2017
Construction of environmental risk score beyond standard linear models using machine learning methods: application to metal mixtures, oxidative stress and cardiovascular disease in NHANES
Park S, Zhao Z, Mukherjee B. Construction of environmental risk score beyond standard linear models using machine learning methods: application to metal mixtures, oxidative stress and cardiovascular disease in NHANES. Environmental Health 2017, 16: 102. PMID: 28950902, PMCID: PMC5615812, DOI: 10.1186/s12940-017-0310-9.Peer-Reviewed Original ResearchConceptsEnvironmental risk scoreBayesian kernel machine regressionNational Health and Nutrition Examination SurveyHealth and Nutrition Examination SurveyRisk scoreAssociated with odds ratiosNutrition Examination SurveyAssociated with systolicExamination SurveyMulti-pollutant approachKernel machine regressionPollutant mixturesSD increaseEpidemiological researchDiastolic blood pressureMortality outcomesOdds ratioBayesian additive regression treesDisease endpointsHealth endpointsCumulative riskPositive associationEnvironmental exposuresIntermediate markersCardiovascular disease
2015
Extreme Air Pollution Conditions Adversely Affect Blood Pressure and Insulin Resistance
Brook R, Sun Z, Brook J, Zhao X, Ruan Y, Yan J, Mukherjee B, Rao X, Duan F, Sun L, Liang R, Lian H, Zhang S, Fang Q, Gu D, Sun Q, Fan Z, Rajagopalan S. Extreme Air Pollution Conditions Adversely Affect Blood Pressure and Insulin Resistance. Hypertension 2015, 67: 77-85. PMID: 26573709, PMCID: PMC4830086, DOI: 10.1161/hypertensionaha.115.06237.Peer-Reviewed Original ResearchConceptsFine particulate matterParticulate matterAmbient fine particulate matterSD increaseAssociated with worsening insulin resistanceBlack carbon levelsBlack carbon exposurePublic health warningsAir pollutionBeijing metropolitan areaBlack carbonHealth warningsAssociated with rangeCardiometabolic healthCarbon levelsDiastolic blood pressureExposure windowsCardiometabolic diseasesHealth effectsNonsmoking adultsMetabolic syndromeDeveloping world todayCarbon exposureSystolic blood pressure elevationHealth