2024
Comparison of test performance of a conventional PCR and two field-friendly tests to detect Coxiella burnetii DNA in ticks using Bayesian latent class analysis
Kamau M, Witte C, Goosen W, Mutinda M, Villinger J, Getange D, Khogali R, von Fricken M, Fèvre E, Zimmerman D, Linton Y, Miller M. Comparison of test performance of a conventional PCR and two field-friendly tests to detect Coxiella burnetii DNA in ticks using Bayesian latent class analysis. Frontiers In Veterinary Science 2024, 11: 1396714. PMID: 38962707, PMCID: PMC11220323, DOI: 10.3389/fvets.2024.1396714.Peer-Reviewed Original ResearchBayesian latent class analysisC. burnetii DNAEpidemiological roleHuman Q fever outbreakBayesian latent class analysis modelWild animalsDetect Coxiella burnetii DNADetect C. burnetii DNACoxiella burnetii DNAWild animal samplesPCR-HRMQ fever outbreakField-friendly techniquePositive ticksPCR high-resolution meltingTicksPCR-HRM assayZoonotic threatAnimal samplesWild animal habitatsQ feverHigh-resolution meltingMolecular techniquesCPCREstimate SECoxiella burnetii serostatus in dromedary camels (Camelus dromedarius) is associated with the presence of C. burnetii DNA in attached ticks in Laikipia County, Kenya
Rooney T, Fèvre E, Villinger J, Brenn‐White M, Cummings C, Chai D, Kamau J, Kiyong'a A, Getange D, Ochieng D, Kivali V, Zimmerman D, Rosenbaum M, Nutter F, Deem S. Coxiella burnetii serostatus in dromedary camels (Camelus dromedarius) is associated with the presence of C. burnetii DNA in attached ticks in Laikipia County, Kenya. Zoonoses And Public Health 2024, 71: 503-514. PMID: 38627945, DOI: 10.1111/zph.13127.Peer-Reviewed Original ResearchPCR-positive ticksCoxiella-like endosymbiontsTick poolsPresence of C. burnetii DNADromedary camelsCamelus dromedariusPrevalence of C. burnetiiEpidemiology of Q feverZoonotic diseaseIncreased total solidsQ feverAntibody test kitBacterium Coxiella burnetiiLivestock speciesTotal solidsTicksC. burnetiiReproductive lossesSubclinical infectionCamelsCoxiella burnetiiAge classesLivestockPublic health importanceDromedariusData release: targeted systematic literature search for tick and tick-borne pathogen distributions in six countries in sub-Saharan Africa from 1901 to 2020
Lilak A, Pecor D, Matulis G, Potter A, Wofford R, Kearney M, Mitchell S, Jaradat F, Kano A, Zimmerman D, Hassell J, Kumsa B, Kamau M, Linton Y, von Fricken M. Data release: targeted systematic literature search for tick and tick-borne pathogen distributions in six countries in sub-Saharan Africa from 1901 to 2020. Parasites & Vectors 2024, 17: 84. PMID: 38389097, PMCID: PMC10885379, DOI: 10.1186/s13071-023-06086-4.Peer-Reviewed Original Research
2023
Correction: Detection of novel coronaviruses in bats in Myanmar
Valitutto M, Aung O, Naing Tun K, Vodzak M, Zimmerman D, Yu J, Win Y, Maw M, Thein W, Win H, Dhanota J, Ontiveros V, Smith B, Tremeau-Bravard A, Goldstein T, Johnson C, Murray S, Mazet J. Correction: Detection of novel coronaviruses in bats in Myanmar. PLOS ONE 2023, 18: e0295490. PMID: 38048309, PMCID: PMC10695361, DOI: 10.1371/journal.pone.0295490.Peer-Reviewed Original ResearchAIR SAC TREMATODES (CYCLOCOELIDAE STOSSICH, 1902) INFECTING BIRDS IN ZOOLOGICAL INSTITUTIONS IN THE UNITED STATES
Greiner E, Zimmerman D, Delaski K, Dronen N, Hammond E, Stacy B, Grillo J, MacLean R, Maurer J, Okimoto B, Douglass M, Yu J, Reavill D. AIR SAC TREMATODES (CYCLOCOELIDAE STOSSICH, 1902) INFECTING BIRDS IN ZOOLOGICAL INSTITUTIONS IN THE UNITED STATES. Journal Of Zoo And Wildlife Medicine 2023, 54: 379-386. PMID: 37428703, DOI: 10.1638/2021-0159.Peer-Reviewed Original ResearchConceptsInfected host speciesWild-caught birdsNonnative snailsHost speciesPasseriform birdsCaptive individualsLarval trematode infectionsIndoor aviaryAdult speciesAvian speciesSpeciesBirdsSnail intermediate hostIntermediate hostsAviariesZoological institutionsTrematode infectionsLarvaeSpSnailsTrematodesHostPCRAdult flukesFlukesProjecting the impact of an ebola virus outbreak on endangered mountain gorillas
