Per- and Polyfluoroalkyl Substances and Hormone Levels During the Menopausal Transition
Harlow S, Hood M, Ding N, Mukherjee B, Calafat A, Randolph J, Gold E, Park S. Per- and Polyfluoroalkyl Substances and Hormone Levels During the Menopausal Transition. The Journal Of Clinical Endocrinology & Metabolism 2021, 106: e4427-e4437. PMID: 34181018, PMCID: PMC8677593, DOI: 10.1210/clinem/dgab476.Peer-Reviewed Original ResearchConceptsMidlife womenSex hormone-binding globulinFollicle-stimulating hormoneInverse associationStudy of Women's HealthPositive associationMenopausal transitionBody mass indexReproductive ageWomen's HealthSignificant linear trendNo significant associationNulliparous womenLinear mixed modelsSmoking statusYears of ageMass indexHormone-binding globulinMenopausal statusLongitudinal serum concentrationsSignificant associationSerum PFAS concentrationsMidlifeWomenPolyfluoroalkyl substances