2013
Interaction of Fatty Acid Genotype and Diet on Changes in Colonic Fatty Acids in a Mediterranean Diet Intervention Study
Porenta S, Ko Y, Raskin L, Gruber S, Mukherjee B, Baylin A, Ren J, Djuric Z. Interaction of Fatty Acid Genotype and Diet on Changes in Colonic Fatty Acids in a Mediterranean Diet Intervention Study. Cancer Prevention Research 2013, 6: 1212-1221. PMID: 24022589, PMCID: PMC3840911, DOI: 10.1158/1940-6207.capr-13-0131.Peer-Reviewed Original ResearchConceptsFatty acid desaturaseHealthy Eating dietArachidonic acid concentrationIntake of n-3Fatty acid desaturase genotypeIncreased risk of colon cancerN-6 fatty acidsEating dietsIntake of n-6 fatty acidsRisk of colon cancerFatty acid desaturase gene clusterDietary fat intakeColon cancer riskSerum eicosapentaenoic acidDiet intervention studyInteraction of polymorphismsSerum arachidonic acidFatty acid desaturase geneFatty acidsSingle-nucleotide polymorphismsFat intakeN-3N-6Colon cancerAssociated with genotype
2010
HFE H63D Polymorphism as a Modifier of the Effect of Cumulative Lead Exposure on Pulse Pressure: The Normative Aging Study
Zhang A, Park S, Wright R, Weisskopf M, Mukherjee B, Nie H, Sparrow D, Hu H. HFE H63D Polymorphism as a Modifier of the Effect of Cumulative Lead Exposure on Pulse Pressure: The Normative Aging Study. Environmental Health Perspectives 2010, 118: 1261-1266. PMID: 20478760, PMCID: PMC2944087, DOI: 10.1289/ehp.1002251.Peer-Reviewed Original ResearchConceptsCumulative lead exposureHFE H63D polymorphismC282Y variantBone lead levelsAssociated with steeper increasesLinear mixed-effects regression modelsFamily history of hypertensionMixed-effects regression modelsDaily intake of calciumNormative Aging StudyPredictor of cardiovascular diseaseWaist circumferenceIntake of calciumHistory of hypertensionLead exposureH63D polymorphismAlcohol intakeRandom interceptFamily historyMarker of arterial stiffnessTotal caloriesAging StudySteeper increasesLead levelsCardiovascular disease