Zimmerman D, Hardgrove E, Sullivan S, Mitchell S, Kambale E, Nziza J, Ssebide B, Shalukoma C, Cranfield M, Pandit P, Troth S, Callicrate T, Miller P, Gilardi K, Lacy R. Projecting the impact of an ebola virus outbreak on endangered mountain gorillas. Scientific Reports 2023, 13: 5675. PMID: 37029156, PMCID: PMC10082040, DOI: 10.1038/s41598-023-32432-8.Peer-Reviewed Original ResearchComparing Predictors and Outcomes of Higher Allostatic Load across Zoo-Housed African Great Apes
Edes A, Edwards K, Zimmerman D, Jourdan B, Crews D, Wolfe B, Neiffer D, Brown J. Comparing Predictors and Outcomes of Higher Allostatic Load across Zoo-Housed African Great Apes. Journal Of Zoological And Botanical Gardens 2023, 4: 158-175. DOI: 10.3390/jzbg4010016.Peer-Reviewed Original ResearchAuthor Correction: Predicting the potential for zoonotic transmission and host associations for novel viruses
Pandit P, Anthony S, Goldstein T, Olival K, Doyle M, Gardner N, Bird B, Smith W, Wolking D, Gilardi K, Monagin C, Kelly T, Uhart M, Epstein J, Machalaba C, Rostal M, Dawson P, Hagan E, Sullivan A, Li H, Chmura A, Latinne A, Lange C, O’Rourke T, Olson S, Keatts L, Mendoza A, Perez A, de Paula C, Zimmerman D, Valitutto M, LeBreton M, McIver D, Islam A, Duong V, Mouiche M, Shi Z, Mulembakani P, Kumakamba C, Ali M, Kebede N, Tamoufe U, Bel-Nono S, Camara A, Pamungkas J, Coulibaly K, Abu-Basha E, Kamau J, Silithammavong S, Desmond J, Hughes T, Shiilegdamba E, Aung O, Karmacharya D, Nziza J, Ndiaye D, Gbakima A, sajali Z, Wacharapluesadee S, Robles E, Ssebide B, Suzán G, Aguirre L, Solorio M, Dhole T, Nga N, Hitchens P, Joly D, Saylors K, Fine A, Murray S, Karesh W, Daszak P, Mazet J, Johnson C. Author Correction: Predicting the potential for zoonotic transmission and host associations for novel viruses. Communications Biology 2023, 6: 25. PMID: 36627372, PMCID: PMC9832161, DOI: 10.1038/s42003-022-04364-y.Peer-Reviewed Original Research
2022
A Novel Coronavirus and a Broad Range of Viruses in Kenyan Cave Bats
Kamau J, Ergunay K, Webala P, Justi S, Bourke B, Kamau M, Hassell J, Chege M, Mwaura D, Simiyu C, Kibiwot S, Onyuok S, Caicedo-Quiroga L, Li T, Zimmerman D, Linton Y. A Novel Coronavirus and a Broad Range of Viruses in Kenyan Cave Bats. Viruses 2022, 14: 2820. PMID: 36560824, PMCID: PMC9785147, DOI: 10.3390/v14122820.Peer-Reviewed Original ResearchValue Ranges and Clinical Comparisons of Serum DHEA-S, IL-6, and TNF-α in Western Lowland Gorillas
Edes AN, Zimmerman D, Jourdan B, Brown JL, Edwards KL. Value Ranges and Clinical Comparisons of Serum DHEA-S, IL-6, and TNF-α in Western Lowland Gorillas. Animals 2022, 12: 2705. PMID: 36230446, PMCID: PMC9559573, DOI: 10.3390/ani12192705.Peer-Reviewed Original ResearchInterleukin-6Assessment of healthSerum DHEAClinical symptomsTumor necrosisAdditional biomarkersClinical comparisonImmune responseHealth statusClinical variationDHEATNFBiomarkersSpecies-typical levelsReference intervalsClinical samplesAvailable kitsWestern lowland gorillasSignificant differencesNon-clinical sampleAgeLowland gorillasHealthLack of informationHuman carePredicting the potential for zoonotic transmission and host associations for novel viruses
