usefulness of the Plasmodium falciparum chloroquine resistance transporter T76 genotype failure index for the estimation of in vivo chloroquine resistance in Burkina Faso.
Tinto H, Sanou B, Dujardin J, Ouédraogo J, VAN Overmeir C, Erhart A, VAN Marck E, Guiguemdé T, D'Alessandro U. Usefulness of the Plasmodium falciparum chloroquine resistance transporter T76 genotype failure index for the estimation of in vivo chloroquine resistance in Burkina Faso. American Journal Of Tropical Medicine And Hygiene 2005, 73: 171-3. PMID: 16014853, DOI: 10.4269/ajtmh.2005.73.171.Peer-Reviewed Original Research
2002
Chloroquine and sulphadoxine‐pyrimethamine efficacy for uncomplicated malaria treatment and haematological recovery in children in Bobo‐Dioulasso, Burkina Faso during a 3‐year period 1998–2000
Tinto H, Zoungrana E, Coulibaly S, Ouedraogo J, Traoré M, Guiguemde T, Van Marck E, D'Alessandro U. Chloroquine and sulphadoxine‐pyrimethamine efficacy for uncomplicated malaria treatment and haematological recovery in children in Bobo‐Dioulasso, Burkina Faso during a 3‐year period 1998–2000. Tropical Medicine And International Health 2002, 7: 925-930. PMID: 12390597, DOI: 10.1046/j.1365-3156.2002.00952.x.Peer-Reviewed Original ResearchConceptsPrevalence of anemiaClinical failureParasitological resistancePacked cell volumeUncomplicated malariaDay 14Day 0Uncomplicated malaria treatmentHaematological recoveryMalaria treatmentCQ resistanceHealth centersRegular surveillanceAntimalarial drugsChloroquineBurkina FasoPrevalenceBobo-DioulassoChildrenAnemiaEvidence of increasesMalariaTreatmentFailureCell volume
1994
Ten-year surveillance of drug-resistant malaria in Burkina Faso (1982-1991).
Guiguemde T, Aouba A, Ouedraogo J, Lamizana L. Ten-year surveillance of drug-resistant malaria in Burkina Faso (1982-1991). American Journal Of Tropical Medicine And Hygiene 1994, 50: 699-704. PMID: 8024062, DOI: 10.4269/ajtmh.1994.50.699.Peer-Reviewed Original ResearchConceptsTen-year surveillanceBobo-DioulassoDrug-resistant malariaDrug-resistant formsPrevalence of resistanceFirst caseChloroquine sensitivityVivo resistanceCases of resistanceMalaria transmissionBurkina FasoPlasmodium falciparumMefloquineHigh rateMalariaPyrimethamineChloroquineVitroVivoActive surveyLevel of resistancePrevalence
1992
Variation of the parasite density of Plasmodium falciparum in asymptomatic carriers: consequences for malaria chemoresistance studies.
Guiguemde T, Toe A, Sadeler B, Gbary A, Ouedraogo J, Louboutin-Croc J. Variation of the parasite density of Plasmodium falciparum in asymptomatic carriers: consequences for malaria chemoresistance studies. Medecine Tropicale 1992, 52: 313-5. PMID: 1435194.Peer-Reviewed Original ResearchConceptsDay 4Parasite densityDay 0Plasmodium falciparumAsymptomatic peopleAsymptomatic carriersInclusion criteriaMalaria prevalenceStudy 16Drug absorptionPrimary school childrenParasitaemiaBobo-DioulassoNycthemeral variationsFurther studiesSignificant differencesChildrenSchool childrenVivo testsFalciparumNegativationChemosensitivityGreater numberPrevalenceChemoresistance