2022
Predicting cumulative lead (Pb) exposure using the Super Learner algorithm
Wang X, Bakulski K, Mukherjee B, Hu H, Park S. Predicting cumulative lead (Pb) exposure using the Super Learner algorithm. Chemosphere 2022, 311: 137125. PMID: 36347347, PMCID: PMC10160242, DOI: 10.1016/j.chemosphere.2022.137125.Peer-Reviewed Original ResearchConceptsPatella leadNational Health and Nutrition Examination SurveyHealth and Nutrition Examination SurveyNutrition Examination SurveyLong-term health effectsPopulation-based studyK-shell X-ray fluorescenceNormative Aging StudyCumulative lead exposureEvaluate health effectsExamination SurveyLead concentrationsBone lead measurementsAging StudyTibia leadPositive associationStudy populationHealth effectsRegression-based predictive modelBone lead concentrationsBlood pressureFlexible machine learning approachCorrelation coefficientX-ray fluorescence techniqueLead measurements
2018
Bone Lead Levels and Risk of Incident Primary Open-Angle Glaucoma: The VA Normative Aging Study
Wang W, Moroi S, Bakulski K, Mukherjee B, Weisskopf M, Schaumberg D, Sparrow D, Vokonas P, Hu H, Park S. Bone Lead Levels and Risk of Incident Primary Open-Angle Glaucoma: The VA Normative Aging Study. Environmental Health Perspectives 2018, 126: 087002. PMID: 30102601, PMCID: PMC6108844, DOI: 10.1289/ehp3442.Peer-Reviewed Original ResearchConceptsPrimary open-angle glaucomaIncident primary open-angle glaucomaRisk of primary open-angle glaucomaOpen-angle glaucomaHazard ratioIncident cases of POAGCases of primary open-angle glaucomaAsymmetric cup-to-disc ratioFollow-upPrimary open-angle glaucoma casesEtiology of primary open-angle glaucomaCup-to-disc ratioVisual field defectsCox proportional hazards regressionAssociated with hazard ratiosProportional hazards regressionOxidative stressEstimate hazard ratiosDisc hemorrhageOcular evaluationPatella leadField defectsCumulative lead doseProspective cohortSurvival curves
2009
Bone Lead Level Prediction Models and Their Application to Examine the Relationship of Lead Exposure and Hypertension in the Third National Health and Nutrition Examination Survey
Park S, Mukherjee B, Xia X, Sparrow D, Weisskopf M, Nie H, Hu H. Bone Lead Level Prediction Models and Their Application to Examine the Relationship of Lead Exposure and Hypertension in the Third National Health and Nutrition Examination Survey. Journal Of Occupational And Environmental Medicine 2009, 51: 1422-1436. PMID: 19952788, PMCID: PMC2939477, DOI: 10.1097/jom.0b013e3181bf6c8d.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedAged, 80 and overBone and BonesBostonCohort StudiesEnvironmental ExposureFemaleHumansHypertensionLeadLongitudinal StudiesMaleMiddle AgedNutrition SurveysPatellaRadiographyRegression AnalysisRisk AssessmentRisk FactorsSpectrometry, X-Ray EmissionTibiaUnited StatesUnited States Department of Veterans AffairsYoung AdultConceptsNational Health and Nutrition Examination SurveyThird National Health and Nutrition Examination SurveyHealth and Nutrition Examination SurveyNutrition Examination SurveyCommunity-based cohortPatella leadExamination SurveyCohort of older menCommunity-based cohort of older menK X-ray fluorescenceNHANES-IIISignificant associationBlood lead levelsOlder menStandard covariatesPatellaExternal validationCorrelation coefficientBlood leadLead exposureTibiaLead levelsAssociationSurveyLead studies