Pandit P, Anthony S, Goldstein T, Olival K, Doyle M, Gardner N, Bird B, Smith W, Wolking D, Gilardi K, Monagin C, Kelly T, Uhart M, Epstein J, Machalaba C, Rostal M, Dawson P, Hagan E, Sullivan A, Li H, Chmura A, Latinne A, Lange C, O’Rourke T, Olson S, Keatts L, Mendoza A, Perez A, de Paula C, Zimmerman D, Valitutto M, LeBreton M, McIver D, Islam A, Duong V, Mouiche M, Shi Z, Mulembakani P, Kumakamba C, Ali M, Kebede N, Tamoufe U, Bel-Nono S, Camara A, Pamungkas J, Coulibaly K, Abu-Basha E, Kamau J, Silithammavong S, Desmond J, Hughes T, Shiilegdamba E, Aung O, Karmacharya D, Nziza J, Ndiaye D, Gbakima A, Sajali Z, Wacharapluesadee S, Robles E, Ssebide B, Suzán G, Aguirre L, Solorio M, Dhole T, Nga N, Hitchens P, Joly D, Saylors K, Fine A, Murray S, Karesh W, Daszak P, Mazet J, Johnson C. Predicting the potential for zoonotic transmission and host associations for novel viruses. Communications Biology 2022, 5: 844. PMID: 35986178, PMCID: PMC9390964, DOI: 10.1038/s42003-022-03797-9.Peer-Reviewed Original ResearchConceptsVirus-host associationsHost-virus associationsEvolutionary selection pressureCross-species transmissionNovel virusHost associationsHost speciesSelection pressureHost rangeVirus-host networksWildlife surveillancePrioritization scoresAnimal-human interfaceZoonotic transmissionVirusHuman infectionsKnowledge gapsSpeciesRelevant contextPathwayHumansHostGreater numberPotential human infectionFamilyMetagenomic Investigation of Ticks From Kenyan Wildlife Reveals Diverse Microbial Pathogens and New Country Pathogen Records
Ergunay K, Mutinda M, Bourke B, Justi SA, Caicedo-Quiroga L, Kamau J, Mutura S, Akunda IK, Cook E, Gakuya F, Omondi P, Murray S, Zimmerman D, Linton YM. Metagenomic Investigation of Ticks From Kenyan Wildlife Reveals Diverse Microbial Pathogens and New Country Pathogen Records. Frontiers In Microbiology 2022, 13: 932224. PMID: 35847110, PMCID: PMC9283121, DOI: 10.3389/fmicb.2022.932224.Peer-Reviewed Original ResearchDiverse microbial pathogensPathogenic bacterial speciesHuman mastadenovirus CVertebrate taxaPhylogenetic reconstructionMajor phylaFungal speciesMetagenomic investigationWild ungulatesMicrobial pathogensBacterial speciesWild animalsRelative abundanceSignificant divergenceHuman pathogenicitySpeciesPathogen transferPathogensBovine herpesvirus 5Filarial pathogensVirus 1First reportKenyan drylandsPoolTicksFemale Health Across the Tree of Life: Insights at the Intersection of Women's Health, One Health and Planetary Health
Natterson-Horowitz B, Boddy AM, Zimmerman D. Female Health Across the Tree of Life: Insights at the Intersection of Women's Health, One Health and Planetary Health. PNAS Nexus 2022, 1: pgac044. PMID: 35668878, PMCID: PMC9154074, DOI: 10.1093/pnasnexus/pgac044.Peer-Reviewed Original ResearchTree of lifeImportance of biodiversityAnimal populationsLevel of resistanceHealth prevention effortsWomen's healthFemale animalsAnimal's environmentBiological characteristicsFemale healthSpeciesEnvironmental factorsTreesComparative approachRich sourceSimilar environmental hazardsHuman healthEndometrial cancerAnimalsBiodiversityNoncommunicable diseasesInterdependence of humansPhysiologic adaptationsInsightsPrevention effortsGreat ape health watch: Enhancing surveillance for emerging infectious diseases in great apes
Zimmerman DM, Mitchell SL, Wolf TM, Deere JR, Noheri JB, Takahashi E, Cranfield MR, Travis DA, Hassell JM. Great ape health watch: Enhancing surveillance for emerging infectious diseases in great apes. American Journal Of Primatology 2022, 84: e23379. PMID: 35389523, DOI: 10.1002/ajp.23379.Peer-Reviewed Original ResearchStrengthening global health security by improving disease surveillance in remote rural areas of low-income and middle-income countries
Worsley-Tonks KEL, Bender JB, Deem SL, Ferguson AW, Fèvre EM, Martins DJ, Muloi DM, Murray S, Mutinda M, Ogada D, Omondi GP, Prasad S, Wild H, Zimmerman DM, Hassell JM. Strengthening global health security by improving disease surveillance in remote rural areas of low-income and middle-income countries. The Lancet Global Health 2022, 10: e579-e584. PMID: 35303467, PMCID: PMC8923676, DOI: 10.1016/s2214-109x(22)00031-6.Peer-Reviewed Original ResearchConceptsMiddle-income countriesDisease surveillanceGlobal health securityNational surveillance systemRural areasHealth securityRemote rural areasRoutine exposureHealth careZoonotic diseaseCOVID-19 pandemicSurveillanceZoonotic disease surveillanceSurveillance effortsFrequent contactSurveillance systemRural communitiesCharacterizing Husbandry Risk Factors Associated with Metastatic Soft Tissue Mineralization in Zoo-Housed Komodo Dragons (Varanus komodoensis) in the United States
Zimmerman D, Yu J, Schaftenaar W, Debnar L, Reavill D, Garner M, Mitchell M. Characterizing Husbandry Risk Factors Associated with Metastatic Soft Tissue Mineralization in Zoo-Housed Komodo Dragons (Varanus komodoensis) in the United States. Journal Of Herpetological Medicine And Surgery 2022, 32: 73-83. DOI: 10.5818/jhms-d-21-00022.1.Peer-Reviewed Original ResearchAbsence of molecular evidence of filovirus circulating in bats and rodents in Laikipia North Sub-county, Kenya: a cross sectional study
Ambala P, Hussein F, Mutura S, Gachara G, Menza N, Shields L, Vodzak M, Murray S, Valitutto M, Zimmerman D, Kamau J. Absence of molecular evidence of filovirus circulating in bats and rodents in Laikipia North Sub-county, Kenya: a cross sectional study. PAMJ - One Health 2022, 7 DOI: 10.11604/pamj-oh.2022.7.34.33231.Peer-Reviewed Original Research
2021
RETROSPECTIVE STUDY OF MORBIDITY AND MORTALITY OF AFRICAN PENGUINS (SPHENISCUS DEMERSUS) UNDER MANAGED CARE IN NORTH AMERICA: 20072018
Trumpp K, Sander S, Sander W, Zimmerman D, Bronson E. RETROSPECTIVE STUDY OF MORBIDITY AND MORTALITY OF AFRICAN PENGUINS (SPHENISCUS DEMERSUS) UNDER MANAGED CARE IN NORTH AMERICA: 20072018. Journal Of Zoo And Wildlife Medicine 2021, 52: 1135-1142. PMID: 34998282, DOI: 10.1638/2020-0224.Peer-Reviewed Original ResearchConceptsCause of deathYr of ageCommon morbidityRetrospective studySystemic diseaseTreatment regimensAspergillosis casesCare teamCommon causeMalaria casesNeurologic diseaseRespiratory diseaseMultifactorial conditionMorbidityHealthcare resourcesMortality trendsMortalityDiseaseManaged CarePreventative medicineCareCauseDeathAnimal care teamEnhanced levelsMolecular evidence of Anaplasma phagocytophilum in olive baboons and vervet monkeys in Kenya
Masika SJ, Muchemi GM, Okumu TA, Mutura S, Zimmerman D, Kamau J. Molecular evidence of Anaplasma phagocytophilum in olive baboons and vervet monkeys in Kenya. BMC Veterinary Research 2021, 17: 385. PMID: 34906141, PMCID: PMC8669034, DOI: 10.1186/s12917-021-03095-2.Peer-Reviewed Original ResearchConceptsPolymerase chain reactionAnaplasma phagocytophilumConventional polymerase chain reactionA. phagocytophilumTick-borne infectionsVervet monkeysPublic health implicationsZoonotic A. phagocytophilumOlive baboonsOverall prevalenceBlood samplesConclusionThis studyTropical diseasesGranulocytic anaplasmosisAnaplasma speciesChain reactionHealth implicationsIntracellular bacteriaBaboonsPhagocytophilumMonkeysPrevalenceObligate intracellular bacteriaIxodid ticksInfectionCharacterizing Husbandry Risk Factors Associated with Metastatic Soft Tissue Mineralization in Zoo-Housed Komodo Dragons (Varanus komodoensis) in the United States
Zimmerman D, Yu J, Schaftenaar W, Debnar L, Reavill D, Garner M, Mitchell M. Characterizing Husbandry Risk Factors Associated with Metastatic Soft Tissue Mineralization in Zoo-Housed Komodo Dragons (Varanus komodoensis) in the United States. Journal Of Herpetological Medicine And Surgery 2021 DOI: 10.5818/jhms-d-21-00022.Peer-Reviewed Original Research